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Aliases for MIR103A2 Gene

Subcategory (RNA class) for MIR103A2 Gene


Quality Score for this RNA gene is


Aliases for MIR103A2 Gene

  • MicroRNA 103a-2 2 3 5
  • MicroRNA 103-2 2 3
  • Hsa-Mir-103a-2 3
  • Hsa-Mir-103-2 3
  • Mir-103a-2 3
  • MIRN103-2 3
  • MIR103-2 3

External Ids for MIR103A2 Gene

ORGUL Members for MIR103A2 Gene

Previous HGNC Symbols for MIR103A2 Gene

  • MIRN103-2
  • MIR103-2

Previous GeneCards Identifiers for MIR103A2 Gene

  • GC20P003899
  • GC20P003902
  • GC20P003906

Summaries for MIR103A2 Gene

Entrez Gene Summary for MIR103A2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR103A2 Gene

MIR103A2 (MicroRNA 103a-2) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer and MicroRNAs in cardiomyocyte hypertrophy.

Additional gene information for MIR103A2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR103A2 Gene

Genomics for MIR103A2 Gene

GeneHancer (GH) Regulatory Elements for MIR103A2 Gene

Promoters and enhancers for MIR103A2 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH20I003871 Enhancer 0.4 ENCODE 11.6 -45.7 -45654 0.9 ZNF664 RFX1 BMI1 PIR51563 MIR103A2 CENPB CDC25B AP5S1 SPEF1 RNF24 MAVS
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR103A2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR103A2 Gene

Genomic Locations for MIR103A2 Gene
78 bases
Plus strand

Genomic View for MIR103A2 Gene

Genes around MIR103A2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR103A2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR103A2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR103A2 Gene

Proteins for MIR103A2 Gene

Post-translational modifications for MIR103A2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR103A2 Gene

Domains & Families for MIR103A2 Gene

Gene Families for MIR103A2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR103A2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR103A2 Gene

Function for MIR103A2 Gene

Gene Ontology (GO) - Molecular Function for MIR103A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 15131085
genes like me logo Genes that share ontologies with MIR103A2: view

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR103A2 Gene

Localization for MIR103A2 Gene

Gene Ontology (GO) - Cellular Components for MIR103A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR103A2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR103A2 Gene

Pathways & Interactions for MIR103A2 Gene

genes like me logo Genes that share pathways with MIR103A2: view

Pathways by source for MIR103A2 Gene

1 BioSystems pathway for MIR103A2 Gene
1 KEGG pathway for MIR103A2 Gene

Interacting Proteins for MIR103A2 Gene

Gene Ontology (GO) - Biological Process for MIR103A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IDA 15131085
genes like me logo Genes that share ontologies with MIR103A2: view

No data available for SIGNOR curated interactions for MIR103A2 Gene

Drugs & Compounds for MIR103A2 Gene

No Compound Related Data Available

Transcripts for MIR103A2 Gene

mRNA/cDNA for MIR103A2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR103A2 Gene

No ASD Table

Relevant External Links for MIR103A2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR103A2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR103A2 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR103A2 Gene:

genes like me logo Genes that share expression patterns with MIR103A2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR103A2 Gene

Orthologs for MIR103A2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR103A2 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia cfa-mir-103-2 34
  • 100 (a)
(Pan troglodytes)
Mammalia ptr-mir-103-2 34
  • 100 (a)
(Bos Taurus)
Mammalia bta-mir-103-2 34
  • 95 (a)
(Mus musculus)
Mammalia Mir103-2 34
  • 90 (a)
(Monodelphis domestica)
Mammalia mdo-mir-103-2 34
  • 88 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-103-2 34
  • 71 (a)
(Gallus gallus)
Aves gga-mir-103-2 34
  • 87 (a)
(Danio rerio)
Actinopterygii CT573279.1 34
  • 72 (a)
Species where no ortholog for MIR103A2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR103A2 Gene

Gene Tree for MIR103A2 (if available)
Gene Tree for MIR103A2 (if available)

Paralogs for MIR103A2 Gene

No data available for Paralogs for MIR103A2 Gene

Variants for MIR103A2 Gene

Sequence variations from dbSNP and Humsavar for MIR103A2 Gene

SNP ID Clin Chr 20 pos Variation AA Info Type
rs10679953 benign, not specified, Pigmentary pallidal degeneration 3,916,913(+) TTCCCC/TTCCCCTTCCCC upstream_transcript_variant
rs137852968 pathogenic, Hypoprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration 3,916,955(+) C/A/T upstream_transcript_variant
rs148987163 pathogenic, Hypoprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration, Pigmentary pallidal degeneration 3,916,926(+) G/T upstream_transcript_variant
rs766251466 pathogenic, Pigmentary pallidal degeneration 3,916,956(+) GAG/ upstream_transcript_variant
rs1000691962 -- 3,915,593(+) C/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR103A2 Gene

Variant ID Type Subtype PubMed ID
esv3645053 CNV loss 21293372
esv3645054 CNV gain 21293372
nsv828673 CNV gain 20364138

Additional Variant Information for MIR103A2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR103A2 Gene

Disorders for MIR103A2 Gene

Additional Disease Information for MIR103A2

No disorders were found for MIR103A2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR103A2 Gene

Publications for MIR103A2 Gene

  1. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
  2. Novel MicroRNA Regulators of Atrial Natriuretic Peptide Production. (PMID: 27185878) Wu C … Newton-Cheh C (Molecular and cellular biology 2016) 3 58
  3. miRNA-103: molecular link between insulin resistance and nonalcoholic fatty liver disease. (PMID: 25593466) Xu Q … Yao MX (World journal of gastroenterology 2015) 3 58
  4. Overexpression of blood microRNAs 103a, 30b, and 29a in L-dopa-treated patients with PD. (PMID: 25596505) Serafin A … Schwienbacher C (Neurology 2015) 3 58
  5. Investigation of Gene Regulatory Networks Associated with Autism Spectrum Disorder Based on MiRNA Expression in China. (PMID: 26061495) Huang F … Jiang H (PloS one 2015) 3 58

Products for MIR103A2 Gene

Sources for MIR103A2 Gene

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