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Aliases for MIR1206 Gene

Subcategory (RNA class) for MIR1206 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1206 Gene

  • MicroRNA 1206 2 3 5
  • Hsa-Mir-1206 3
  • MIRN1206 3

External Ids for MIR1206 Gene

Previous HGNC Symbols for MIR1206 Gene

  • MIRN1206

Previous GeneCards Identifiers for MIR1206 Gene

  • GC00U923053
  • GC08P129090
  • GC08P129021

Summaries for MIR1206 Gene

Entrez Gene Summary for MIR1206 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1206 Gene

MIR1206 (MicroRNA 1206) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1206 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1206 Gene

Genomics for MIR1206 Gene

GeneHancer (GH) Regulatory Elements for MIR1206 Gene

Promoters and enhancers for MIR1206 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08I128006 Enhancer 0.6 dbSUPER 550.8 -0.3 -253 4.8 L3MBTL2 CEBPB MNT CEBPG EP300 ZNF592 FOXA1 CREB1 KDM1A FOS ENSG00000278275 MIR1206 RNU4-25P MIR1207 TMEM75 CASC11 MYC RNU1-106P PVT1
GH08I128002 Enhancer 0.7 ENCODE dbSUPER 0.4 -7.6 -7648 0.2 NFIC POLR2A ZKSCAN8 EBF1 RUNX3 SPI1 RELA PVT1 RNU1-106P MIR1206
GH08I128001 Enhancer 0.5 ENCODE dbSUPER 0.4 -7.0 -7034 0.2 ZKSCAN8 MIR1205 MIR1207 TMEM75 PVT1 RNU1-106P MIR1206
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1206 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1206 Gene

Genomic Locations for MIR1206 Gene
chr8:128,008,898-128,008,956
(GRCh38/hg38)
Size:
59 bases
Orientation:
Plus strand
chr8:129,021,144-129,021,202
(GRCh37/hg19)

Genomic View for MIR1206 Gene

Genes around MIR1206 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1206 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1206 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1206 Gene

Proteins for MIR1206 Gene

Post-translational modifications for MIR1206 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1206 Gene

Domains & Families for MIR1206 Gene

Gene Families for MIR1206 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1206: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1206 Gene

Function for MIR1206 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1206 Gene

Localization for MIR1206 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1206 Gene

Pathways & Interactions for MIR1206 Gene

SuperPathways for MIR1206 Gene

No Data Available

Interacting Proteins for MIR1206 Gene

Gene Ontology (GO) - Biological Process for MIR1206 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1206 Gene

Drugs & Compounds for MIR1206 Gene

No Compound Related Data Available

Transcripts for MIR1206 Gene

mRNA/cDNA for MIR1206 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1206 Gene

No ASD Table

Relevant External Links for MIR1206 Gene

GeneLoc Exon Structure for
MIR1206
ECgene alternative splicing isoforms for
MIR1206

Expression for MIR1206 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1206 Gene:

MIR1206
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1206 Gene

Orthologs for MIR1206 Gene

Evolution for MIR1206 Gene

ENSEMBL:
Gene Tree for MIR1206 (if available)
TreeFam:
Gene Tree for MIR1206 (if available)

No data available for Orthologs for MIR1206 Gene

Paralogs for MIR1206 Gene

No data available for Paralogs for MIR1206 Gene

Variants for MIR1206 Gene

Sequence variations from dbSNP and Humsavar for MIR1206 Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1001876732 -- 128,008,510(+) T/C upstream_transcript_variant
rs1001927143 -- 128,008,249(+) TTT/TT upstream_transcript_variant
rs1003148453 -- 128,007,848(+) C/T upstream_transcript_variant
rs1003526859 -- 128,008,222(+) G/T upstream_transcript_variant
rs1004196908 -- 128,007,582(+) A/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1206 Gene

Variant ID Type Subtype PubMed ID
nsv499795 OTHER inversion 21111241
nsv7419 OTHER inversion 18451855

Additional Variant Information for MIR1206 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1206

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1206 Gene

Disorders for MIR1206 Gene

Additional Disease Information for MIR1206

No disorders were found for MIR1206 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1206 Gene

Publications for MIR1206 Gene

  1. Common genetic variants in miR-1206 (8q24.2) and miR-612 (11q13.3) affect biogenesis of mature miRNA forms. (PMID: 23077621) Kim HK … Chanock SJ (PloS one 2012) 3 58
  2. The identification of microRNAs in a genomically unstable region of human chromosome 8q24. (PMID: 18314482) Huppi K … Caplen NJ (Molecular cancer research : MCR 2008) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR1206 Gene

Sources for MIR1206 Gene

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