microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1264 Gene

Data sources for MIR1264 Gene:

RNA type for MIR1264 Gene

miRNA

Aliases for MIR1264 Gene

External Ids for MIR1264 Gene

Previous HGNC Symbols for MIR1264 Gene

  • MIRN1264

Previous GeneCards Identifiers for MIR1264 Gene

  • GC00U923154
  • GC0XP113793
  • GC0XP113887

Summaries for MIR1264 Gene

Entrez Gene Summary for MIR1264 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1264 Gene

MIR1264 (MicroRNA 1264) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1264 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1264 Gene

Genomics for MIR1264 Gene

Genomic Locations for MIR1264 Gene

Latest Assembly
chrX:114,652,654-114,652,723
(GRCh38/hg38)
Size:
70 bases
Orientation:
Plus strand

Previous Assembly
chrX:113,887,130-113,887,198
(GRCh37/hg19 by Entrez Gene)
Size:
69 bases
Orientation:
Plus strand

Genomic View for MIR1264 Gene

Genes around MIR1264 on UCSC Golden Path with GeneCards custom track
MIR1264 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR1264 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1264 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1264 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR1264 Gene

Proteins for MIR1264 Gene

Post-translational modifications for MIR1264 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1264 Gene

Domains & Families for MIR1264 Gene

Gene Families for MIR1264 Gene

genes like me logo Genes that share domains with MIR1264: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1264 Gene

Function for MIR1264 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1264 Gene

Localization for MIR1264 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1264 Gene

Pathways & Interactions for MIR1264 Gene

PathCards logo

SuperPathways for MIR1264 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR1264 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR1264 Gene

Drugs & Compounds for MIR1264 Gene

No Compound Related Data Available

Transcripts for MIR1264 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR1264 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075A661_9606 precursor_RNA 69 3

RefSeq: NR_031563,

Ensembl: ENST00000616374 (view in UCSC) ,

miRBase: MI0003758,

URS0000759E8E_9606 miRNA 23 2

RefSeq: NR_031563,

miRBase: MIMAT0005791,

URS0000EFC3E7_9606 precursor_RNA 64 1

MirGeneDB: Hsa-Mir-95-P4,

URS00003205EB_9606 miRNA 22 1

MirGeneDB: Hsa-Mir-95-P4_5p,

URS0000D4F1F2_9606 miRNA 22 1

MirGeneDB: Hsa-Mir-95-P4_3p,

MIR1264 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1264 Gene

No ASD Table

Relevant External Links for MIR1264 Gene

GeneLoc Exon Structure for
MIR1264

No data available for mRNA/cDNA for MIR1264 Gene

Expression for MIR1264 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR1264

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1264 Gene

Orthologs for MIR1264 Gene

Evolution for MIR1264 Gene

ENSEMBL:
Gene Tree for MIR1264 (if available)
TreeFam:
Gene Tree for MIR1264 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR1264

No data available for Orthologs for MIR1264 Gene

Paralogs for MIR1264 Gene

No data available for Paralogs for MIR1264 Gene

Variants for MIR1264 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR1264 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR1264 Gene

Variant ID Type Subtype PubMed ID
esv33994 CNV gain+loss 17666407
nsv527347 CNV gain 19592680
nsv7044 CNV deletion 18451855

Additional Variant Information for MIR1264 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1264
Leiden Open Variation Database (LOVD)
MIR1264

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR1264 Gene

Disorders for MIR1264 Gene

Additional Disease Information for MIR1264

No disorders were found for MIR1264 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1264 Gene

Publications for MIR1264 Gene

  1. Down-regulation of hsa-miR-1264 contributes to DNMT1-mediated silencing of SOCS3. (PMID: 26047583) Boosani CS … Agrawal DK (Molecular biology reports 2015) 2 3
  2. LncRNA SOCS2-AS1 inhibits progression and metastasis of colorectal cancer through stabilizing SOCS2 and sponging miR-1264. (PMID: 32437330) Zheng Z … Ruan X (Aging 2020) 3
  3. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3
  5. Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. (PMID: 16954537) Berezikov E … Cuppen E (Genome research 2006) 3

Products for MIR1264 Gene

Sources for MIR1264 Gene