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Aliases for MIR1237 Gene

Subcategory (RNA class) for MIR1237 Gene


Quality Score for this RNA gene is


Aliases for MIR1237 Gene

  • MicroRNA 1237 2 3 5
  • Hsa-Mir-1237 3
  • MIRN1237 3

External Ids for MIR1237 Gene

Previous HGNC Symbols for MIR1237 Gene

  • MIRN1237

Previous GeneCards Identifiers for MIR1237 Gene

  • GC00U922958
  • GC11P063894
  • GC11P064136

Summaries for MIR1237 Gene

Entrez Gene Summary for MIR1237 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1237 Gene

MIR1237 (MicroRNA 1237) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR1237 include Spinal Chordoma.

Additional gene information for MIR1237 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1237 Gene

Genomics for MIR1237 Gene

Regulatory Elements for MIR1237 Gene

Enhancers for MIR1237 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H064438 0.9 FANTOM5 ENCODE 11.2 +70.5 70512 1.3 ZNF217 SMARCE1 ZNF121 CTBP1 MTA1 HNF4A DPF2 SLC22A12 NRXN2 SLC22A11 MIR1237 OTUB1 GC11P064445 ENSG00000231492
GH11H064394 0.8 Ensembl ENCODE 12.1 +27.2 27166 2.3 HINFP ZIC2 ZBTB20 NR2F2 ENSG00000231680 RPS6KA4 MIR1237 LOC100996455 NRXN2 TRMT112 CCDC88B GC11M064381
GH11H064501 0.9 ENCODE 10.7 +133.6 133619 1.9 HDGF ZFP64 RARA TCF12 RCOR1 THAP11 SP5 ZEB2 SMARCA4 CEBPA ENSG00000237410 NRXN2 SLC22A11 SLC22A12 MIR1237 LOC100996455 LOC105369342 ENSG00000237363
GH11H064347 0.8 ENCODE 11.9 -20.2 -20221 1.9 BCOR KLF1 JUN CHD4 ZMYM3 MAX CEBPG POLR2A FOXK2 PATZ1 LOC102723878 MIR1237 PRDX5 TRMT112 ESRRA CATSPERZ ENSG00000207024 KCNK4 KCNK4-TEX40 BAD
GH11H064489 0.8 ENCODE 10.5 +121.4 121422 0.2 CTCF MXI1 ATF1 RB1 MAX BMI1 RAD21 ZKSCAN1 CC2D1A MTA3 NRXN2 LOC100996455 SLC22A12 MIR1237 LOC105369342 GC11M064457
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1237 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1237 Gene

Genomic Locations for MIR1237 Gene
102 bases
Plus strand

Genomic View for MIR1237 Gene

Genes around MIR1237 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1237 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1237 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1237 Gene

Proteins for MIR1237 Gene

Post-translational modifications for MIR1237 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1237 Gene

Domains & Families for MIR1237 Gene

Gene Families for MIR1237 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1237: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1237 Gene

Function for MIR1237 Gene

Phenotypes From GWAS Catalog for MIR1237 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1237 Gene

Localization for MIR1237 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1237 Gene

Pathways & Interactions for MIR1237 Gene

SuperPathways for MIR1237 Gene

No Data Available

Interacting Proteins for MIR1237 Gene

Gene Ontology (GO) - Biological Process for MIR1237 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1237 Gene

Drugs & Compounds for MIR1237 Gene

No Compound Related Data Available

Transcripts for MIR1237 Gene

mRNA/cDNA for MIR1237 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1237 Gene

No ASD Table

Relevant External Links for MIR1237 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1237 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1237 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1237 Gene:

genes like me logo Genes that share expression patterns with MIR1237: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1237 Gene

Orthologs for MIR1237 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR1237 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-1237 34
  • 100 (a)
Species where no ortholog for MIR1237 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1237 Gene

Gene Tree for MIR1237 (if available)
Gene Tree for MIR1237 (if available)

Paralogs for MIR1237 Gene

No data available for Paralogs for MIR1237 Gene

Variants for MIR1237 Gene

Sequence variations from dbSNP and Humsavar for MIR1237 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1001605310 -- 64,367,366(+) AGTGC(A/G)ATGGC intron-variant, upstream-variant-2KB
rs1002361819 -- 64,368,321(+) CGGGG(A/G)CTCTA intron-variant, upstream-variant-2KB
rs1004105434 -- 64,367,274(+) CCCAA(C/T)AGCTA intron-variant, upstream-variant-2KB
rs1004323380 -- 64,366,960(+) ACATT(C/T)CATTC intron-variant, upstream-variant-2KB
rs1005554008 -- 64,368,354(+) GCAGC(A/G)TGAGC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1237 Gene

Variant ID Type Subtype PubMed ID
nsv832187 CNV loss 17160897
nsv832186 CNV loss 17160897

Relevant External Links for MIR1237 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1237 Gene

Disorders for MIR1237 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR1237 Gene - From: GeneCards

Disorder Aliases PubMed IDs
spinal chordoma
  • chordoma of spine
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR1237

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR1237: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR1237 Gene

Publications for MIR1237 Gene

  1. Reduced expression of miRNA-1237-3p associated with poor survival of spinal chordoma patients. (PMID: 25850393) Zou MX … Deng YW (European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 2015) 3 60
  2. Epigenetically silenced microRNAs in gastric cancer: Functional analysis and identification of their target genes. (PMID: 26043902) Bae JH … Yi JM (Oncology reports 2015) 3 60
  3. Mammalian mirtron genes. (PMID: 17964270) Berezikov E … Lai EC (Molecular cell 2007) 3 60
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR1237 Gene

Sources for MIR1237 Gene

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