microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR103B1 Gene

Subcategory (RNA class) for MIR103B1 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR103B1 Gene

  • MicroRNA 103b-1 2 3 5
  • MicroRNA 103-1-As 2 3
  • Hsa-Mir-103-1-As 2 3
  • Hsa-Mir-103b-1 2 3
  • MIR103B1 2 5
  • MIMAT0007402 50
  • MIRN103-1AS 3
  • MIR103-1AS 3
  • MI0007261 50

External Ids for MIR103B1 Gene

Previous HGNC Symbols for MIR103B1 Gene

  • MIRN103-1AS
  • MIR103-1AS

Previous GeneCards Identifiers for MIR103B1 Gene

  • GC05P167988

Summaries for MIR103B1 Gene

Entrez Gene Summary for MIR103B1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR103B1 Gene

MIR103B1 (MicroRNA 103b-1) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

Rfam classification for MIR103B1 Gene

  • mir-103/107 microRNA precursor

Additional gene information for MIR103B1 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR103B1 Gene

Genomics for MIR103B1 Gene

Genomic Locations for MIR103B1 Gene

Genomic Locations for MIR103B1 Gene
chr5:168,560,904-168,560,965
(GRCh38/hg38)
Size:
62 bases
Orientation:
Plus strand
chr5:167,987,909-167,987,970
(GRCh37/hg19)
Size:
62 bases
Orientation:
Plus strand

Genomic View for MIR103B1 Gene

Genes around MIR103B1 on UCSC Golden Path with GeneCards custom track
MIR103B1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR103B1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR103B1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR103B1 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR103B1 Gene

Proteins for MIR103B1 Gene

Post-translational modifications for MIR103B1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR103B1 Gene

Domains & Families for MIR103B1 Gene

Gene Families for MIR103B1 Gene

genes like me logo Genes that share domains with MIR103B1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR103B1 Gene

Function for MIR103B1 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR103B1 Gene

Localization for MIR103B1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR103B1 Gene

Pathways & Interactions for MIR103B1 Gene

PathCards logo

SuperPathways for MIR103B1 Gene

SuperPathway Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR103B1: view

Pathways by source for MIR103B1 Gene

1 KEGG pathway for MIR103B1 Gene

Gene Ontology (GO) - Biological Process for MIR103B1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IEA --
genes like me logo Genes that share ontologies with MIR103B1: view

No data available for Interacting Proteins and SIGNOR curated interactions for MIR103B1 Gene

Drugs & Compounds for MIR103B1 Gene

No Compound Related Data Available

Transcripts for MIR103B1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR103B1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075ED36_9606 precursor_RNA 62 4

HGNC: 35384,

RefSeq: NR_031721,

Ensembl: ENST00000636572 (view in UCSC) ,

miRBase: MI0007261,

URS000075C8F4_9606 miRNA 23 2

RefSeq: NR_031721, NR_031722,

miRBase: MIMAT0007402,

MIR103B1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR103B1 Gene

No ASD Table

Relevant External Links for MIR103B1 Gene

GeneLoc Exon Structure for
MIR103B1

No data available for mRNA/cDNA for MIR103B1 Gene

Expression for MIR103B1 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR103B1 Gene

Orthologs for MIR103B1 Gene

Evolution for MIR103B1 Gene

ENSEMBL:
Gene Tree for MIR103B1 (if available)
TreeFam:
Gene Tree for MIR103B1 (if available)

No data available for Orthologs for MIR103B1 Gene

Paralogs for MIR103B1 Gene

No data available for Paralogs for MIR103B1 Gene

Variants for MIR103B1 Gene

Additional dbSNP identifiers (rs#s) for MIR103B1 Gene

Additional Variant Information for MIR103B1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR103B1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR103B1 Gene

Disorders for MIR103B1 Gene

Additional Disease Information for MIR103B1

No disorders were found for MIR103B1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR103B1 Gene

Publications for MIR103B1 Gene

  1. Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing. (PMID: 18524951) Azuma-Mukai A … Siomi MC (Proceedings of the National Academy of Sciences of the United States of America 2008) 2 3
  2. miR-103 promotes the metastasis and EMT of hepatocellular carcinoma by directly inhibiting LATS2. (PMID: 30272278) Han LL … Zhang SQ (International journal of oncology 2018) 3
  3. Upregulation of serum miR-103 predicts unfavorable prognosis in patients with colorectal cancer. (PMID: 30058684) Wang DS … Gao Y (European review for medical and pharmacological sciences 2018) 3
  4. miRNA-103: molecular link between insulin resistance and nonalcoholic fatty liver disease. (PMID: 25593466) Xu Q … Yao MX (World journal of gastroenterology 2015) 3
  5. MicroRNA-103 promotes colorectal cancer by targeting tumor suppressor DICER and PTEN. (PMID: 24828205) Geng L … Fang XD (International journal of molecular sciences 2014) 3

Products for MIR103B1 Gene

Sources for MIR103B1 Gene