microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1193 Gene

Subcategory (RNA class) for MIR1193 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR1193 Gene

  • MicroRNA 1193 2 3 5
  • Hsa-Mir-1193 2 3
  • MIR1193 2 5
  • Hsa-Mir-154-P29 178
  • MIMAT0015049 50
  • MI0014205 50

External Ids for MIR1193 Gene

Previous GeneCards Identifiers for MIR1193 Gene

  • GC14U901174
  • GC14P081679
  • GC14P101669
  • GC14P101704
  • GC14P101745
  • GC14P101784
  • GC14P101845
  • GC14P101986
  • GC14P102184
  • GC14P101244
  • GC14P101851
  • GC14P103600
  • GC14P103817
  • GC14P104074
  • GC14P104436
  • GC14P102104
  • GC14P102338
  • GC14P102511
  • GC14P102690
  • GC14P102858
  • GC14P103034
  • GC14P103228
  • GC14P103416

Summaries for MIR1193 Gene

Entrez Gene Summary for MIR1193 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1193 Gene

MIR1193 (MicroRNA 1193) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR1193 include Orthostatic Intolerance.

Additional gene information for MIR1193 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1193 Gene

Genomics for MIR1193 Gene

Genomic Locations for MIR1193 Gene

Genomic Locations for MIR1193 Gene
chr14:101,030,052-101,030,129
(GRCh38/hg38)
Size:
78 bases
Orientation:
Plus strand
chr14:101,496,389-101,496,466
(GRCh37/hg19)
Size:
78 bases
Orientation:
Plus strand

Genomic View for MIR1193 Gene

Genes around MIR1193 on UCSC Golden Path with GeneCards custom track
MIR1193 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR1193 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1193 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1193 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR1193 Gene

Proteins for MIR1193 Gene

Post-translational modifications for MIR1193 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1193 Gene

Domains & Families for MIR1193 Gene

Gene Families for MIR1193 Gene

HGNC:
genes like me logo Genes that share domains with MIR1193: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1193 Gene

Function for MIR1193 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1193 Gene

Localization for MIR1193 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1193 Gene

Pathways & Interactions for MIR1193 Gene

PathCards logo

SuperPathways for MIR1193 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR1193 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR1193 Gene

Drugs & Compounds for MIR1193 Gene

No Compound Related Data Available

Transcripts for MIR1193 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR1193 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075C2A9_9606 precursor_RNA 78 4

HGNC: 38247,

RefSeq: NR_036132,

Ensembl: ENST00000408109 (view in UCSC) ,

miRBase: MI0014205,

URS000002F2FA_9606 miRNA 23 2

RefSeq: NR_036132,

miRBase: MIMAT0015049,

URS0000EFE3EA_9606 precursor_RNA 58 1

MirGeneDB: Hsa-Mir-154-P29,

URS000075C9E0_9606 miRNA 22 1

MirGeneDB: Hsa-Mir-154-P29_3p,

URS00007E4896_9606 miRNA 21 1

MirGeneDB: Hsa-Mir-154-P29_5p,

MIR1193 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1193 Gene

No ASD Table

Relevant External Links for MIR1193 Gene

GeneLoc Exon Structure for
MIR1193

No data available for mRNA/cDNA for MIR1193 Gene

Expression for MIR1193 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1193 Gene

Orthologs for MIR1193 Gene

Evolution for MIR1193 Gene

ENSEMBL:
Gene Tree for MIR1193 (if available)
TreeFam:
Gene Tree for MIR1193 (if available)

No data available for Orthologs for MIR1193 Gene

Paralogs for MIR1193 Gene

No data available for Paralogs for MIR1193 Gene

Variants for MIR1193 Gene

Additional dbSNP identifiers (rs#s) for MIR1193 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1193 Gene

Variant ID Type Subtype PubMed ID
esv3635521 CNV gain 21293372
esv3635523 CNV gain 21293372
nsv1040993 CNV gain 25217958
nsv1426 CNV insertion 18451855
nsv565859 CNV gain 21841781
nsv565860 CNV gain 21841781

Additional Variant Information for MIR1193 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1193

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR1193 Gene

Disorders for MIR1193 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR1193 Gene - From: DISEASES

Disorder Aliases PubMed IDs
orthostatic intolerance
  • floppy mitral valve
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR1193

genes like me logo Genes that share disorders with MIR1193: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR1193 Gene

Publications for MIR1193 Gene

  1. A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220. (PMID: 28625976) Hou P … Huang J (Cancer research 2017) 3
  2. miR-1193 Suppresses Proliferation and Invasion of Human Breast Cancer Cells Through Directly Targeting IGF2BP2. (PMID: 27733218) Li X … Lu H (Oncology research 2017) 3
  3. The screening of the functional microRNA binding site SNPs in sporadic colorectal cancer genes. (PMID: 28494187) He H … Yang J (Cancer biology & therapy 2017) 3
  4. miR-1193 Suppresses the Proliferation and Invasion of Human T-Cell Leukemia Cells Through Directly Targeting the Transmembrane 9 Superfamily 3 (TM9SF3). (PMID: 28390114) Shen L … Mei S (Oncology research 2017) 3
  5. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3

Products for MIR1193 Gene

Sources for MIR1193 Gene