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Aliases for MINPP1 Gene

Aliases for MINPP1 Gene

  • Multiple Inositol-Polyphosphate Phosphatase 1 2 3 5
  • Multiple Inositol Polyphosphate Histidine Phosphatase, 1 2 3
  • Inositol (1,3,4,5)-Tetrakisphosphate 3-Phosphatase 3 4
  • 2,3-Bisphosphoglycerate 3-Phosphatase 3 4
  • Ins(1,3,4,5)P(4) 3-Phosphatase 3 4
  • 2,3-BPG Phosphatase 3 4
  • MIPP 3 4
  • Multiple Inositol Polyphosphate Phosphatase 1 3
  • Multiple Inositol Polyphosphate Phosphatase 2 3
  • EC 3.1.3.62 4
  • EC 3.1.3.80 4
  • HIPER1 3
  • MINPP2 3

External Ids for MINPP1 Gene

Previous GeneCards Identifiers for MINPP1 Gene

  • GC10P088146
  • GC10P088486
  • GC10P089395
  • GC10P088929
  • GC10P089254
  • GC10P082898
  • GC10P089264

Summaries for MINPP1 Gene

Entrez Gene Summary for MINPP1 Gene

  • This gene encodes multiple inositol polyphosphate phosphatase; an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate; an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway.[provided by RefSeq, Sep 2009]

GeneCards Summary for MINPP1 Gene

MINPP1 (Multiple Inositol-Polyphosphate Phosphatase 1) is a Protein Coding gene. Diseases associated with MINPP1 include Thyroid Cancer, Nonmedullary, 2 and Familial Papillary Or Follicular Thyroid Carcinoma. Among its related pathways are Metabolism and superpathway of inositol phosphate compounds. Gene Ontology (GO) annotations related to this gene include phosphatase activity.

UniProtKB/Swiss-Prot for MINPP1 Gene

  • Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy (By similarity).

Gene Wiki entry for MINPP1 Gene

Additional gene information for MINPP1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MINPP1 Gene

Genomics for MINPP1 Gene

GeneHancer (GH) Regulatory Elements for MINPP1 Gene

Promoters and enhancers for MINPP1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J087503 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 650.7 +3.0 3003 5.4 MLX ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 E2F8 ZNF416 ZNF143 MIR4678 MINPP1 PAPSS2 GC10P087578
GH10J087500 Enhancer 1 ENCODE 650.7 -1.9 -1850 1.2 PKNOX1 FOXA2 MLX ARNT ARID4B FEZF1 DMAP1 YY1 SLC30A9 ZNF766 MINPP1 PIR60830 PAPSS2
GH10J088061 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 5.4 +562.3 562309 6.6 PKNOX1 FOXA2 SMAD1 IRF4 YY1 ZNF207 ATF7 RUNX3 RXRA JUNB PTEN KLLN MINPP1 NUTM2D MED6P1 GC10P088093 LOC105378415
GH10J087545 Enhancer 1 Ensembl ENCODE 8.1 +44.4 44376 2.9 PKNOX1 FEZF1 RAD21 TCF12 RUNX3 RXRA CEBPB REST ZEB2 NR2F2 PAPSS2 ENSG00000196566 MINPP1 GC10P087578 MIR4678
GH10J086534 Enhancer 1 Ensembl ENCODE 6.4 -966.6 -966641 2.5 FOXA2 ARID4B SIN3A DMAP1 ZNF48 YY1 ZNF614 EGR1 ZNF143 PRPF4 RNU6-780P MINPP1 LDB3 LOC105378408 LOC105378407
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MINPP1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the MINPP1 gene promoter:
  • FOXL1
  • Lmo2
  • Nkx2-5
  • HEN1
  • Tal-1
  • E47
  • AML1a
  • POU2F1
  • POU2F1a

Genomic Locations for MINPP1 Gene

Genomic Locations for MINPP1 Gene
chr10:87,502,792-87,553,461
(GRCh38/hg38)
Size:
50,670 bases
Orientation:
Plus strand
chr10:89,264,223-89,313,218
(GRCh37/hg19)
Size:
48,996 bases
Orientation:
Plus strand

Genomic View for MINPP1 Gene

Genes around MINPP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MINPP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MINPP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MINPP1 Gene

Proteins for MINPP1 Gene

  • Protein details for MINPP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UNW1-MINP1_HUMAN
    Recommended name:
    Multiple inositol polyphosphate phosphatase 1
    Protein Accession:
    Q9UNW1
    Secondary Accessions:
    • F5H683
    • O95172
    • O95286
    • Q59EJ2
    • Q9UGA3

    Protein attributes for MINPP1 Gene

    Size:
    487 amino acids
    Molecular mass:
    55051 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAD93056.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for MINPP1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MINPP1 Gene

Post-translational modifications for MINPP1 Gene

  • Glycosylation at isoforms=4481, posLast=242242, and isoforms=2, 342
  • Modification sites at PhosphoSitePlus

Other Protein References for MINPP1 Gene

No data available for DME Specific Peptides for MINPP1 Gene

Domains & Families for MINPP1 Gene

Gene Families for MINPP1 Gene

HGNC:
Human Protein Atlas (HPA):
  • Disease related genes
  • Enzymes
  • Plasma proteins
  • Potential drug targets
  • Predicted intracellular proteins
  • Predicted secreted proteins

Protein Domains for MINPP1 Gene

Graphical View of Domain Structure for InterPro Entry

Q9UNW1

UniProtKB/Swiss-Prot:

MINP1_HUMAN :
  • Belongs to the histidine acid phosphatase family. MINPP1 subfamily.
Family:
  • Belongs to the histidine acid phosphatase family. MINPP1 subfamily.
genes like me logo Genes that share domains with MINPP1: view

Function for MINPP1 Gene

Molecular function for MINPP1 Gene

UniProtKB/Swiss-Prot Function:
Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy (By similarity).
UniProtKB/Swiss-Prot CatalyticActivity:
Myo-inositol hexakisphosphate + H(2)O = myo-inositol pentakisphosphate (mixed isomers) + phosphate.
UniProtKB/Swiss-Prot CatalyticActivity:
2,3-bisphospho-D-glycerate + H(2)O = 2-phospho-D-glycerate + phosphate.
UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=0.61 mM for 2,3-bisphosphoglycerate {ECO:0000269 PubMed:18413611}; KM=90 uM for inositol hexakisphosphate {ECO:0000269 PubMed:16759730}; Vmax=15.8 nmol/min/mg enzyme with 2,3-bisphospho-D-glycerate as substrate {ECO:0000269 PubMed:18413611}; Vmax=6.2 nmol/min/mg enzyme with inositol hexakisphosphate as substrate {ECO:0000269 PubMed:16759730};
GENATLAS Biochemistry:
multiple inositol polyphosphate phosphatase 1,belonging to a distinct group of histidine phosphatase

Enzyme Numbers (IUBMB) for MINPP1 Gene

Phenotypes From GWAS Catalog for MINPP1 Gene

Gene Ontology (GO) - Molecular Function for MINPP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003993 acid phosphatase activity IBA --
GO:0004446 inositol-hexakisphosphate phosphatase activity IEA --
GO:0016787 hydrolase activity IEA --
GO:0016791 phosphatase activity IEA --
GO:0030351 inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity TAS --
genes like me logo Genes that share ontologies with MINPP1: view
genes like me logo Genes that share phenotypes with MINPP1: view

Human Phenotype Ontology for MINPP1 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for MINPP1 Gene

MGI Knock Outs for MINPP1:

Animal Model Products

CRISPR Products

miRNA for MINPP1 Gene

Clone Products

No data available for Transcription Factor Targets and HOMER Transcription for MINPP1 Gene

Localization for MINPP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MINPP1 Gene

Endoplasmic reticulum lumen.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MINPP1 gene
Compartment Confidence
extracellular 5
endoplasmic reticulum 5
mitochondrion 2
cytosol 2
peroxisome 1
lysosome 1

Gene Ontology (GO) - Cellular Components for MINPP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum TAS 10087200
GO:0005788 endoplasmic reticulum lumen TAS --
GO:0070062 extracellular exosome HDA 23533145
genes like me logo Genes that share ontologies with MINPP1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for MINPP1 Gene

Pathways & Interactions for MINPP1 Gene

genes like me logo Genes that share pathways with MINPP1: view

Gene Ontology (GO) - Biological Process for MINPP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001503 ossification NAS 9923613
GO:0006470 protein dephosphorylation IEA --
GO:0006797 polyphosphate metabolic process TAS 10087200
GO:0016311 dephosphorylation IEA --
GO:0030282 bone mineralization NAS 9923613
genes like me logo Genes that share ontologies with MINPP1: view

No data available for SIGNOR curated interactions for MINPP1 Gene

Drugs & Compounds for MINPP1 Gene

(4) Drugs for MINPP1 Gene - From: HMDB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Phosphoric acid Approved Pharma 0
Water Approved Pharma 0
2-phospho-D-glyceric acid Experimental Pharma 0

(6) Additional Compounds for MINPP1 Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
2,3-Diphosphoglyceric acid
  • 2,3-bisphospho-D-Glycerate
  • 2,3-Bisphosphoglyceric acid
  • 2,3-BPG
  • 2,3-disphospho-D-Glycerate
  • D-Greenwald ester
138-81-8
Inositol 1,3,4,5-tetraphosphate
  • 1,3,4,5-Tetrakis(dihydrogen phosphate) myo-inositol
  • 1D-myo-Inositol 1,3,4,5-tetrakis(dihydrogen phosphate)
  • 1D-myo-Inositol 1,3,4,5-tetrakisphosphate
  • D-myo-Inositol 1,3,4,5-tetrakisphosphate
  • Inositol 1,3,4,5-tetrakis(phosphate)
102850-29-3
Inositol 1,4,5-trisphosphate
  • 1,4,5-Insp3
  • D-myo-Inositol 1,4,5-trisphosphate
  • D-myo-INOSITOL-1,4,5-triphosphATE
  • Ins(1,4,5)P3
  • InsP3
88269-39-0
Myo-inositol hexakisphosphate
  • 1D-myo-Inositol 1,2,3,4,5,6-hexakisphosphate
  • 1D-myo-Inositol hexakisphosphate
  • D-myo-Inositol 1,2,3,4,5,6-hexakisphosphate
  • Inositol 1,2,3,4,5,6-hexakisphosphate
  • myo-Inositol 1,2,3,4,5,6-hexakisphosphate
83-86-3
Phosphate
  • [po(OH)3]
  • Acide phosphorique
  • Acidum phosphoricum
  • H3PO4
  • Orthophosphoric acid
14265-44-2
genes like me logo Genes that share compounds with MINPP1: view

Transcripts for MINPP1 Gene

Unigene Clusters for MINPP1 Gene

Multiple inositol-polyphosphate phosphatase 1:
Representative Sequences:

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MINPP1 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c
SP1: -
SP2:
SP3: - -
SP4:

Relevant External Links for MINPP1 Gene

GeneLoc Exon Structure for
MINPP1
ECgene alternative splicing isoforms for
MINPP1

Expression for MINPP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MINPP1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for MINPP1 Gene

This gene is overexpressed in Serum (50.8) and Plasma (9.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MINPP1 Gene



NURSA nuclear receptor signaling pathways regulating expression of MINPP1 Gene:

MINPP1

SOURCE GeneReport for Unigene cluster for MINPP1 Gene:

Hs.121260

mRNA Expression by UniProt/SwissProt for MINPP1 Gene:

Q9UNW1-MINP1_HUMAN
Tissue specificity: Widely expressed with highest levels in kidney, liver and placenta.

Evidence on tissue expression from TISSUES for MINPP1 Gene

  • Nervous system(4.4)
  • Bone marrow(4.2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for MINPP1 Gene

Germ Layers:
  • endoderm
Systems:
  • endocrine
Regions:
Head and neck:
  • neck
  • thyroid
genes like me logo Genes that share expression patterns with MINPP1: view

No data available for mRNA differential expression in normal tissues and Protein tissue co-expression partners for MINPP1 Gene

Orthologs for MINPP1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for MINPP1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MINPP1 34 33
  • 99.11 (n)
OneToOne
cow
(Bos Taurus)
Mammalia MINPP1 34 33
  • 88.61 (n)
OneToOne
dog
(Canis familiaris)
Mammalia MINPP1 34 33
  • 88.56 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Minpp1 33
  • 82.88 (n)
mouse
(Mus musculus)
Mammalia Minpp1 16 34 33
  • 81.7 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia MINPP1 34
  • 73 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MINPP1 34
  • 67 (a)
OneToOne
chicken
(Gallus gallus)
Aves MINPP1 34 33
  • 66.43 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MINPP1 34
  • 49 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia minpp1 33
  • 59.95 (n)
zebrafish
(Danio rerio)
Actinopterygii minpp1b 34 33
  • 55.09 (n)
OneToMany
minpp1a 34
  • 44 (a)
OneToMany
zgc56080 33
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.485 33
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003555 33
  • 43.47 (n)
fruit fly
(Drosophila melanogaster)
Insecta Mipp2 34 35 33
  • 42.43 (n)
OneToMany
Mipp1 34
  • 24 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes PHO11 36
thale cress
(Arabidopsis thaliana)
eudicotyledons AT1G09870 33
  • 42.09 (n)
rice
(Oryza sativa)
Liliopsida Os03g0818100 33
  • 43.56 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 38 (a)
OneToOne
Species where no ortholog for MINPP1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MINPP1 Gene

ENSEMBL:
Gene Tree for MINPP1 (if available)
TreeFam:
Gene Tree for MINPP1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for MINPP1: view image

Paralogs for MINPP1 Gene

No data available for Paralogs for MINPP1 Gene

Variants for MINPP1 Gene

Sequence variations from dbSNP and Humsavar for MINPP1 Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs104894171 pathogenic, Thyroid cancer, follicular, Thyroid cancer, non-medullary, 2 (NMTC2) [MIM:188470] 87,508,507(+) A/G coding_sequence_variant, missense_variant
rs119486096 pathogenic, Thyroid cancer, follicular, Thyroid cancer, non-medullary, 2 (NMTC2) [MIM:188470] 87,505,037(+) C/T 5_prime_UTR_variant, coding_sequence_variant, genic_upstream_transcript_variant, missense_variant, upstream_transcript_variant
rs1000014698 -- 87,517,281(+) T/G genic_downstream_transcript_variant, intron_variant
rs1000238775 -- 87,507,408(+) C/G genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000362068 -- 87,549,726(+) G/A genic_downstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for MINPP1 Gene

Variant ID Type Subtype PubMed ID
dgv1332n54 CNV loss 21841781
dgv166n67 CNV gain 20364138
dgv24n73 CNV deletion 24416366
dgv493n106 CNV deletion 24896259
esv1003677 CNV loss 20482838
esv2657019 CNV deletion 23128226
esv26704 CNV gain+loss 19812545
esv2759774 CNV gain+loss 17122850
esv3261718 CNV deletion 24192839
esv3546628 CNV deletion 23714750
esv3624109 CNV loss 21293372
esv3624110 CNV loss 21293372
esv3891880 CNV gain 25118596
nsv428236 CNV loss 18775914
nsv508598 CNV deletion 20534489
nsv510993 OTHER complex 20534489
nsv511458 CNV loss 21212237
nsv512173 CNV loss 21212237
nsv551825 CNV gain 21841781
nsv551826 CNV loss 21841781
nsv551827 CNV gain 21841781
nsv551830 CNV gain+loss 21841781
nsv819899 CNV loss 19587683
nsv820304 CNV gain 19587683
nsv821205 CNV deletion 20802225
nsv825496 CNV loss 20364138
nsv825497 CNV gain 20364138
nsv825499 CNV loss 20364138
nsv950987 CNV duplication 24416366

Variation tolerance for MINPP1 Gene

Residual Variation Intolerance Score: 12.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.59; 12.62% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MINPP1 Gene

Human Gene Mutation Database (HGMD)
MINPP1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MINPP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MINPP1 Gene

Disorders for MINPP1 Gene

MalaCards: The human disease database

(3) MalaCards diseases for MINPP1 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, and DISEASES

- elite association - COSMIC cancer census association via MalaCards

UniProtKB/Swiss-Prot

MINP1_HUMAN
  • Thyroid cancer, non-medullary, 2 (NMTC2) [MIM:188470]: A form of non-medullary thyroid cancer (NMTC), a cancer characterized by tumors originating from the thyroid follicular cells. NMTCs represent approximately 95% of all cases of thyroid cancer and are classified into papillary, follicular, Hurthle cell, and anaplastic neoplasms. {ECO:0000269 PubMed:11297621}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.

Additional Disease Information for MINPP1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with MINPP1: view

No data available for Genatlas for MINPP1 Gene

Publications for MINPP1 Gene

  1. Multiple inositol polyphosphate phosphatase: evolution as a distinct group within the histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19. (PMID: 10087200) Chi H … Reynolds PR (Genomics 1999) 2 3 4 22 58
  2. Somatic mutation and germline variants of MINPP1, a phosphatase gene located in proximity to PTEN on 10q23.3, in follicular thyroid carcinomas. (PMID: 11297621) Gimm O … Eng C (The Journal of clinical endocrinology and metabolism 2001) 3 4 22 58
  3. The human and rat forms of multiple inositol polyphosphate phosphatase: functional homology with a histidine acid phosphatase up-regulated during endochondral ossification. (PMID: 9923613) Caffrey JJ … Shears SB (FEBS letters 1999) 3 4 22 58
  4. A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. (PMID: 20304771) Newman AB … Murabito JM (The journals of gerontology. Series A, Biological sciences and medical sciences 2010) 3 44 58
  5. Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the regulatory capacity of the Rapoport-Luebering glycolytic shunt. (PMID: 18413611) Cho J … Shears SB (Proceedings of the National Academy of Sciences of the United States of America 2008) 3 4 58

Products for MINPP1 Gene

Sources for MINPP1 Gene

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