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Aliases for MIR1249 Gene

Subcategory (RNA class) for MIR1249 Gene


Quality Score for this RNA gene is


Aliases for MIR1249 Gene

  • MicroRNA 1249 2 3 5
  • Hsa-Mir-1249 3
  • MIRN1249 3

External Ids for MIR1249 Gene

Previous HGNC Symbols for MIR1249 Gene

  • MIRN1249

Previous GeneCards Identifiers for MIR1249 Gene

  • GC00U922971
  • GC22M043976
  • GC22M045596

Summaries for MIR1249 Gene

Entrez Gene Summary for MIR1249 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1249 Gene

MIR1249 (MicroRNA 1249) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1249 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1249 Gene

Genomics for MIR1249 Gene

GeneHancer (GH) Regulatory Elements for MIR1249 Gene

Promoters and enhancers for MIR1249 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22I045200 Enhancer 0.6 ENCODE 550.8 -0.6 -578 2.6 ZBTB6 ZMYM3 GLI4 FOXA1 ZNF316 ZFP3 POLR2A ZFP36 FOS TRIM28 MIR1249 KIAA0930 NUP50-AS1 GC22P045213 GC22P045074 GC22M044704 GC22M045121
GH22I045201 Enhancer 0.2 ENCODE 550.8 +0.7 748 0 MIR1249 ENSG00000273353 KIAA0930 GC22P045074 GC22M044704 GC22M045121
GH22I045244 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 11.9 -46.3 -46306 5.6 PKNOX1 FOXA2 MLX ARID4B SIN3A ETS1 YY1 ELK1 ATF7 FOS ENSG00000273243 MIR1249 NUP50 NUP50-AS1 UPK3A RIBC2 SMC1B FAM118A LINC01589 KIAA0930
GH22I045224 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 12.4 -27.1 -27138 7.4 SOX13 MAX EBF1 CEBPG ZFHX2 POLR2A PRDM10 ATF7 E2F6 EGR2 KIAA0930 MIR1249 NUP50 NUP50-AS1 GC22P045213 GC22P045074 GC22M044704 GC22M045121
GH22I045267 Enhancer 1.3 Ensembl ENCODE dbSUPER 11.4 -68.3 -68261 2.8 RB1 ARID4B KLF17 SIN3A DMAP1 ZNF48 RAD21 ZNF335 GLIS2 EGR1 KIAA0930 MIR1249 RIBC2 SMC1B LINC01589 FAM118A RPS10P31 ENSG00000273287 GC22M044704 GC22P045074
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1249 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1249 Gene

Genomic Locations for MIR1249 Gene
66 bases
Minus strand

Genomic View for MIR1249 Gene

Genes around MIR1249 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1249 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1249 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1249 Gene

Proteins for MIR1249 Gene

Post-translational modifications for MIR1249 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1249 Gene

Domains & Families for MIR1249 Gene

Gene Families for MIR1249 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1249: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1249 Gene

Function for MIR1249 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1249 Gene

Localization for MIR1249 Gene

Gene Ontology (GO) - Cellular Components for MIR1249 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR1249: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR1249 Gene

Pathways & Interactions for MIR1249 Gene

SuperPathways for MIR1249 Gene

No Data Available

Interacting Proteins for MIR1249 Gene

Gene Ontology (GO) - Biological Process for MIR1249 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1249 Gene

Drugs & Compounds for MIR1249 Gene

No Compound Related Data Available

Transcripts for MIR1249 Gene

mRNA/cDNA for MIR1249 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1249 Gene

No ASD Table

Relevant External Links for MIR1249 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1249 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1249 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1249 Gene:

genes like me logo Genes that share expression patterns with MIR1249: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1249 Gene

Orthologs for MIR1249 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR1249 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-1249 34
  • 100 (a)
(Bos Taurus)
Mammalia bta-mir-1249 34
  • 95 (a)
(Mus musculus)
Mammalia Mir1249 34
  • 64 (a)
(Canis familiaris)
Mammalia -- 34
  • 53 (a)
Species where no ortholog for MIR1249 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1249 Gene

Gene Tree for MIR1249 (if available)
Gene Tree for MIR1249 (if available)

Paralogs for MIR1249 Gene

No data available for Paralogs for MIR1249 Gene

Variants for MIR1249 Gene

Sequence variations from dbSNP and Humsavar for MIR1249 Gene

SNP ID Clin Chr 22 pos Variation AA Info Type
rs1000875930 -- 45,201,516(-) G/A/C/T upstream_transcript_variant
rs1001156348 -- 45,201,752(-) C/A/G upstream_transcript_variant
rs1005913582 -- 45,201,139(-) G/A upstream_transcript_variant
rs1007837500 -- 45,200,460(-) C/T downstream_transcript_variant
rs1008482025 -- 45,202,719(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1249 Gene

Variant ID Type Subtype PubMed ID
nsv834220 CNV loss 17160897
nsv829278 CNV loss 20364138
esv2758843 CNV gain 17122850

Additional Variant Information for MIR1249 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1249 Gene

Disorders for MIR1249 Gene

Additional Disease Information for MIR1249

No disorders were found for MIR1249 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1249 Gene

Publications for MIR1249 Gene

  1. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR1249 Gene

Sources for MIR1249 Gene

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