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MICALL1 (MICAL Like 1) is a Protein Coding gene. Diseases associated with MICALL1 include Diarrhea 2, With Microvillus Atrophy. Gene Ontology (GO) annotations related to this gene include identical protein binding and phosphatidic acid binding. An important paralog of this gene is MICALL2.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 19864458 |
GO:0017137 | Rab GTPase binding | IEA,IPI | 19864458 |
GO:0042802 | identical protein binding | IPI | 23596323 |
GO:0045296 | cadherin binding | HDA | 25468996 |
GO:0046872 | metal ion binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005768 | endosome | IEA | -- |
GO:0005769 | NOT early endosome | IDA | 21795389 |
GO:0005770 | late endosome | IDA | 21795389 |
GO:0005802 | NOT trans-Golgi network | IDA | 21795389 |
GO:0005815 | microtubule organizing center | IBA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006612 | protein targeting to membrane | IMP | 19864458 |
GO:0006897 | endocytosis | IMP | 20801876 |
GO:0006898 | receptor-mediated endocytosis | IMP | 21795389 |
GO:0015031 | protein transport | IEA | -- |
GO:0030036 | actin cytoskeleton organization | IBA | -- |
ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | · | 13c | ^ | 14a | · | 14b | ^ | 15a | · | 15b | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP2: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
SP3: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP4: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
SP5: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP6: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP9: |
ExUns: | 20 |
---|---|
SP1: | |
SP2: | |
SP3: | |
SP4: | |
SP5: | |
SP6: | |
SP7: | |
SP8: | |
SP9: |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | MICALL1 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | MICALL1 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | MICALL1 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Micall1 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Micall1 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | MICALL1 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | MICALL1 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | MICALL1 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | MICALL1 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | micall1 30 |
|
||
Str.16017 30 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.30156 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | micall1 30 31 |
|
OneToMany | |
MICALL1 (1 of 3) 31 |
|
OneToMany | |||
MICALL1 (3 of 3) 31 |
|
OneToMany | |||
Worm (Caenorhabditis elegans) |
Secernentea | T15B12.1 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToOne |
SNP ID | Clinical significance and condition | Chr 22 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
VAR_036192 | A breast cancer sample | p.Glu817Lys | |||
rs2272829 | - | p.Pro583Leu | |||
rs34834842 | - | p.His685Arg | |||
rs9610875 | - | p.Ala519Ser |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv3575479 | CNV | gain | 25503493 |
esv3893482 | CNV | gain | 25118596 |
nsv1144971 | CNV | deletion | 24896259 |
Disorder | Aliases | PubMed IDs |
---|---|---|
diarrhea 2, with microvillus atrophy |
|
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