microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1197 Gene

Subcategory (RNA class) for MIR1197 Gene

miRNA

Number of RNA Genes sources:

4 / 17

Aliases for MIR1197 Gene

  • MicroRNA 1197 2 3 5
  • Hsa-Mir-1197 2 3
  • MIR1197 2 5
  • Hsa-Mir-154-P30 178
  • MIMAT0005955 50
  • MI0006656 50
  • MIRN1197 3
  • Mir-1197 3
  • RF00641 168

External Ids for MIR1197 Gene

Previous HGNC Symbols for MIR1197 Gene

  • MIRN1197

Previous GeneCards Identifiers for MIR1197 Gene

  • GC00U922895
  • GC14P100936
  • GC14P101492
  • GC14P101806
  • GC14P101946
  • GC14P102137
  • GC14P101084
  • GC14P101354
  • GC14P103518
  • GC14P103741
  • GC14P103941
  • GC14P104303
  • GC14P102032
  • GC14P102279
  • GC14P102451
  • GC14P102626
  • GC14P102795
  • GC14P102972
  • GC14P103156
  • GC14P103355

Summaries for MIR1197 Gene

Entrez Gene Summary for MIR1197 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1197 Gene

MIR1197 (MicroRNA 1197) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR1197 include Intracranial Berry Aneurysm.

Rfam classification for MIR1197 Gene

Additional gene information for MIR1197 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR1197 Gene

Genomics for MIR1197 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR1197 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14J101091 Enhancer 0.3 Ensembl 10.2 +65.7 65737 1 JUN MIR377 MIR154 MIR496 MIR134 MIR323B MIR485 MIR487A MIR329-1 MIR329-2 MIR323A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR1197 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR1197 Gene

Genomic Locations for MIR1197 Gene
chr14:101,025,564-101,025,651
(GRCh38/hg38)
Size:
88 bases
Orientation:
Plus strand
chr14:101,491,901-101,491,988
(GRCh37/hg19)
Size:
88 bases
Orientation:
Plus strand

Genomic View for MIR1197 Gene

Genes around MIR1197 on UCSC Golden Path with GeneCards custom track
MIR1197 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR1197 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1197 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1197 Gene

Proteins for MIR1197 Gene

Post-translational modifications for MIR1197 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1197 Gene

Domains & Families for MIR1197 Gene

Gene Families for MIR1197 Gene

genes like me logo Genes that share domains with MIR1197: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1197 Gene

Function for MIR1197 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1197 Gene

Localization for MIR1197 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1197 Gene

Pathways & Interactions for MIR1197 Gene

PathCards logo

SuperPathways for MIR1197 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR1197 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IEA --
genes like me logo Genes that share ontologies with MIR1197: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR1197 Gene

Drugs & Compounds for MIR1197 Gene

No Compound Related Data Available

Transcripts for MIR1197 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR1197 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075B597_9606 precursor_RNA 88 5

HGNC: 35376,

RefSeq: NR_031713,

Ensembl: ENST00000408818 (view in UCSC) ,

miRBase: MI0006656,

ENA: LM610187.1:1..88:precursor_RNA,

URS00003E5E03_9606 miRNA 21 4

RefSeq: NR_031713,

miRBase: MIMAT0005955,

MirGeneDB: Hsa-Mir-154-P30_3p,

ENA: LM380727.1:1..21:ncRNA, LM610187.1:57..77:ncRNA,

URS00006981EA_9606 precursor_RNA 80 1

Rfam: RF00641,

URS0000EFD31A_9606 precursor_RNA 57 1

MirGeneDB: Hsa-Mir-154-P30,

URS000075B10C_9606 miRNA 21 1

MirGeneDB: Hsa-Mir-154-P30_5p,

MIR1197 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR1197 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1197 Gene

No ASD Table

Relevant External Links for MIR1197 Gene

GeneLoc Exon Structure for
MIR1197

Expression for MIR1197 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1197 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR1197

genes like me logo Genes that share expression patterns with MIR1197: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1197 Gene

Orthologs for MIR1197 Gene

Evolution for MIR1197 Gene

ENSEMBL:
Gene Tree for MIR1197 (if available)
TreeFam:
Gene Tree for MIR1197 (if available)

No data available for Orthologs for MIR1197 Gene

Paralogs for MIR1197 Gene

No data available for Paralogs for MIR1197 Gene

Variants for MIR1197 Gene

Additional dbSNP identifiers (rs#s) for MIR1197 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1197 Gene

Variant ID Type Subtype PubMed ID
esv3635521 CNV gain 21293372
esv3635523 CNV gain 21293372
nsv1040993 CNV gain 25217958
nsv1426 CNV insertion 18451855
nsv565859 CNV gain 21841781
nsv565860 CNV gain 21841781

Additional Variant Information for MIR1197 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1197

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR1197 Gene

Disorders for MIR1197 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR1197 Gene - From: DISEASES

Disorder Aliases PubMed IDs
intracranial berry aneurysm
  • aneurysm, intracranial berry, 1
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR1197

genes like me logo Genes that share disorders with MIR1197: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR1197 Gene

Publications for MIR1197 Gene

  1. MicroRNA-1197 downregulation inhibits proliferation and migration in human non- small cell lung cancer cells by upregulating HOXC11. (PMID: 31181445) Sun B … Zhou H (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019) 3
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  3. New miRNAs cloned from neuroblastoma. (PMID: 18230126) Afanasyeva EA … Westermann F (BMC genomics 2008) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR1197 Gene

Sources for MIR1197 Gene