microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1234 Gene

Data sources for MIR1234 Gene:

RNA type for MIR1234 Gene

miRNA

Aliases for MIR1234 Gene

External Ids for MIR1234 Gene

Previous HGNC Symbols for MIR1234 Gene

  • MIRN1234

Previous GeneCards Identifiers for MIR1234 Gene

  • GC00U923039
  • GC08M145598
  • GC08M145625
  • GC08M144401
  • GC08M144406

Summaries for MIR1234 Gene

Entrez Gene Summary for MIR1234 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1234 Gene

MIR1234 (MicroRNA 1234) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Processing of Capped Intronless Pre-mRNA and Tat-mediated elongation of the HIV-1 transcript.

Additional gene information for MIR1234 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1234 Gene

Genomics for MIR1234 Gene

Genomic Locations for MIR1234 Gene

Latest Assembly
chr8:144,400,086-144,400,165
(GRCh38/hg38)
Size:
80 bases
Orientation:
Minus strand

Alternative Locations (GRCh38/hg38)

  • chr8(PATCHES):130,689-130,768 (-)

Genomic View for MIR1234 Gene

Genes around MIR1234 on UCSC Golden Path with GeneCards custom track
MIR1234 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR1234 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1234 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1234 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR1234 Gene

Proteins for MIR1234 Gene

Post-translational modifications for MIR1234 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1234 Gene

Domains & Families for MIR1234 Gene

Gene Families for MIR1234 Gene

HGNC:
genes like me logo Genes that share domains with MIR1234: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1234 Gene

Function for MIR1234 Gene

Phenotypes From GWAS Catalog for MIR1234 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1234 Gene

Localization for MIR1234 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR1234 gene
Compartment Confidence
extracellular 1
nucleus 1

Gene Ontology (GO) - Cellular Components for MIR1234 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070062 extracellular exosome IDA 31926946
genes like me logo Genes that share ontologies with MIR1234: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for MIR1234 Gene

Pathways & Interactions for MIR1234 Gene

genes like me logo Genes that share pathways with MIR1234: view

Pathways by source for MIR1234 Gene

Gene Ontology (GO) - Biological Process for MIR1234 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR1234 Gene

Drugs & Compounds for MIR1234 Gene

No Compound Related Data Available

Transcripts for MIR1234 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR1234 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS00007E4877_9606 pre_miRNA 80 3

RefSeq: NR_031600,

Ensembl: ENST00000579254 (view in UCSC) ,

miRBase: MI0006324,

URS000075E194_9606 miRNA 22 3

RefSeq: NR_031600,

miRBase: MIMAT0005589,

TarBase: hsa-miR-1234-3p,

MIR1234 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1234 Gene

No ASD Table

Relevant External Links for MIR1234 Gene

GeneLoc Exon Structure for
MIR1234

No data available for mRNA/cDNA for MIR1234 Gene

Expression for MIR1234 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1234 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR1234

genes like me logo Genes that share expression patterns with MIR1234: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1234 Gene

Orthologs for MIR1234 Gene

Evolution for MIR1234 Gene

ENSEMBL:
Gene Tree for MIR1234 (if available)
TreeFam:
Gene Tree for MIR1234 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR1234

No data available for Orthologs for MIR1234 Gene

Paralogs for MIR1234 Gene

No data available for Paralogs for MIR1234 Gene

Variants for MIR1234 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR1234 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR1234 Gene

Variant ID Type Subtype PubMed ID
dgv3080n100 CNV gain 25217958
dgv3081n100 CNV gain 25217958
esv2422420 CNV duplication 17116639
esv2758673 CNV gain 17122850
esv3582465 CNV loss 25503493
nsv1064415 CNV gain 25217958
nsv1118744 CNV deletion 24896259
nsv509644 CNV insertion 20534489
nsv827852 CNV gain 20364138
nsv833332 CNV loss 17160897
nsv833333 CNV loss 17160897
nsv9489 CNV gain 18304495
nsv952096 CNV deletion 24416366

Additional Variant Information for MIR1234 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1234
Leiden Open Variation Database (LOVD)
MIR1234

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR1234 Gene

Disorders for MIR1234 Gene

Additional Disease Information for MIR1234

No disorders were found for MIR1234 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1234 Gene

Publications for MIR1234 Gene

  1. Exosomal miR-146a-5p from Treponema pallidum-stimulated macrophages reduces endothelial cells permeability and monocyte transendothelial migration by targeting JAM-C. (PMID: 31926946) Hu W … Zhang R (Experimental cell research 2020) 3
  2. Expression of microRNA-1234 related signal transducer and activator of transcription 3 in patients with diffuse large B-cell lymphoma of activated B-cell like type from high and low infectious disease areas. (PMID: 23841503) Högfeldt T … Moshfegh A (Leukemia & lymphoma 2014) 3
  3. Mammalian mirtron genes. (PMID: 17964270) Berezikov E … Lai EC (Molecular cell 2007) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR1234 Gene

Sources for MIR1234 Gene