Aliases for MIOS Gene
External Ids for MIOS Gene
Previous GeneCards Identifiers for MIOS Gene
GeneCards Summary for MIOS Gene
UniProtKB/Swiss-Prot for MIOS Gene
As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210).