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Aliases for MIR1254-2 Gene

Subcategory (RNA class) for MIR1254-2 Gene


Quality Score for this RNA gene is


Aliases for MIR1254-2 Gene

  • MicroRNA 1254-2 2 3 5
  • Hsa-Mir-1254-2 3

External Ids for MIR1254-2 Gene

Previous GeneCards Identifiers for MIR1254-2 Gene

  • GC10U901542
  • GC10P023683

Summaries for MIR1254-2 Gene

Entrez Gene Summary for MIR1254-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1254-2 Gene

MIR1254-2 (MicroRNA 1254-2) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1254-2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1254-2 Gene

Genomics for MIR1254-2 Gene

GeneHancer (GH) Regulatory Elements for MIR1254-2 Gene

Promoters and enhancers for MIR1254-2 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10I023412 Enhancer 1.2 FANTOM5 Ensembl ENCODE 0.4 +19.1 19128 0.9 KLF1 JUN INSM2 RFX5 ZEB1 FOSL1 ZNF366 FOS KLF8 KLF13 C10orf67 OTUD1 LOC105376453 ENSG00000227537 MIR1254-2
GH10I023408 Enhancer 0.9 ENCODE 0.4 +15.6 15557 1 PKNOX1 ARNT FEZF1 GLI4 ZNF2 ZNF213 ZNF302 FOS ATF7 SP3 OTUD1 C10orf67 LOC105376453 MIR1254-2
GH10I023413 Enhancer 1.1 FANTOM5 Ensembl ENCODE 0.3 +20.5 20501 0.8 PKNOX1 BATF IRF4 NFATC1 ATF7 PRDM10 ETV6 IKZF2 RUNX3 ZBED1 OTUD1 C10orf67 LOC105376453 MIR1254-2
GH10I023402 Enhancer 0.8 ENCODE 0.4 +10.8 10786 3.6 SOX13 TFAP4 SAP130 ZNF384 CEBPG RARA TEAD3 ZNF335 ZNF121 ZNF366 C10orf67 LOC105376453 OTUD1 ENSG00000227537 MIR1254-2
GH10I023431 Enhancer 1 FANTOM5 Ensembl ENCODE 0.3 +39.3 39325 1.8 KLF1 POLR2A STAT3 CEBPB OTUD1 C10orf67 LOC105376453 MIR1254-2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1254-2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1254-2 Gene

Genomic Locations for MIR1254-2 Gene
63 bases
Plus strand

Genomic View for MIR1254-2 Gene

Genes around MIR1254-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1254-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1254-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1254-2 Gene

Proteins for MIR1254-2 Gene

Post-translational modifications for MIR1254-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1254-2 Gene

Domains & Families for MIR1254-2 Gene

Gene Families for MIR1254-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1254-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1254-2 Gene

Function for MIR1254-2 Gene

Phenotypes From GWAS Catalog for MIR1254-2 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1254-2 Gene

Localization for MIR1254-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1254-2 Gene

Pathways & Interactions for MIR1254-2 Gene

SuperPathways for MIR1254-2 Gene

No Data Available

Interacting Proteins for MIR1254-2 Gene

Gene Ontology (GO) - Biological Process for MIR1254-2 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1254-2 Gene

Drugs & Compounds for MIR1254-2 Gene

No Compound Related Data Available

Transcripts for MIR1254-2 Gene

mRNA/cDNA for MIR1254-2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1254-2 Gene

No ASD Table

Relevant External Links for MIR1254-2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1254-2 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1254-2 Gene

Orthologs for MIR1254-2 Gene

Evolution for MIR1254-2 Gene

Gene Tree for MIR1254-2 (if available)
Gene Tree for MIR1254-2 (if available)

No data available for Orthologs for MIR1254-2 Gene

Paralogs for MIR1254-2 Gene

No data available for Paralogs for MIR1254-2 Gene

Variants for MIR1254-2 Gene

Sequence variations from dbSNP and Humsavar for MIR1254-2 Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1003313517 -- 23,393,907(+) C/T downstream_transcript_variant
rs1004583776 -- 23,393,457(+) T/C non_coding_transcript_variant
rs1006330448 -- 23,391,904(+) C/G upstream_transcript_variant
rs1007493023 -- 23,391,557(+) C/T upstream_transcript_variant
rs1007855166 -- 23,391,803(+) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1254-2 Gene

Variant ID Type Subtype PubMed ID
esv3578718 CNV loss 25503493

Additional Variant Information for MIR1254-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1254-2 Gene

Disorders for MIR1254-2 Gene

Additional Disease Information for MIR1254-2

No disorders were found for MIR1254-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1254-2 Gene

Publications for MIR1254-2 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 58

Products for MIR1254-2 Gene

Sources for MIR1254-2 Gene

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