microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1178 Gene

Subcategory (RNA class) for MIR1178 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR1178 Gene

  • MicroRNA 1178 2 3 5
  • Hsa-Mir-1178 2 3
  • MIR1178 2 5
  • MIMAT0022940 50
  • MIMAT0005823 50
  • MI0006271 50
  • MIRN1178 3
  • RF02014 168

External Ids for MIR1178 Gene

Previous HGNC Symbols for MIR1178 Gene

  • MIRN1178

Previous GeneCards Identifiers for MIR1178 Gene

  • GC00U922977
  • GC12M118636
  • GC12M120151

Summaries for MIR1178 Gene

Entrez Gene Summary for MIR1178 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1178 Gene

MIR1178 (MicroRNA 1178) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Signaling by GPCR and G13 Signaling Pathway.

Rfam classification for MIR1178 Gene

Additional gene information for MIR1178 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR1178 Gene

Genomics for MIR1178 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR1178 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J119678 Enhancer 1.3 Ensembl ENCODE CraniofacialAtlas dbSUPER 12.3 +30.3 30304 9.7 GATAD2A REST ZNF629 RELA ZIC2 RXRB SP1 EED SOX13 TCF7 PRKAB1 MIR1178 CIT ENSG00000248636 TMEM233 HSALNG0094474 lnc-RAB35-6
GH12J119715 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 0.7 -2.9 -2867 2.4 GATAD2A REST RCOR2 TARDBP JUND FOXA1 RXRB NR2C1 SP1 GABPA HSALNG0094477 CIT TMEM233 PRKAB1 MIR1178
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR1178 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR1178 Gene

Genomic Locations for MIR1178 Gene
chr12:119,713,624-119,713,734
(GRCh38/hg38)
Size:
111 bases
Orientation:
Minus strand
chr12:120,151,439-120,151,529
(GRCh37/hg19)
Size:
91 bases
Orientation:
Minus strand

Genomic View for MIR1178 Gene

Genes around MIR1178 on UCSC Golden Path with GeneCards custom track
MIR1178 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR1178 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1178 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1178 Gene

Proteins for MIR1178 Gene

Post-translational modifications for MIR1178 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1178 Gene

Domains & Families for MIR1178 Gene

Gene Families for MIR1178 Gene

HGNC:
genes like me logo Genes that share domains with MIR1178: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1178 Gene

Function for MIR1178 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1178 Gene

Localization for MIR1178 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1178 Gene

Pathways & Interactions for MIR1178 Gene

genes like me logo Genes that share pathways with MIR1178: view

Pathways by source for MIR1178 Gene

1 BioSystems pathway for MIR1178 Gene

Gene Ontology (GO) - Biological Process for MIR1178 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IEA --
genes like me logo Genes that share ontologies with MIR1178: view

No data available for Interacting Proteins and SIGNOR curated interactions for MIR1178 Gene

Drugs & Compounds for MIR1178 Gene

No Compound Related Data Available

Transcripts for MIR1178 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR1178 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075AF6E_9606 precursor_RNA 91 4

HGNC: 35259,

RefSeq: NR_031589,

Ensembl: ENST00000408396 (view in UCSC) ,

miRBase: MI0006271,

URS000075AB23_9606 miRNA 21 2

RefSeq: NR_031589,

miRBase: MIMAT0005823,

URS00008E3963_9606 miRNA 18 2

RefSeq: NR_031589,

miRBase: MIMAT0022940,

URS00006BD53C_9606 precursor_RNA 111 1

Rfam: RF02014,

MIR1178 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1178 Gene

No ASD Table

Relevant External Links for MIR1178 Gene

GeneLoc Exon Structure for
MIR1178

No data available for mRNA/cDNA for MIR1178 Gene

Expression for MIR1178 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1178 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR1178

genes like me logo Genes that share expression patterns with MIR1178: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1178 Gene

Orthologs for MIR1178 Gene

Evolution for MIR1178 Gene

ENSEMBL:
Gene Tree for MIR1178 (if available)
TreeFam:
Gene Tree for MIR1178 (if available)

No data available for Orthologs for MIR1178 Gene

Paralogs for MIR1178 Gene

No data available for Paralogs for MIR1178 Gene

Variants for MIR1178 Gene

Additional dbSNP identifiers (rs#s) for MIR1178 Gene

Additional Variant Information for MIR1178 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1178

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR1178 Gene

Disorders for MIR1178 Gene

Additional Disease Information for MIR1178

No disorders were found for MIR1178 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1178 Gene

Publications for MIR1178 Gene

  1. MiR-1178-3p promotes the proliferation, migration and invasion of nasopharyngeal carcinoma Sune-1 cells by targeting STK4. (PMID: 30972994) Wang LQ … Zhang Y (Journal of biological regulators and homeostatic agents 2019) 3
  2. Circular RNA circ-ZKSCAN1 inhibits bladder cancer progression through miR-1178-3p/p21 axis and acts as a prognostic factor of recurrence. (PMID: 31481066) Bi J … Lin T (Molecular cancer 2019) 3
  3. MiR-1178 regulates mycobacterial survival and inflammatory responses in Mycobacterium tuberculosis-infected macrophages partly via TLR4. (PMID: 29781535) Shi G … Wang W (Journal of cellular biochemistry 2018) 3
  4. MiR-1178 promotes the proliferation, G1/S transition, migration and invasion of pancreatic cancer cells by targeting CHIP. (PMID: 25635996) Cao Z … Zhao Y (PloS one 2015) 3
  5. MicroRNA expression signature of human sarcomas. (PMID: 17922033) Subramanian S … van de Rijn M (Oncogene 2008) 3

Products for MIR1178 Gene

Sources for MIR1178 Gene