microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1262 Gene

Subcategory (RNA class) for MIR1262 Gene

miRNA

Number of RNA Genes sources:

3 / 17

Aliases for MIR1262 Gene

  • MicroRNA 1262 2 3 5
  • Hsa-Mir-1262 2 3
  • MIR1262 2 5
  • MIMAT0005914 50
  • Hsa-MiR-1262 173
  • MI0006397 50
  • MIRN1262 3
  • Mir-1262 3

External Ids for MIR1262 Gene

Previous HGNC Symbols for MIR1262 Gene

  • MIRN1262

Previous GeneCards Identifiers for MIR1262 Gene

  • GC00U922930
  • GC01M068422
  • GC01M068649

Summaries for MIR1262 Gene

Entrez Gene Summary for MIR1262 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1262 Gene

MIR1262 (MicroRNA 1262) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1262 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1262 Gene

Genomics for MIR1262 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR1262 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J068217 Enhancer 1.2 ENCODE CraniofacialAtlas dbSUPER 11.5 -34.7 -34736 2.1 TEAD4 PRDM10 ZNF629 ZNF692 ZIC2 ZSCAN4 PATZ1 ZNF501 ZNF600 ZNF341 MIR1262 WLS DIRAS3
GH01J068218 Enhancer 1.1 ENCODE dbSUPER 11.5 -33.6 -33635 0.1 PRDM10 ZNF629 ZNF692 ZIC2 ZSCAN4 PATZ1 ZNF501 ZNF341 ZNF561 ZNF792 MIR1262 WLS DIRAS3
GH01J068204 Enhancer 1.1 Ensembl ENCODE dbSUPER 11.3 -24.5 -24491 9 ATF7 RFX1 PRDM1 SP1 ZNF600 SCRT2 ZBTB44 BMI1 EZH2 ZSCAN5C MIR1262 WLS DIRAS3
GH01J068291 Enhancer 1.1 ENCODE CraniofacialAtlas 10.8 -109.7 -109669 3.5 TEAD4 ZNF629 ZNF692 JUND PRDM1 ZIC2 ZSCAN4 PKNOX1 POLR2A ZNF24 HSALNG0004312 LOC105378782 MIR1262 RPE65 WLS lnc-GADD45A-8
GH01J068213 Enhancer 1 ENCODE dbSUPER 11.5 -30.9 -30917 1.6 ZNF221 PRDM10 ZNF629 ZIC2 ZSCAN4 SP1 ZNF600 ZNF561 SCRT2 ZBTB44 MIR1262 WLS DIRAS3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR1262 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR1262 Gene

Genomic Locations for MIR1262 Gene
chr1:68,183,518-68,183,610
(GRCh38/hg38)
Size:
93 bases
Orientation:
Minus strand
chr1:68,649,201-68,649,293
(GRCh37/hg19)
Size:
93 bases
Orientation:
Minus strand

Genomic View for MIR1262 Gene

Genes around MIR1262 on UCSC Golden Path with GeneCards custom track
MIR1262 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR1262 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1262 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1262 Gene

Proteins for MIR1262 Gene

Post-translational modifications for MIR1262 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1262 Gene

Domains & Families for MIR1262 Gene

Gene Families for MIR1262 Gene

HGNC:
genes like me logo Genes that share domains with MIR1262: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1262 Gene

Function for MIR1262 Gene

Phenotypes From GWAS Catalog for MIR1262 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1262 Gene

Localization for MIR1262 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR1262 gene
Compartment Confidence
extracellular 1
nucleus 1
lysosome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1262 Gene

Pathways & Interactions for MIR1262 Gene

PathCards logo

SuperPathways for MIR1262 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR1262 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR1262 Gene

Drugs & Compounds for MIR1262 Gene

No Compound Related Data Available

Transcripts for MIR1262 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR1262 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075B14C_9606 precursor_RNA 93 5

HGNC: 35328,

RefSeq: NR_031664,

Ensembl: ENST00000408276 (view in UCSC) ,

miRBase: MI0006397,

ENA: LM610153.1:1..93:precursor_RNA,

URS0000568FF8_9606 miRNA 22 4

RefSeq: NR_031664,

miRBase: MIMAT0005914,

TarBase: hsa-miR-1262,

ENA: LM380705.1:1..22:ncRNA, LM610153.1:14..35:ncRNA,

MIR1262 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR1262 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1262 Gene

No ASD Table

Relevant External Links for MIR1262 Gene

GeneLoc Exon Structure for
MIR1262

Expression for MIR1262 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1262 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR1262

genes like me logo Genes that share expression patterns with MIR1262: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1262 Gene

Orthologs for MIR1262 Gene

Evolution for MIR1262 Gene

ENSEMBL:
Gene Tree for MIR1262 (if available)
TreeFam:
Gene Tree for MIR1262 (if available)

No data available for Orthologs for MIR1262 Gene

Paralogs for MIR1262 Gene

No data available for Paralogs for MIR1262 Gene

Variants for MIR1262 Gene

Additional dbSNP identifiers (rs#s) for MIR1262 Gene

Additional Variant Information for MIR1262 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1262

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR1262 Gene

Disorders for MIR1262 Gene

No disorders were found for MIR1262 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1262 Gene

Publications for MIR1262 Gene

  1. A polymorphism in miR-1262 regulatory region confers the risk of lung cancer in Chinese population. (PMID: 28510306) Xie K … Hu Z (International journal of cancer 2017) 3
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  3. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR1262 Gene

Sources for MIR1262 Gene