microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1255B2 Gene

Subcategory (RNA class) for MIR1255B2 Gene

miRNA

Number of RNA Genes sources:

3 / 17

Aliases for MIR1255B2 Gene

  • MicroRNA 1255b-2 2 3 5
  • Hsa-Mir-1255b-2 2 3
  • MIR1255B2 2 5
  • Hsa-MiR-1255b-5p 173
  • MIMAT0005945 50
  • MIMAT0022725 50
  • MIR1255B-2 3
  • MIRN1255B2 3
  • MI0006436 50

External Ids for MIR1255B2 Gene

Previous HGNC Symbols for MIR1255B2 Gene

  • MIRN1255B2

Previous GeneCards Identifiers for MIR1255B2 Gene

  • GC00U922924
  • GC01P166235

Summaries for MIR1255B2 Gene

Entrez Gene Summary for MIR1255B2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1255B2 Gene

MIR1255B2 (MicroRNA 1255b-2) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1255B2 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1255B2 Gene

Genomics for MIR1255B2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR1255B2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J167997 Enhancer 0.4 Ensembl 600.7 -1.4 -1359 0.2 ZNF316 MAFK MAFF EMSY MIR1255B2 ADCY10 DCAF6 MPC2 GPR161
GH01J167999 Enhancer 0.2 Ensembl 600.7 +0.8 841 0.6 MIR1255B2 MPC2 DCAF6 ADCY10 lnc-GPR161-3 GPR161
GH01J167985 Enhancer 1.2 FANTOM5 Ensembl 0.4 -14.0 -14012 1.7 PRDM10 ZNF629 LEF1 IKZF1 ZNF692 JUND ZNF300 FOXA1 MTA2 ZNF776 POU2F1 MPZL1 ENSG00000272205 ADCY10 MPC2 RCSD1 MIR1255B2 DCAF6 GPR161
GH01J167945 Enhancer 0.6 Ensembl dbSUPER 0.2 -51.7 -51659 3.6 HMBOX1 ARNT HNF4A RXRA HNF4G ZNF121 ADCY10 MPC2 DCAF6 MIR1255B2 GPR161
GH01J167949 Enhancer 0.6 Ensembl 0.3 -48.2 -48159 2.2 PRDM1 FOXA2 ATF2 JUND ATF4 ZFP91 HNF4A FEZF1 PRDM6 KLF1 ADCY10 MPC2 DCAF6 MIR1255B2 GPR161
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR1255B2 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR1255B2 Gene

Genomic Locations for MIR1255B2 Gene
chr1:167,998,660-167,998,726
(GRCh38/hg38)
Size:
67 bases
Orientation:
Plus strand
chr1:167,967,898-167,967,964
(GRCh37/hg19)
Size:
67 bases
Orientation:
Plus strand

Genomic View for MIR1255B2 Gene

Genes around MIR1255B2 on UCSC Golden Path with GeneCards custom track
MIR1255B2 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR1255B2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1255B2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1255B2 Gene

Proteins for MIR1255B2 Gene

Post-translational modifications for MIR1255B2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1255B2 Gene

Domains & Families for MIR1255B2 Gene

Gene Families for MIR1255B2 Gene

genes like me logo Genes that share domains with MIR1255B2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1255B2 Gene

Function for MIR1255B2 Gene

Phenotypes From GWAS Catalog for MIR1255B2 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1255B2 Gene

Localization for MIR1255B2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1255B2 Gene

Pathways & Interactions for MIR1255B2 Gene

PathCards logo

SuperPathways for MIR1255B2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR1255B2 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR1255B2 Gene

Drugs & Compounds for MIR1255B2 Gene

No Compound Related Data Available

Transcripts for MIR1255B2 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR1255B2 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075CA6D_9606 precursor_RNA 67 5

HGNC: 35367,

RefSeq: NR_031702,

Ensembl: ENST00000408618 (view in UCSC) ,

miRBase: MI0006436,

ENA: LM610178.1:1..67:precursor_RNA,

URS0000211070_9606 miRNA 22 4

RefSeq: NR_031701, NR_031702,

miRBase: MIMAT0005945,

TarBase: hsa-miR-1255b-5p,

ENA: LM380722.1:1..22:ncRNA, LM610177.1:3..24:ncRNA, LM610178.1:6..27:ncRNA,

URS000075EDF2_9606 miRNA 22 3

RefSeq: NR_031702,

miRBase: MIMAT0022725,

ENA: LM610178.1:40..61:ncRNA,

MIR1255B2 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1255B2 Gene

No ASD Table

Relevant External Links for MIR1255B2 Gene

GeneLoc Exon Structure for
MIR1255B2

No data available for mRNA/cDNA for MIR1255B2 Gene

Expression for MIR1255B2 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR1255B2

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1255B2 Gene

Orthologs for MIR1255B2 Gene

Evolution for MIR1255B2 Gene

ENSEMBL:
Gene Tree for MIR1255B2 (if available)
TreeFam:
Gene Tree for MIR1255B2 (if available)

No data available for Orthologs for MIR1255B2 Gene

Paralogs for MIR1255B2 Gene

No data available for Paralogs for MIR1255B2 Gene

Variants for MIR1255B2 Gene

Additional dbSNP identifiers (rs#s) for MIR1255B2 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1255B2 Gene

Variant ID Type Subtype PubMed ID
esv32660 CNV loss 17666407
nsv1078878 OTHER inversion 25765185

Additional Variant Information for MIR1255B2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1255B2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR1255B2 Gene

Disorders for MIR1255B2 Gene

Additional Disease Information for MIR1255B2

No disorders were found for MIR1255B2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1255B2 Gene

Publications for MIR1255B2 Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR1255B2 Gene

Sources for MIR1255B2 Gene