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Aliases for MIR1229 Gene

Subcategory (RNA class) for MIR1229 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1229 Gene

  • MicroRNA 1229 2 3 5
  • Hsa-Mir-1229 3
  • MIRN1229 3

External Ids for MIR1229 Gene

Previous HGNC Symbols for MIR1229 Gene

  • MIRN1229

Previous GeneCards Identifiers for MIR1229 Gene

  • GC00U923116
  • GC05M179161
  • GC05M179225

Summaries for MIR1229 Gene

Entrez Gene Summary for MIR1229 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1229 Gene

MIR1229 (MicroRNA 1229) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1229 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1229 Gene

Genomics for MIR1229 Gene

GeneHancer (GH) Regulatory Elements for MIR1229 Gene

Promoters and enhancers for MIR1229 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05I179696 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 11.5 +99.4 99401 4.9 CLOCK FEZF1 DMAP1 IRF4 YY1 SLC30A9 E2F8 ZNF143 SP3 NFYC CANX GC05M179696 MAML1 HNRNPH1 ZNF354B RUFY1 MRNIP ZNF879 LOC101928445 ADAMTS2
GH05I179761 Enhancer 1.3 Ensembl ENCODE dbSUPER 13.5 +35.3 35311 2.9 HDGF PKNOX1 CLOCK ARID4B SIN3A ZNF2 GLIS2 GATA2 ZNF143 FOS MRNIP MAML1 ZNF879 LOC100996419 LTC4S MIR1229 SQSTM1 MGAT4B ZFP2 ZNF454
GH05I179764 Enhancer 1.2 Ensembl ENCODE dbSUPER 13.5 +32.5 32464 2.2 HDAC1 YY1 TCF12 FOS RXRA REST ZEB2 ZNF592 SMARCA4 IKZF1 MAML1 MGAT4B LTC4S MIR1229 SQSTM1 CBY3 MRNIP TBC1D9B CANX RNF130
GH05I179758 Enhancer 1.2 Ensembl ENCODE dbSUPER 13.5 +38.5 38546 2 HDGF PKNOX1 BATF ZNF121 ZNF366 FOS RCOR1 RUNX3 EGR2 ZNF280D MAML1 CANX LTC4S MIR1229 SQSTM1 MGAT4B HMGB3P22 CBY3 TBC1D9B MRNIP
GH05I179754 Enhancer 1.2 Ensembl ENCODE dbSUPER 13.4 +43.4 43410 1.4 ELF3 ARID4B RAD21 RARA THAP11 MIXL1 PAF1 RXRA CEBPB ELF1 MAML1 LTC4S MIR1229 MGAT4B SQSTM1 CBY3 CANX HMGB3P22 TBC1D9B MRNIP
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1229 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1229 Gene

Genomic Locations for MIR1229 Gene
chr5:179,798,278-179,798,346
(GRCh38/hg38)
Size:
69 bases
Orientation:
Minus strand
chr5:179,225,278-179,225,346
(GRCh37/hg19)

Genomic View for MIR1229 Gene

Genes around MIR1229 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1229 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1229 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1229 Gene

ORGUL Member Location for MIR1229 Gene

ORGUL Member Location for MIR1229 gene

Proteins for MIR1229 Gene

Post-translational modifications for MIR1229 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1229 Gene

Domains & Families for MIR1229 Gene

Gene Families for MIR1229 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1229: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1229 Gene

Function for MIR1229 Gene

Phenotypes From GWAS Catalog for MIR1229 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1229 Gene

Localization for MIR1229 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1229 Gene

Pathways & Interactions for MIR1229 Gene

SuperPathways for MIR1229 Gene

No Data Available

Interacting Proteins for MIR1229 Gene

Gene Ontology (GO) - Biological Process for MIR1229 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1229 Gene

Drugs & Compounds for MIR1229 Gene

No Compound Related Data Available

Transcripts for MIR1229 Gene

mRNA/cDNA for MIR1229 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1229 Gene

No ASD Table

Relevant External Links for MIR1229 Gene

GeneLoc Exon Structure for
MIR1229
ECgene alternative splicing isoforms for
MIR1229

Expression for MIR1229 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1229 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1229 Gene:

MIR1229
genes like me logo Genes that share expression patterns with MIR1229: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1229 Gene

Orthologs for MIR1229 Gene

Evolution for MIR1229 Gene

ENSEMBL:
Gene Tree for MIR1229 (if available)
TreeFam:
Gene Tree for MIR1229 (if available)

No data available for Orthologs for MIR1229 Gene

Paralogs for MIR1229 Gene

No data available for Paralogs for MIR1229 Gene

Variants for MIR1229 Gene

Sequence variations from dbSNP and Humsavar for MIR1229 Gene

SNP ID Clin Chr 05 pos Variation AA Info Type
rs1000000759 -- 179,798,720(-) C/A/T upstream_transcript_variant
rs1003748668 -- 179,799,376(-) G/T upstream_transcript_variant
rs10062634 -- 179,800,099(-) G/C upstream_transcript_variant
rs1008206168 -- 179,798,819(-) A/G upstream_transcript_variant
rs1008518467 -- 179,799,738(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1229 Gene

Variant ID Type Subtype PubMed ID
nsv823361 CNV loss 20364138
nsv600661 CNV loss 21841781
nsv600660 CNV loss 21841781
nsv600659 CNV loss 21841781
nsv518964 CNV loss 19592680
nsv469579 CNV loss 16826518
dgv10241n54 CNV loss 21841781
dgv10240n54 CNV loss 21841781

Additional Variant Information for MIR1229 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1229

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1229 Gene

Disorders for MIR1229 Gene

Additional Disease Information for MIR1229

No disorders were found for MIR1229 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1229 Gene

Publications for MIR1229 Gene

  1. Mammalian mirtron genes. (PMID: 17964270) Berezikov E … Lai EC (Molecular cell 2007) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
  3. MicroRNA-1229 overexpression promotes cell proliferation and tumorigenicity and activates Wnt/β-catenin signaling in breast cancer. (PMID: 26992223) Tan Z … Li J (Oncotarget 2016) 3

Products for MIR1229 Gene

Sources for MIR1229 Gene

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