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Aliases for MIR1245A Gene

Subcategory (RNA class) for MIR1245A Gene


Quality Score for this RNA gene is


Aliases for MIR1245A Gene

  • MicroRNA 1245a 2 3 5
  • MicroRNA 1245 2 3
  • Hsa-Mir-1245a 3
  • Hsa-Mir-1245 3
  • Mir-1245a 3
  • MIRN1245 3
  • MIR1245 3

External Ids for MIR1245A Gene

Previous HGNC Symbols for MIR1245A Gene

  • MIRN1245
  • MIR1245

Previous GeneCards Identifiers for MIR1245A Gene

  • GC02P189843

Summaries for MIR1245A Gene

Entrez Gene Summary for MIR1245A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1245A Gene

MIR1245A (MicroRNA 1245a) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1245A Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1245A Gene

Genomics for MIR1245A Gene

GeneHancer (GH) Regulatory Elements for MIR1245A Gene

Promoters and enhancers for MIR1245A Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I188969 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 550.8 +0.1 112 18.2 PKNOX1 BMI1 YBX1 BATF RAD21 ZNF366 ZNF143 RCOR1 ATF7 IKZF2 MIR1245A MIR1245B COL3A1 ENSG00000273240 LOC105373791
GH02I189002 Enhancer 0.6 ENCODE 11 +24.7 24735 1.6 GATA3 JUND POLR2A JUN CREB1 FOSL2 FOS CUX1 EP300 MIR1245A MIR3606 COL3A1 ENSG00000228073
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1245A on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1245A Gene

Genomic Locations for MIR1245A Gene
70 bases
Plus strand

Genomic View for MIR1245A Gene

Genes around MIR1245A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1245A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1245A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1245A Gene

Proteins for MIR1245A Gene

Post-translational modifications for MIR1245A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1245A Gene

Domains & Families for MIR1245A Gene

Gene Families for MIR1245A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1245A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1245A Gene

Function for MIR1245A Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1245A Gene

Localization for MIR1245A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1245A Gene

Pathways & Interactions for MIR1245A Gene

SuperPathways for MIR1245A Gene

No Data Available

Interacting Proteins for MIR1245A Gene

Gene Ontology (GO) - Biological Process for MIR1245A Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1245A Gene

Drugs & Compounds for MIR1245A Gene

No Compound Related Data Available

Transcripts for MIR1245A Gene

mRNA/cDNA for MIR1245A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1245A Gene

No ASD Table

Relevant External Links for MIR1245A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1245A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1245A Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1245A Gene

Orthologs for MIR1245A Gene

Evolution for MIR1245A Gene

Gene Tree for MIR1245A (if available)
Gene Tree for MIR1245A (if available)

No data available for Orthologs for MIR1245A Gene

Paralogs for MIR1245A Gene

No data available for Paralogs for MIR1245A Gene

Variants for MIR1245A Gene

Sequence variations from dbSNP and Humsavar for MIR1245A Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1001009730 -- 188,976,180(+) A/G upstream_transcript_variant
rs1001061743 -- 188,976,397(+) T/C upstream_transcript_variant
rs1002514424 -- 188,977,845(+) A/G upstream_transcript_variant
rs1002976932 -- 188,978,153(+) A/G non_coding_transcript_variant
rs1005694686 -- 188,977,837(+) G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1245A Gene

Variant ID Type Subtype PubMed ID
dgv7233n54 CNV loss 21841781
dgv7234n54 CNV loss 21841781
nsv459992 CNV loss 19166990

Additional Variant Information for MIR1245A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1245A Gene

Disorders for MIR1245A Gene

Additional Disease Information for MIR1245A

No disorders were found for MIR1245A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1245A Gene

Publications for MIR1245A Gene

  1. Human microRNA-1245 down-regulates the NKG2D receptor in natural killer cells and impairs NKG2D-mediated functions. (PMID: 22491735) Espinoza JL … Nakao S (Haematologica 2012) 3 58
  2. Up-regulation of miR-1245 by c-myc targets BRCA2 and impairs DNA repair. (PMID: 22158906) Song L … Li J (Journal of molecular cell biology 2012) 3 58
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  4. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 58
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR1245A Gene

Sources for MIR1245A Gene

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