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Aliases for MIR100HG Gene

Subcategory (RNA class) for MIR100HG Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR100HG Gene

  • Mir-100-Let-7a-2-Mir-125b-1 Cluster Host Gene 2 3 5
  • Mir-100-Let-7a-2 Cluster Host Gene (Non-Protein Coding) 2 3
  • Neuronal Differentiation LncRNA Hosting MiR-125 2 3
  • Adipogenesis Down-Regulated Transcript 1 2 3
  • LncRNA Neuronal 2 2 3
  • Mir-100-Let-7a-2 Cluster Host Gene 2
  • Linc-NeD125 3
  • LncRNA-N2 3
  • AGD1 3

External Ids for MIR100HG Gene

Previous GeneCards Identifiers for MIR100HG Gene

  • GC11M121961
  • GC11M121902
  • GC11M122089

Summaries for MIR100HG Gene

Entrez Gene Summary for MIR100HG Gene

  • This gene produces long non-coding RNAs that act as regulators of cell proliferation. Alternative promoter usage and splicing results in multiple transcript variants. Some transcript variants may promote growth, while others may act to negatively regulate cell division. [provided by RefSeq, May 2016]

GeneCards Summary for MIR100HG Gene

MIR100HG (Mir-100-Let-7a-2-Mir-125b-1 Cluster Host Gene) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR100HG Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR100HG Gene

Genomics for MIR100HG Gene

GeneHancer (GH) Regulatory Elements for MIR100HG Gene

Promoters and enhancers for MIR100HG Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I122556 Promoter/Enhancer 1 Ensembl ENCODE 550.8 -0.1 -80 0.4 CTCF POLR2A L3MBTL2 BACH1 MGA EZH2 MIR100HG PIR58507 GC11P122562 GC11P122524
GH11I122090 Promoter/Enhancer 1.3 Ensembl ENCODE dbSUPER 16.3 +458.1 458055 16.4 CTCF MXI1 USF1 FOXA2 EBF1 RAD21 JUND POLR2A ZNF143 RCOR1 GC11M122095 GC11M122101 MIR125B1 MIR100HG GC11P122103
GH11I122174 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE dbSUPER 10.6 +377.9 377927 8.4 BACH1 SIN3A ZNF316 POLR2A SCRT2 NFE2 FOSL2 FOS MAFK NFE2L2 BLID MIR100HG ENSG00000255219 GC11P122184 GC11M122182 GC11M122154 GC11M122156 MIR100
GH11I122185 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 10.6 +364.5 364497 13.3 FOXA2 JUN MAX CHD4 BATF RAD21 RFX5 ZKSCAN1 POLR2A ZNF143 GC11M122182 MIRLET7A2 BLID MIR100HG ENSG00000255219 GC11P122197 GC11P122184
GH11I122135 Enhancer 1.1 Ensembl ENCODE dbSUPER 11.6 +417.8 417844 7.3 FOXA2 JUN BRCA1 YY1 ETS1 GATA3 RERE POLR2A HNF4G FOSL2 BLID MIR100HG MIRLET7A2 GC11P122118
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR100HG on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR100HG Gene

Genomic Locations for MIR100HG Gene
chr11:122,028,327-122,556,721
(GRCh38/hg38)
Size:
528,395 bases
Orientation:
Minus strand
chr11:121,899,063-122,073,770
(GRCh37/hg19)

Genomic View for MIR100HG Gene

Genes around MIR100HG on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR100HG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR100HG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR100HG Gene

Proteins for MIR100HG Gene

Post-translational modifications for MIR100HG Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR100HG Gene

Domains & Families for MIR100HG Gene

Gene Families for MIR100HG Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR100HG: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR100HG Gene

Function for MIR100HG Gene

Phenotypes From GWAS Catalog for MIR100HG Gene

Phenotypes for MIR100HG Gene

GenomeRNAi human phenotypes for MIR100HG:
genes like me logo Genes that share phenotypes with MIR100HG: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR100HG Gene

Localization for MIR100HG Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR100HG Gene

Pathways & Interactions for MIR100HG Gene

SuperPathways for MIR100HG Gene

No Data Available

Interacting Proteins for MIR100HG Gene

Gene Ontology (GO) - Biological Process for MIR100HG Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR100HG Gene

Drugs & Compounds for MIR100HG Gene

No Compound Related Data Available

Transcripts for MIR100HG Gene

Unigene Clusters for MIR100HG Gene

Mir-100-let-7a-2 cluster host gene (non-protein coding):
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR100HG Gene

No ASD Table

Relevant External Links for MIR100HG Gene

GeneLoc Exon Structure for
MIR100HG
ECgene alternative splicing isoforms for
MIR100HG

Expression for MIR100HG Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR100HG Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR100HG Gene:

MIR100HG

SOURCE GeneReport for Unigene cluster for MIR100HG Gene:

Hs.44098
genes like me logo Genes that share expression patterns with MIR100HG: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR100HG Gene

Orthologs for MIR100HG Gene

Evolution for MIR100HG Gene

ENSEMBL:
Gene Tree for MIR100HG (if available)
TreeFam:
Gene Tree for MIR100HG (if available)

No data available for Orthologs for MIR100HG Gene

Paralogs for MIR100HG Gene

No data available for Paralogs for MIR100HG Gene

Variants for MIR100HG Gene

Sequence variations from dbSNP and Humsavar for MIR100HG Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000025309 -- 122,115,068(-) G/A intron_variant
rs1000060316 -- 122,147,981(-) T/G intron_variant
rs1000061641 -- 122,164,716(-) G/A intron_variant
rs1000082204 -- 122,201,724(-) C/T intron_variant
rs1000134757 -- 122,164,384(-) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR100HG Gene

Variant ID Type Subtype PubMed ID
dgv17n68 CNV gain 17160897
nsv477824 CNV novel sequence insertion 20440878
nsv476130 CNV novel sequence insertion 20440878
nsv1119921 CNV deletion 24896259
esv3310060 CNV mobile element insertion 20981092
esv275465 CNV gain+loss 21479260

Additional Variant Information for MIR100HG Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR100HG

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR100HG Gene

Disorders for MIR100HG Gene

Additional Disease Information for MIR100HG

No disorders were found for MIR100HG Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR100HG Gene

Publications for MIR100HG Gene

  1. LincRNAs MONC and MIR100HG act as oncogenes in acute megakaryoblastic leukemia. (PMID: 25027842) Emmrich S … Klusmann JH (Molecular cancer 2014) 2 3 58
  2. Evaluation of BLID and LOC399959 as candidate genes for high myopia in the Chinese Han population. (PMID: 21031016) Zhao F … Zhou X (Molecular vision 2010) 2 3 58
  3. Transcripts of unknown function in multiple-signaling pathways involved in human stem cell differentiation. (PMID: 19531736) Kikuchi K … Aizawa Y (Nucleic acids research 2009) 2 3 58
  4. Identification of linc-NeD125, a novel long non coding RNA that hosts miR-125b-1 and negatively controls proliferation of human neuroblastoma cells. (PMID: 26480000) Bevilacqua V … Caffarelli E (RNA biology 2015) 3 58
  5. A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1. (PMID: 19779542) Nakanishi H … Matsuda F (PLoS genetics 2009) 3 58

Products for MIR100HG Gene

Sources for MIR100HG Gene

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