Aliases for MICALL1 Gene
External Ids for MICALL1 Gene
Previous GeneCards Identifiers for MICALL1 Gene
GeneCards Summary for MICALL1 Gene
MICALL1 (MICAL Like 1) is a Protein Coding gene. Diseases associated with MICALL1 include Diarrhea 2, With Microvillus Atrophy. Gene Ontology (GO) annotations related to this gene include identical protein binding and phosphatidic acid binding. An important paralog of this gene is MICALL2.
UniProtKB/Swiss-Prot Summary for MICALL1 Gene
Probable lipid-binding protein with higher affinity for phosphatidic acid, a lipid enriched in recycling endosome membranes. On endosome membranes, may act as a downstream effector of Rab proteins recruiting cytosolic proteins to regulate membrane tubulation. May be involved in a late step of receptor-mediated endocytosis regulating for instance endocytosed-EGF receptor trafficking. Alternatively, may regulate slow endocytic recycling of endocytosed proteins back to the plasma membrane. May indirectly play a role in neurite outgrowth.