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Aliases for MIR1246 Gene

Subcategory (RNA class) for MIR1246 Gene


Quality Score for this RNA gene is


Aliases for MIR1246 Gene

  • MicroRNA 1246 2 3 5
  • Hsa-Mir-1246 3
  • MIRN1246 3

External Ids for MIR1246 Gene

Previous HGNC Symbols for MIR1246 Gene

  • MIRN1246

Previous GeneCards Identifiers for MIR1246 Gene

  • GC00U922927
  • GC02M177173
  • GC02M177466

Summaries for MIR1246 Gene

Entrez Gene Summary for MIR1246 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1246 Gene

MIR1246 (MicroRNA 1246) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1246 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1246 Gene

Genomics for MIR1246 Gene

GeneHancer (GH) Regulatory Elements for MIR1246 Gene

Promoters and enhancers for MIR1246 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I176613 Enhancer 0.3 ENCODE 0.4 -12.6 -12618 0.3 PRDM6 LOC105373754 MIR1246
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1246 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1246 Gene

Genomic Locations for MIR1246 Gene
73 bases
Minus strand

Genomic View for MIR1246 Gene

Genes around MIR1246 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1246 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1246 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1246 Gene

Proteins for MIR1246 Gene

Post-translational modifications for MIR1246 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1246 Gene

Domains & Families for MIR1246 Gene

Gene Families for MIR1246 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1246: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1246 Gene

Function for MIR1246 Gene

Phenotypes From GWAS Catalog for MIR1246 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1246 Gene

Localization for MIR1246 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1246 Gene

Pathways & Interactions for MIR1246 Gene

SuperPathways for MIR1246 Gene

No Data Available

Interacting Proteins for MIR1246 Gene

Gene Ontology (GO) - Biological Process for MIR1246 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1246 Gene

Drugs & Compounds for MIR1246 Gene

No Compound Related Data Available

Transcripts for MIR1246 Gene

mRNA/cDNA for MIR1246 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1246 Gene

No ASD Table

Relevant External Links for MIR1246 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1246 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1246 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1246 Gene

Orthologs for MIR1246 Gene

Evolution for MIR1246 Gene

Gene Tree for MIR1246 (if available)
Gene Tree for MIR1246 (if available)

No data available for Orthologs for MIR1246 Gene

Paralogs for MIR1246 Gene

No data available for Paralogs for MIR1246 Gene

Variants for MIR1246 Gene

Sequence variations from dbSNP and Humsavar for MIR1246 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000005568 -- 176,602,679(-) T/C upstream_transcript_variant
rs1000057821 -- 176,602,991(-) C/G/T upstream_transcript_variant
rs1001904953 -- 176,601,911(-) C/T upstream_transcript_variant
rs1002494806 -- 176,600,591(-) C/G downstream_transcript_variant
rs1007915427 -- 176,602,909(-) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1246 Gene

Variant ID Type Subtype PubMed ID
nsv834464 CNV gain 17160897
esv3593451 CNV loss 21293372

Additional Variant Information for MIR1246 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1246 Gene

Disorders for MIR1246 Gene

Additional Disease Information for MIR1246

No disorders were found for MIR1246 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1246 Gene

Publications for MIR1246 Gene

  1. Exosomal microRNA concentrations in colorectal cancer: A mathematical model. (PMID: 27993628) Lai X … Friedman A (Journal of theoretical biology 2017) 3 58
  2. Octamer 4/microRNA-1246 signaling axis drives Wnt/β-catenin activation in liver cancer stem cells. (PMID: 27639189) Chai S … Ma S (Hepatology (Baltimore, Md.) 2016) 3 58
  3. Extracellular miR-1246 promotes lung cancer cell proliferation and enhances radioresistance by directly targeting DR5. (PMID: 27129166) Yuan D … Shao C (Oncotarget 2016) 3 58
  4. Early-phase circulating miRNAs predict tumor recurrence and survival of hepatocellular carcinoma patients after liver transplantation. (PMID: 26918346) Ng KT … Man K (Oncotarget 2016) 3 58
  5. Hsa-miR-1246 and hsa-miR-1290 are associated with stemness and invasiveness of non-small cell lung cancer. (PMID: 26711929) Kim G … Jeong HC (Lung cancer (Amsterdam, Netherlands) 2016) 3 58

Products for MIR1246 Gene

Sources for MIR1246 Gene

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