microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1252 Gene

Data sources for MIR1252 Gene:

RNA type for MIR1252 Gene

miRNA

Aliases for MIR1252 Gene

External Ids for MIR1252 Gene

Previous HGNC Symbols for MIR1252 Gene

  • MIRN1252

Previous GeneCards Identifiers for MIR1252 Gene

  • GC00U923113
  • GC12P078338
  • GC12P079813

Summaries for MIR1252 Gene

Entrez Gene Summary for MIR1252 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1252 Gene

MIR1252 (MicroRNA 1252) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1252 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1252 Gene

Genomics for MIR1252 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR1252 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J079419 Enhancer 0.2 Ensembl 250.7 -0.7 -656 0.4 MIR1252 ENSG00000257894 HSALNG0092641 HSALNG0092639 PAWR SYT1
GH12J079565 Enhancer 1 Ensembl ENCODE 10.3 +147.4 147444 2.6 CEBPA ATF3 YY1 MXD4 FOXA1 HOMEZ FOXA2 SMAD4 RXRA SAP130 piR-39098-055 piR-32890-001 piR-47162-037 PAWR MIR1252 ENSG00000258044 piR-33422-089 lnc-PAWR-7 SYT1
GH12J079444 Enhancer 0.6 Ensembl ENCODE 11.7 +25.0 25044 1.8 MAFF MAFK MAFG NFE2L2 ZSCAN5C MIR1252 ENSG00000258044 piR-48759-062 HSALNG0092639 ENSG00000257894 PAWR SYT1
GH12J079512 Enhancer 0.6 Ensembl ENCODE 11 +93.0 93045 0.6 CTCF YY1 RAD21 PKNOX1 ZBTB33 TRIM22 MIR1252 HSALNG0092644 ENSG00000257894 PAWR SYT1
GH12J079514 Enhancer 0.4 Ensembl ENCODE 11 +95.9 95944 2 EP300 HSALNG0092644 MIR1252 ENSG00000257894 PAWR SYT1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR1252 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR1252 Gene

Latest Assembly
chr12:79,419,257-79,419,321
(GRCh38/hg38)
Size:
65 bases
Orientation:
Plus strand

Previous Assembly
chr12:79,813,037-79,813,101
(GRCh37/hg19 by Entrez Gene)
Size:
65 bases
Orientation:
Plus strand

chr12:79,813,037-79,813,101
(GRCh37/hg19 by Ensembl)
Size:
65 bases
Orientation:
Plus strand

Genomic View for MIR1252 Gene

Genes around MIR1252 on UCSC Golden Path with GeneCards custom track
MIR1252 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR1252 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1252 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1252 Gene

Proteins for MIR1252 Gene

Post-translational modifications for MIR1252 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1252 Gene

Domains & Families for MIR1252 Gene

Gene Families for MIR1252 Gene

HGNC:
genes like me logo Genes that share domains with MIR1252: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1252 Gene

Function for MIR1252 Gene

Phenotypes From GWAS Catalog for MIR1252 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1252 Gene

Localization for MIR1252 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1252 Gene

Pathways & Interactions for MIR1252 Gene

PathCards logo

SuperPathways for MIR1252 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR1252 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR1252 Gene

Drugs & Compounds for MIR1252 Gene

No Compound Related Data Available

Transcripts for MIR1252 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR1252 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075CAE4_9606 precursor_RNA 65 3

RefSeq: NR_031700,

Ensembl: ENST00000408861 (view in UCSC) ,

miRBase: MI0006434,

URS000075C0BE_9606 miRNA 22 3

RefSeq: NR_031700,

miRBase: MIMAT0005944,

MirGeneDB: Hsa-Mir-1252_5p,

URS000075D86C_9606 miRNA 22 2

RefSeq: NR_031700,

miRBase: MIMAT0026744,

URS0000EFE15F_9606 precursor_RNA 60 1

MirGeneDB: Hsa-Mir-1252,

URS0000EFD036_9606 miRNA 22 1

MirGeneDB: Hsa-Mir-1252_3p,

MIR1252 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1252 Gene

No ASD Table

Relevant External Links for MIR1252 Gene

GeneLoc Exon Structure for
MIR1252

No data available for mRNA/cDNA for MIR1252 Gene

Expression for MIR1252 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR1252

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1252 Gene

Orthologs for MIR1252 Gene

Evolution for MIR1252 Gene

ENSEMBL:
Gene Tree for MIR1252 (if available)
TreeFam:
Gene Tree for MIR1252 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR1252

No data available for Orthologs for MIR1252 Gene

Paralogs for MIR1252 Gene

No data available for Paralogs for MIR1252 Gene

Variants for MIR1252 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR1252 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR1252 Gene

Variant ID Type Subtype PubMed ID
nsv832467 CNV loss 17160897

Additional Variant Information for MIR1252 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1252
Leiden Open Variation Database (LOVD)
MIR1252

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR1252 Gene

Disorders for MIR1252 Gene

Additional Disease Information for MIR1252

No disorders were found for MIR1252 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1252 Gene

Publications for MIR1252 Gene

  1. The LncRNA AL161431.1 targets miR-1252-5p and facilitates cellular proliferation and migration via MAPK signaling in endometrial carcinoma. (PMID: 32196580) Gu ZR … Liu W (European review for medical and pharmacological sciences 2020) 3
  2. CircABCB10 promotes nonsmall cell lung cancer cell proliferation and migration by regulating the miR-1252/FOXR2 axis. (PMID: 30417418) Tian X … Yang W (Journal of cellular biochemistry 2019) 3
  3. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J … Kaessmann H (Genome research 2013) 3
  4. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR1252 Gene

Sources for MIR1252 Gene