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Aliases for MIR1228 Gene

Subcategory (RNA class) for MIR1228 Gene


Quality Score for this RNA gene is


Aliases for MIR1228 Gene

  • MicroRNA 1228 2 3 5
  • Hsa-Mir-1228 3
  • Mir-1228 3
  • MIRN1228 3

External Ids for MIR1228 Gene

Previous HGNC Symbols for MIR1228 Gene

  • MIRN1228

Previous GeneCards Identifiers for MIR1228 Gene

  • GC00U922937
  • GC12P055876
  • GC12P057588

Summaries for MIR1228 Gene

Entrez Gene Summary for MIR1228 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1228 Gene

MIR1228 (MicroRNA 1228) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1228 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1228 Gene

Genomics for MIR1228 Gene

GeneHancer (GH) Regulatory Elements for MIR1228 Gene

Promoters and enhancers for MIR1228 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12I057194 Enhancer 0.6 dbSUPER 550.8 +1.7 1693 2.5 CTCF KLF1 ZNF316 ZNF366 BRD9 GLIS1 ZNF341 ZFP36 CREM MAFK MIR1228 ENSG00000224713 NXPH4 LRP1
GH12I057228 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 12.2 +36.1 36063 3.4 HDGF CLOCK FOXA2 SMAD1 ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B SHMT2 ENSG00000276727 MIR1228 STAT6 ENSG00000224713 NDUFA4L2
GH12I057233 Enhancer 1.1 ENCODE dbSUPER 12.2 +40.4 40405 2.7 FOXA2 ZNF48 YY1 GLIS2 ZNF213 KLF7 PAF1 SP3 RXRA SP5 EEF1AKMT3 NEMP1 MIR1228 CDK4 OS9 ENSG00000276727 SHMT2 NDUFA4L2
GH12I057236 Enhancer 1 Ensembl ENCODE dbSUPER 12.2 +41.9 41925 0.3 RFX1 SP2 BMI1 SSRP1 POLR2A MBD1 ZBTB33 EZH2 MIR1228 NDUFA4L2 ENSG00000276727
GH12I057170 Enhancer 0.4 ENCODE dbSUPER 12.1 -22.9 -22863 1.5 LRP1 MIR1228 STAT6 NDUFA4L2 GLI1 INHBE GC12P057183 PIR32415 LRP1-AS
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1228 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1228 Gene

Genomic Locations for MIR1228 Gene
73 bases
Plus strand

Genomic View for MIR1228 Gene

Genes around MIR1228 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1228 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1228 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1228 Gene

Proteins for MIR1228 Gene

Post-translational modifications for MIR1228 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1228 Gene

Domains & Families for MIR1228 Gene

Gene Families for MIR1228 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1228: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1228 Gene

Function for MIR1228 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1228 Gene

Localization for MIR1228 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1228 Gene

Pathways & Interactions for MIR1228 Gene

SuperPathways for MIR1228 Gene

No Data Available

Interacting Proteins for MIR1228 Gene

Gene Ontology (GO) - Biological Process for MIR1228 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1228 Gene

Drugs & Compounds for MIR1228 Gene

No Compound Related Data Available

Transcripts for MIR1228 Gene

mRNA/cDNA for MIR1228 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1228 Gene

No ASD Table

Relevant External Links for MIR1228 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1228 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1228 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1228 Gene

Orthologs for MIR1228 Gene

Evolution for MIR1228 Gene

Gene Tree for MIR1228 (if available)
Gene Tree for MIR1228 (if available)

No data available for Orthologs for MIR1228 Gene

Paralogs for MIR1228 Gene

No data available for Paralogs for MIR1228 Gene

Variants for MIR1228 Gene

Sequence variations from dbSNP and Humsavar for MIR1228 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs1002902805 -- 57,193,263(+) C/T upstream_transcript_variant
rs1004754161 -- 57,194,280(+) T/C upstream_transcript_variant
rs1012008994 -- 57,194,930(+) C/T downstream_transcript_variant
rs1012353121 -- 57,194,825(+) A/G downstream_transcript_variant
rs1013338310 -- 57,193,179(+) T/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1228 Gene

Variant ID Type Subtype PubMed ID
dgv96n21 CNV loss 19592680
nsv482992 CNV gain+loss 15286789
nsv519293 CNV loss 19592680
nsv559023 CNV loss 21841781
nsv952189 CNV deletion 24416366

Additional Variant Information for MIR1228 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1228 Gene

Disorders for MIR1228 Gene

Additional Disease Information for MIR1228

No disorders were found for MIR1228 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1228 Gene

Publications for MIR1228 Gene

  1. microRNA-1228⁎ impairs the pro-angiogenic activity of gastric cancer cells by targeting macrophage migration inhibitory factor. (PMID: 28465246) Jia L … Zhang L (Life sciences 2017) 3 58
  2. MicroRNA-1228(*) inhibit apoptosis in A549 cells exposed to fine particulate matter. (PMID: 26867688) Li X … Chen R (Environmental science and pollution research international 2016) 3 58
  3. MiR-1228 promotes breast cancer cell growth and metastasis through targeting SCAI protein. (PMID: 26261546) Lin L … Liu M (International journal of clinical and experimental pathology 2015) 3 58
  4. miR-1228 promotes the proliferation and metastasis of hepatoma cells through a p53 forward feedback loop. (PMID: 25422913) Zhang Y … Tang H (British journal of cancer 2015) 3 58
  5. Human miR-1228 as a stable endogenous control for the quantification of circulating microRNAs in cancer patients. (PMID: 24488924) Hu J … Wang J (International journal of cancer 2014) 3 58

Products for MIR1228 Gene

Sources for MIR1228 Gene

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