Aliases for MIF4GD Gene
External Ids for MIF4GD Gene
Previous HGNC Symbols for MIF4GD Gene
Previous GeneCards Identifiers for MIF4GD Gene
This gene encodes a protein which interacts with the N-terminus of the stem-loop binding protein (SLBP) and the 3' end of histone mRNA. This interaction facilitates the activation of histone mRNA translation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
GeneCards Summary for MIF4GD Gene
MIF4GD (MIF4G Domain Containing) is a Protein Coding gene. Diseases associated with MIF4GD include Retinitis Pigmentosa 70. Gene Ontology (GO) annotations related to this gene include RNA binding and protein C-terminus binding. An important paralog of this gene is CTIF.
UniProtKB/Swiss-Prot Summary for MIF4GD Gene
Functions in replication-dependent translation of histone mRNAs which differ from other eukaryotic mRNAs in that they do not end with a poly-A tail but a stem-loop. May participate in circularizing those mRNAs specifically enhancing their translation.