microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1199 Gene

Subcategory (RNA class) for MIR1199 Gene

miRNA

Number of RNA Genes sources:

1 / 14

Aliases for MIR1199 Gene

  • MicroRNA 1199 2 3 5
  • MicroRNA Mir-1199 3
  • Hsa-Mir-1199 3
  • MIMAT0031120 51
  • MIMAT0031119 51
  • MI0020340 51
  • MIR1199 2

External Ids for MIR1199 Gene

Additional External Ids for MIR1199 Gene

Previous GeneCards Identifiers for MIR1199 Gene

  • GC19P014188

Summaries for MIR1199 Gene

Entrez Gene Summary for MIR1199 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1199 Gene

MIR1199 (MicroRNA 1199) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1199 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1199 Gene

Genomics for MIR1199 Gene

GeneHancer (GH) Regulatory Elements for MIR1199 Gene

Promoters and enhancers for MIR1199 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J014071 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 500.7 +0.3 306 4.3 ZNF217 CTCF SIN3A NRF1 POLR2G TEAD4 ZFX ZNF10 POLR2A ZBTB10 MISP3 MIR1199 CCDC130 RFX1 TRMT1 DCAF15 DDX39A PALM3 ZNF333 PRKACA
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR1199 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1199 Gene

Genomic Locations for MIR1199 Gene
chr19:14,073,361-14,073,479
(GRCh38/hg38)
Size:
119 bases
Orientation:
Plus strand
chr19:14,183,348-14,185,874
(GRCh37/hg19)
Size:
2,527 bases
Orientation:
Plus strand

Genomic View for MIR1199 Gene

Genes around MIR1199 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1199 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1199 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1199 Gene

Proteins for MIR1199 Gene

Post-translational modifications for MIR1199 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1199 Gene

Domains & Families for MIR1199 Gene

Gene Families for MIR1199 Gene

HGNC:
genes like me logo Genes that share domains with MIR1199: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1199 Gene

Function for MIR1199 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1199 Gene

Localization for MIR1199 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR1199 gene
Compartment Confidence
nucleus 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1199 Gene

Pathways & Interactions for MIR1199 Gene

PathCards logo

SuperPathways for MIR1199 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR1199 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR1199 Gene

Drugs & Compounds for MIR1199 Gene

No Compound Related Data Available

Transcripts for MIR1199 Gene

mRNA/cDNA for MIR1199 Gene

3 RNACentral transcripts :
1 REFSEQ mRNAs :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
3 miRBase transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1199 Gene

No ASD Table

Relevant External Links for MIR1199 Gene

GeneLoc Exon Structure for
MIR1199

Expression for MIR1199 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1199 Gene

genes like me logo Genes that share expression patterns with MIR1199: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1199 Gene

Orthologs for MIR1199 Gene

Evolution for MIR1199 Gene

ENSEMBL:
Gene Tree for MIR1199 (if available)
TreeFam:
Gene Tree for MIR1199 (if available)

No data available for Orthologs for MIR1199 Gene

Paralogs for MIR1199 Gene

No data available for Paralogs for MIR1199 Gene

Variants for MIR1199 Gene

Additional dbSNP identifiers (rs#s) for MIR1199 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1199 Gene

Variant ID Type Subtype PubMed ID
dgv49n68 CNV loss 17160897
nsv578642 CNV gain 21841781
nsv828452 CNV loss 20364138
nsv828454 CNV gain 20364138
nsv833761 CNV loss 17160897

Variation tolerance for MIR1199 Gene

Gene Damage Index Score: 14.96; 96.81% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MIR1199 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1199

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MIR1199 Gene

Disorders for MIR1199 Gene

Additional Disease Information for MIR1199

No disorders were found for MIR1199 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1199 Gene

Publications for MIR1199 Gene

  1. Human hepatocellular carcinoma cell-specific miRNAs reveal the differential expression of miR-24 and miR-27a in cirrhotic/non-cirrhotic HCC. (PMID: 23229173) Salvi A … De Petro G (International journal of oncology 2013) 3 54
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR1199 Gene

Sources for MIR1199 Gene