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MICAL3 (Microtubule Associated Monooxygenase, Calponin And LIM Domain Containing 3) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include actin binding and Rab GTPase binding. An important paralog of this gene is MICAL2.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003779 | actin binding | ISS | -- |
GO:0004497 | monooxygenase activity | IEA | -- |
GO:0005515 | protein binding | IEA | -- |
GO:0016491 | oxidoreductase activity | IEA | -- |
GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | IEA,ISS | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA,IDA | 24440334 |
GO:0005654 | nucleoplasm | IDA | -- |
GO:0005737 | cytoplasm | IEA | -- |
GO:0005815 | microtubule organizing center | IBA | -- |
GO:0005819 | spindle | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006887 | exocytosis | IEA | -- |
GO:0007010 | cytoskeleton organization | IDA | 24440334 |
GO:0007049 | cell cycle | IEA | -- |
GO:0030036 | actin cytoskeleton organization | IBA | -- |
GO:0030042 | actin filament depolymerization | ISS | -- |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | MICAL3 30 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
Dog (Canis familiaris) |
Mammalia | MICAL3 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Mical3 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Mical3 30 17 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | MICAL3 30 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | MICAL3 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | MICAL3 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | MICAL3 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | mical3 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | mical3a 30 31 31 |
|
OneToMany | |
mical3b 31 |
|
OneToMany | |||
Dr.14768 30 |
|
||||
Fruit Fly (Drosophila melanogaster) |
Insecta | Mical 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 22 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
710987 | Benign: not provided | 17,893,880(-) | C/T | MISSENSE_VARIANT | |
715940 | Benign: not provided | 17,791,210(-) | C/A | SYNONYMOUS_VARIANT | |
730633 | Benign: not provided | 17,896,769(-) | G/A | SYNONYMOUS_VARIANT | |
786693 | Benign: not provided | 17,818,424(-) | G/A | MISSENSE_VARIANT | |
788040 | Benign: not provided | 17,822,038(-) | T/C | MISSENSE_VARIANT |
No disorders were found for MICAL3 Gene.