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Aliases for MIR1251 Gene

Subcategory (RNA class) for MIR1251 Gene


Quality Score for this RNA gene is


Aliases for MIR1251 Gene

  • MicroRNA 1251 2 3 5
  • Hsa-Mir-1251 3
  • MIRN1251 3

External Ids for MIR1251 Gene

Previous HGNC Symbols for MIR1251 Gene

  • MIRN1251

Previous GeneCards Identifiers for MIR1251 Gene

  • GC00U923021
  • GC12P096410
  • GC12P097885

Summaries for MIR1251 Gene

Entrez Gene Summary for MIR1251 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1251 Gene

MIR1251 (MicroRNA 1251) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1251 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1251 Gene

Genomics for MIR1251 Gene

GeneHancer (GH) Regulatory Elements for MIR1251 Gene

Promoters and enhancers for MIR1251 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12I097565 Enhancer 1.2 ENCODE dbSUPER 10.2 +77.9 77903 7.8 PKNOX1 CLOCK FOXA2 MLX ARID4B NEUROD1 ZNF48 ETS1 YY1 ELK1 RMST MIR1251 ENSG00000277081 ENSG00000257157
GH12I097464 Enhancer 0.7 Ensembl ENCODE 11.6 -26.7 -26704 2.3 SP1 POLR2A POU5F1 SIN3A REST MIR1251 RMST GC12P097473
GH12I097536 Enhancer 0.5 dbSUPER 10.4 +45.9 45853 2.4 ZNF217 CTBP1 JUND GATA3 FOXA2 DPF2 FOXA1 MIR135A2 MIR1251 RMST ENSG00000274819 ENSG00000251844
GH12I097535 Enhancer 0.5 dbSUPER 9.9 +43.8 43798 1.2 ZNF217 GATA3 DPF2 CEBPG FOXA1 MIR135A2 MIR1251 RMST ENSG00000274819 ENSG00000251844
GH12I097534 Enhancer 0.4 dbSUPER 9.9 +42.8 42784 0.7 ZNF316 MAFK MIR135A2 MIR1251 RMST ENSG00000274819 ENSG00000251844
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1251 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1251 Gene

Genomic Locations for MIR1251 Gene
70 bases
Plus strand

Genomic View for MIR1251 Gene

Genes around MIR1251 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1251 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1251 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1251 Gene

Proteins for MIR1251 Gene

Post-translational modifications for MIR1251 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1251 Gene

Domains & Families for MIR1251 Gene

Gene Families for MIR1251 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1251: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1251 Gene

Function for MIR1251 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1251 Gene

Localization for MIR1251 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1251 Gene

Pathways & Interactions for MIR1251 Gene

SuperPathways for MIR1251 Gene

No Data Available

Interacting Proteins for MIR1251 Gene

Gene Ontology (GO) - Biological Process for MIR1251 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1251 Gene

Drugs & Compounds for MIR1251 Gene

No Compound Related Data Available

Transcripts for MIR1251 Gene

mRNA/cDNA for MIR1251 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1251 Gene

No ASD Table

Relevant External Links for MIR1251 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1251 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1251 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1251 Gene:

genes like me logo Genes that share expression patterns with MIR1251: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1251 Gene

Orthologs for MIR1251 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR1251 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Mir1251 34
  • 100 (a)
(Pan troglodytes)
Mammalia ptr-mir-1251 34
  • 100 (a)
(Bos Taurus)
Mammalia bta-mir-1251 34
  • 99 (a)
(Canis familiaris)
Mammalia -- 34
  • 99 (a)
(Monodelphis domestica)
Mammalia mdo-mir-1251 34
  • 89 (a)
Species where no ortholog for MIR1251 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1251 Gene

Gene Tree for MIR1251 (if available)
Gene Tree for MIR1251 (if available)

Paralogs for MIR1251 Gene

No data available for Paralogs for MIR1251 Gene

Variants for MIR1251 Gene

Sequence variations from dbSNP and Humsavar for MIR1251 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs1001435038 -- 97,492,441(+) G/A downstream_transcript_variant
rs1001804453 -- 97,490,704(+) A/G/T upstream_transcript_variant
rs1001870714 -- 97,491,123(+) A/G upstream_transcript_variant
rs1003110038 -- 97,491,030(+) A/T upstream_transcript_variant
rs1003851748 -- 97,491,359(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1251 Gene

Variant ID Type Subtype PubMed ID
nsv438229 CNV loss 16468122
nsv7234 OTHER inversion 18451855
nsv832495 CNV gain 17160897

Additional Variant Information for MIR1251 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1251 Gene

Disorders for MIR1251 Gene

Additional Disease Information for MIR1251

No disorders were found for MIR1251 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1251 Gene

Publications for MIR1251 Gene

  1. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J … Kaessmann H (Genome research 2013) 3 58
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 58
  3. Hidden layers of human small RNAs. (PMID: 18402656) Kawaji H … Hayashizaki Y (BMC genomics 2008) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR1251 Gene

Sources for MIR1251 Gene

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