microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1233-2 Gene

Subcategory (RNA class) for MIR1233-2 Gene


Quality Score for this RNA gene is


Aliases for MIR1233-2 Gene

  • MicroRNA 1233-2 2 3 5
  • Hsa-Mir-1233-2 3
  • MIMAT0022943 53
  • MIMAT0005588 53
  • MI0015973 53
  • MIR1233-2 2
  • MIR1233-1 2
  • MI0006323 53

External Ids for MIR1233-2 Gene

Previous GeneCards Identifiers for MIR1233-2 Gene

  • GC15U901214
  • GC15M034821
  • GC15M034824
  • GC15M034833

Summaries for MIR1233-2 Gene

Entrez Gene Summary for MIR1233-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1233-2 Gene

MIR1233-2 (MicroRNA 1233-2) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1233-2 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1233-2 Gene

Genomics for MIR1233-2 Gene

Genomic Locations for MIR1233-2 Gene

Genomic Locations for MIR1233-2 Gene
82 bases
Minus strand
82 bases
Minus strand

Genomic View for MIR1233-2 Gene

Genes around MIR1233-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1233-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1233-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1233-2 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR1233-2 Gene

Proteins for MIR1233-2 Gene

Post-translational modifications for MIR1233-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1233-2 Gene

Domains & Families for MIR1233-2 Gene

Gene Families for MIR1233-2 Gene

genes like me logo Genes that share domains with MIR1233-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1233-2 Gene

Function for MIR1233-2 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1233-2 Gene

Localization for MIR1233-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1233-2 Gene

Pathways & Interactions for MIR1233-2 Gene

PathCards logo

SuperPathways for MIR1233-2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR1233-2 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1233-2 Gene

Drugs & Compounds for MIR1233-2 Gene

No Compound Related Data Available

Transcripts for MIR1233-2 Gene

mRNA/cDNA for MIR1233-2 Gene

(2) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNACentral transcripts :
(4) miRBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1233-2 Gene

No ASD Table

Relevant External Links for MIR1233-2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1233-2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1233-2 Gene

genes like me logo Genes that share expression patterns with MIR1233-2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1233-2 Gene

Orthologs for MIR1233-2 Gene

Evolution for MIR1233-2 Gene

Gene Tree for MIR1233-2 (if available)
Gene Tree for MIR1233-2 (if available)

No data available for Orthologs for MIR1233-2 Gene

Paralogs for MIR1233-2 Gene

No data available for Paralogs for MIR1233-2 Gene

Variants for MIR1233-2 Gene

Sequence variations from dbSNP and Humsavar for MIR1233-2 Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1041928323 -- 34,530,238(-) G/A upstream_transcript_variant
rs111260224 -- 34,530,335(-) A/C upstream_transcript_variant
rs1157402084 -- 34,528,268(-) T/C downstream_transcript_variant
rs1157813788 -- 34,528,084(-) G/A downstream_transcript_variant
rs1159827971 -- 34,527,959(-) T/C downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1233-2 Gene

Variant ID Type Subtype PubMed ID
dgv107n111 CNV duplication 26073780
dgv21e213 CNV loss 24956385
dgv22e213 CNV gain 24956385
dgv2550n100 CNV gain 25217958
dgv2551n100 CNV gain 25217958
dgv2552n100 CNV gain 25217958
dgv2553n100 CNV loss 25217958
dgv2554n100 CNV loss 25217958
dgv2557n100 CNV loss 25217958
dgv2558n100 CNV gain+loss 25217958
dgv2559n100 CNV gain+loss 25217958
dgv2562n100 CNV gain+loss 25217958
dgv2563n100 CNV loss 25217958
dgv2569n100 CNV loss 25217958
dgv2570n100 CNV loss 25217958
dgv2571n100 CNV gain 25217958
dgv2572n100 CNV gain 25217958
dgv2574n100 CNV loss 25217958
dgv302e201 CNV deletion 23290073
dgv313n27 CNV loss 19166990
dgv314n27 CNV gain 19166990
dgv43e203 CNV gain+loss 21179565
dgv4456n54 CNV gain 21841781
dgv4458n54 CNV loss 21841781
dgv4459n54 CNV loss 21841781
dgv4468n54 CNV loss 21841781
dgv4475n54 CNV gain 21841781
dgv4476n54 CNV loss 21841781
dgv4477n54 CNV loss 21841781
dgv4482n54 CNV loss 21841781
esv2751533 CNV loss 17911159
esv2760024 CNV gain+loss 17122850
esv27955 CNV gain+loss 19812545
esv33337 CNV gain+loss 17666407
esv3569431 CNV gain 25503493
esv3581626 CNV loss 25503493
esv3636115 CNV loss 21293372
esv3636116 CNV gain 21293372
esv3892664 CNV gain+loss 25118596
esv3892665 CNV loss 25118596
esv992827 CNV gain 20482838
nsv1039201 CNV gain 25217958
nsv1052620 CNV gain 25217958
nsv110 CNV deletion 15895083
nsv1160280 CNV deletion 26073780
nsv1160285 CNV duplication 26073780
nsv1485 CNV deletion 18451855
nsv428303 CNV gain 18775914
nsv442698 CNV gain+loss 18776908
nsv469547 CNV loss 16826518
nsv469685 CNV loss 16826518
nsv471236 CNV loss 18288195
nsv471682 CNV gain+loss 15918152
nsv482177 CNV gain 20164927
nsv509567 CNV insertion 20534489
nsv517751 CNV gain+loss 19592680
nsv568926 CNV gain 21841781
nsv569004 CNV gain+loss 21841781
nsv819187 CNV gain 19587683
nsv821682 CNV loss 15273396
nsv827290 CNV loss 20364138
nsv9241 CNV gain+loss 18304495
nsv974557 CNV duplication 23825009
nsv984049 CNV duplication 23825009

Additional Variant Information for MIR1233-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1233-2 Gene

Disorders for MIR1233-2 Gene

Additional Disease Information for MIR1233-2

No disorders were found for MIR1233-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1233-2 Gene

Publications for MIR1233-2 Gene

  1. A GDF15 3' UTR variant, rs1054564, results in allele-specific translational repression of GDF15 by hsa-miR-1233-3p. (PMID: 28806401) Teng MS … Ko YL (PloS one 2017) 3 56
  2. Serum microRNA-1233 is a specific biomarker for diagnosing acute pulmonary embolism. (PMID: 27150028) Kessler T … Sager HB (Journal of translational medicine 2016) 3 56
  3. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 56
  4. Mammalian mirtron genes. (PMID: 17964270) Berezikov E … Lai EC (Molecular cell 2007) 3 56
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

Products for MIR1233-2 Gene

Sources for MIR1233-2 Gene