microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR10526 Gene

Data sources for MIR10526 Gene:

RNA type for MIR10526 Gene

miRNA

Aliases for MIR10526 Gene

External Ids for MIR10526 Gene

Previous GeneCards Identifiers for MIR10526 Gene

  • GC11U903135

Summaries for MIR10526 Gene

Entrez Gene Summary for MIR10526 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR10526 Gene

MIR10526 (MicroRNA 10526) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR10526 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR10526 Gene

Genomics for MIR10526 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR10526 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J122150 Enhancer 0.9 Ensembl ENCODE dbSUPER 250.7 +0.7 696 2.5 FOXA2 TEAD3 HMG20A HMG20B ZNF792 HNF4A ARID3A HLF TCF7 RERE MIR100 MIR10526 RF00104-008 BLID MIR100HG MIRLET7A2 ENSG00000255219 UBASH3B
GH11J122145 Enhancer 0.8 Ensembl ENCODE dbSUPER 0.7 +5.0 4968 5.6 ATF2 EP300 JUND USF2 ATF7 USF1 MIRLET7A2 BLID MIR100HG MIR10526 ENSG00000255219 UBASH3B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR10526 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR10526 Gene

Latest Assembly
chr11:122,152,093-122,152,169
(GRCh38/hg38)
Size:
77 bases
Orientation:
Minus strand

Previous Assembly
chr11:122,022,811-122,022,864
(GRCh37/hg19 by Entrez Gene)
Size:
54 bases
Orientation:
Minus strand

Genomic View for MIR10526 Gene

Genes around MIR10526 on UCSC Golden Path with GeneCards custom track
MIR10526 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR10526 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR10526 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR10526 Gene

Proteins for MIR10526 Gene

Post-translational modifications for MIR10526 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR10526 Gene

Domains & Families for MIR10526 Gene

Gene Families for MIR10526 Gene

HGNC:
genes like me logo Genes that share domains with MIR10526: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR10526 Gene

Function for MIR10526 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR10526 Gene

Localization for MIR10526 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR10526 Gene

Pathways & Interactions for MIR10526 Gene

PathCards logo

SuperPathways for MIR10526 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR10526 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR10526 Gene

Drugs & Compounds for MIR10526 Gene

No Compound Related Data Available

Transcripts for MIR10526 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR10526 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS0000D56630_9606 pre_miRNA 54 2

RefSeq: NR_162117,

miRBase: MI0033673,

URS0000D52683_9606 miRNA 20 2

RefSeq: NR_162117,

miRBase: MIMAT0041996,

URS000043B1B1_9606 precursor_RNA 77 1

ENA: JX952208.1:1..77:precursor_RNA,

MIR10526 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR10526 Gene

No ASD Table

Relevant External Links for MIR10526 Gene

GeneLoc Exon Structure for
MIR10526

No data available for mRNA/cDNA for MIR10526 Gene

Expression for MIR10526 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR10526 Gene

Orthologs for MIR10526 Gene

No data available for Orthologs and Evolution for MIR10526 Gene

Paralogs for MIR10526 Gene

No data available for Paralogs for MIR10526 Gene

Variants for MIR10526 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR10526 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Additional Variant Information for MIR10526 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR10526
Leiden Open Variation Database (LOVD)
MIR10526

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR10526 Gene

Disorders for MIR10526 Gene

No disorders were found for MIR10526 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for MIR10526 Gene

Publications for MIR10526 Gene

  1. Selective microRNA-Offset RNA expression in human embryonic stem cells. (PMID: 25822230) Asikainen S … Hovatta O (PloS one 2015) 2 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR10526 Gene

Sources for MIR10526 Gene