microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1238 Gene

Subcategory (RNA class) for MIR1238 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR1238 Gene

  • MicroRNA 1238 2 3 5
  • Hsa-Mir-1238 2 3
  • MIR1238 2 5
  • MIMAT0005593 50
  • MIMAT0022947 50
  • MI0006328 50
  • MIRN1238 3

External Ids for MIR1238 Gene

Previous HGNC Symbols for MIR1238 Gene

  • MIRN1238

Previous GeneCards Identifiers for MIR1238 Gene

  • GC00U922934
  • GC19P010525
  • GC19P010664

Summaries for MIR1238 Gene

Entrez Gene Summary for MIR1238 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1238 Gene

MIR1238 (MicroRNA 1238) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1238 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1238 Gene

Genomics for MIR1238 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR1238 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J010551 Enhancer 1.2 Ensembl ENCODE dbSUPER 600.7 +1.8 1783 5.8 CTCF POLR2A FOXA1 ZIC2 RBFOX2 PKNOX1 PATZ1 TCF12 ZNF600 ZNF341 MIR1238 KRI1 CDKN2D SLC44A2 ILF3 AP1M2 RF00066-093 RNU7-140P lnc-CDKN2D-1 ATG4D
GH19J010514 Promoter/Enhancer 2 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 12 -34.9 -34906 5.2 HNRNPL PRDM10 ZNF629 IKZF1 KDM1A ZIC2 ZSCAN4 PATZ1 ZNF501 EZH2 S1PR5 LOC100419831 ILF3 KRI1 QTRT1 ATG4D ZNF846 CDKN2D SLC44A2 ZNF562
GH19J010515 Enhancer 0.6 ENCODE dbSUPER 12 -37.8 -37802 0.2 CTCF TEAD4 EZH2 ZBTB33 NRF1 POLR2A lnc-KEAP1-1 ATG4D KRI1 CDKN2D MIR1238 RNU7-140P ILF3 SLC44A2 S1PR5 KEAP1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR1238 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR1238 Gene

Genomic Locations for MIR1238 Gene
chr19:10,552,122-10,552,204
(GRCh38/hg38)
Size:
83 bases
Orientation:
Plus strand
chr19:10,662,798-10,662,880
(GRCh37/hg19)
Size:
83 bases
Orientation:
Plus strand

Genomic View for MIR1238 Gene

Genes around MIR1238 on UCSC Golden Path with GeneCards custom track
MIR1238 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR1238 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1238 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1238 Gene

Proteins for MIR1238 Gene

Post-translational modifications for MIR1238 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1238 Gene

Domains & Families for MIR1238 Gene

Gene Families for MIR1238 Gene

HGNC:
genes like me logo Genes that share domains with MIR1238: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1238 Gene

Function for MIR1238 Gene

Phenotypes From GWAS Catalog for MIR1238 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1238 Gene

Localization for MIR1238 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1238 Gene

Pathways & Interactions for MIR1238 Gene

PathCards logo

SuperPathways for MIR1238 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR1238 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR1238 Gene

Drugs & Compounds for MIR1238 Gene

No Compound Related Data Available

Transcripts for MIR1238 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR1238 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075A0EE_9606 precursor_RNA 83 4

HGNC: 33933,

RefSeq: NR_031603,

Ensembl: ENST00000408483 (view in UCSC) ,

miRBase: MI0006328,

URS000075EC66_9606 miRNA 23 2

RefSeq: NR_031603,

miRBase: MIMAT0022947,

URS000075E57E_9606 miRNA 20 2

RefSeq: NR_031603,

miRBase: MIMAT0005593,

MIR1238 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1238 Gene

No ASD Table

Relevant External Links for MIR1238 Gene

GeneLoc Exon Structure for
MIR1238

No data available for mRNA/cDNA for MIR1238 Gene

Expression for MIR1238 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1238 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR1238

genes like me logo Genes that share expression patterns with MIR1238: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1238 Gene

Orthologs for MIR1238 Gene

Evolution for MIR1238 Gene

ENSEMBL:
Gene Tree for MIR1238 (if available)
TreeFam:
Gene Tree for MIR1238 (if available)

No data available for Orthologs for MIR1238 Gene

Paralogs for MIR1238 Gene

No data available for Paralogs for MIR1238 Gene

Variants for MIR1238 Gene

Additional dbSNP identifiers (rs#s) for MIR1238 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1238 Gene

Variant ID Type Subtype PubMed ID
nsv833744 CNV loss 17160897
nsv833745 CNV loss 17160897

Additional Variant Information for MIR1238 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1238

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR1238 Gene

Disorders for MIR1238 Gene

Additional Disease Information for MIR1238

No disorders were found for MIR1238 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1238 Gene

Publications for MIR1238 Gene

  1. Upregulated circular RNA circ_0070934 facilitates cutaneous squamous cell carcinoma cell growth and invasion by sponging miR-1238 and miR-1247-5p. (PMID: 30967263) An X … Li C (Biochemical and biophysical research communications 2019) 3
  2. Elevation of circular RNA circ_0005230 facilitates cell growth and metastasis via sponging miR-1238 and miR-1299 in cholangiocarcinoma. (PMID: 30946694) Xu Y … Cui Y (Aging 2019) 3
  3. Exosomal transfer of miR-1238 contributes to temozolomide-resistance in glioblastoma. (PMID: 30917935) Yin J … You Y (EBioMedicine 2019) 3
  4. Altered Expressions of miR-1238-3p, miR-494, miR-6069, and miR-139-3p in the Formation of Chronic Brucellosis. (PMID: 27722176) Budak F … Oral HB (Journal of immunology research 2016) 3
  5. miR-1238 inhibits cell proliferation by targeting LHX2 in non-small cell lung cancer. (PMID: 26189214) Shi X … Zhang HT (Oncotarget 2015) 3

Products for MIR1238 Gene

Sources for MIR1238 Gene