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Aliases for MICAL3 Gene

Aliases for MICAL3 Gene

  • Microtubule Associated Monooxygenase, Calponin And LIM Domain Containing 3 2 3 5
  • Molecule Interacting With CasL Protein 3 3 4
  • MICAL-3 3 4
  • [F-Actin]-Methionine Sulfoxide Oxidase MICAL3 3
  • Protein-Methionine Sulfoxide Oxidase MICAL3 3
  • Flavoprotein Oxidoreductase MICAL3 3
  • [F-Actin]-Monooxygenase MICAL3 3
  • F-Actin-Monooxygenase MICAL3 3
  • Protein MICAL-3 3
  • EC 1.14.13.225 4
  • KIAA0819 4
  • KIAA1364 4

External Ids for MICAL3 Gene

Previous GeneCards Identifiers for MICAL3 Gene

  • GC22M016696
  • GC22M016697
  • GC22M016691
  • GC22M016650
  • GC22M018271
  • GC22M002084

Summaries for MICAL3 Gene

GeneCards Summary for MICAL3 Gene

MICAL3 (Microtubule Associated Monooxygenase, Calponin And LIM Domain Containing 3) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include actin binding and Rab GTPase binding. An important paralog of this gene is MICAL2.

UniProtKB/Swiss-Prot for MICAL3 Gene

  • Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in actin filament disassembly and preventing repolymerization. In the absence of actin, it also functions as a NADPH oxidase producing H(2)O(2). Seems to act as Rab effector protein and plays a role in vesicle trafficking. Involved in exocytic vesicles tethering and fusion: the monooxygenase activity is required for this process and implicates RAB8A associated with exocytotic vesicles. Required for cytokinesis. Contributes to stabilization and/or maturation of the intercellular bridge independently of its monooxygenase activity. Promotes recruitment of Rab8 and ERC1 to the intercellular bridge, and together these proteins are proposed to function in timely abscission.

Gene Wiki entry for MICAL3 Gene

Additional gene information for MICAL3 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MICAL3 Gene

Genomics for MICAL3 Gene

GeneHancer (GH) Regulatory Elements for MICAL3 Gene

Promoters and enhancers for MICAL3 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J018066 Promoter/Enhancer 1.9 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 661.8 -44.4 -44378 5.5 HDGF FOXA2 ARID4B ZNF335 IKZF2 MCM3 RXRA ELF1 PPARG ZNF148 MICAL3 ENSG00000093100 USP18 DGCR11 GC22P018073 LOC105372853
GH22J018022 Promoter/Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 654.3 +0.5 525 2.3 ZFP64 SIN3A ZNF2 YY1 GLIS2 ZNF143 RUNX3 REST ZNF610 GLIS1 MICAL3 LINC01634 RHEBP3
GH22J017999 Promoter/Enhancer 1.8 Ensembl ENCODE dbSUPER 23.1 +23.7 23739 3.2 HDGF PKNOX1 CLOCK SMAD1 MLX ARNT ARID4B SIN3A ZNF2 YY1 MICAL3 ENSG00000093100 HDHD5-AS1 ENSG00000236890 HDHD5 ENSG00000234913 ENSG00000235445
GH22J017919 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 19.4 +102.7 102737 5.2 HDGF PKNOX1 SMAD1 ATF1 YY1 TCF12 ZNF121 GLIS2 CBX5 GATA2 MICAL3 ENSG00000093100 PIR41738 GC22M017948 PIR51874
GH22J017971 Enhancer 1.3 Ensembl ENCODE dbSUPER 23.8 +51.6 51638 3 ARID4B SIN3A DMAP1 ETS1 RXRA MXD4 PPARG KAT8 NFIL3 MIER3 MICAL3 ENSG00000093100 HDHD5-AS1 MIR648 PIR53397
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MICAL3 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the MICAL3 gene promoter:
  • GATA-3
  • GATA-2
  • GATA-1
  • STAT5A
  • ER-alpha
  • STAT5B
  • RORalpha2
  • RORalpha1
  • HSF2
  • POU2F1

Genomic Locations for MICAL3 Gene

Genomic Locations for MICAL3 Gene
chr22:17,787,649-18,024,559
(GRCh38/hg38)
Size:
236,911 bases
Orientation:
Minus strand
chr22:18,270,415-18,507,325
(GRCh37/hg19)
Size:
236,911 bases
Orientation:
Minus strand

Genomic View for MICAL3 Gene

Genes around MICAL3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MICAL3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MICAL3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MICAL3 Gene

Proteins for MICAL3 Gene

  • Protein details for MICAL3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7RTP6-MICA3_HUMAN
    Recommended name:
    [F-actin]-monooxygenase MICAL3
    Protein Accession:
    Q7RTP6
    Secondary Accessions:
    • B2RXJ5
    • E9PEF0
    • O94909
    • Q5U4P4
    • Q6ICK4
    • Q96DF2
    • Q9P2I3

    Protein attributes for MICAL3 Gene

    Size:
    2002 amino acids
    Molecular mass:
    224295 Da
    Cofactor:
    Name=FAD; Xref=ChEBI:CHEBI:57692;
    Quaternary structure:
    • Interacts with RAB1B, RAB8A, RAB10, RAB13 and RAB15 (in their GTP-bound forms); binding to RAB1B is of low affinity compared to other Rab proteins; at least in case of RAB8A can bind 2 molecules of RAB8A simultaneously through a high and a low affinity binding site, respectively. Interacts with ERC1 and RAB8A; may bridge ERC1 with RAB8A. Interacts with KIF23 and ERC1; enhances the interaction between KIF23 and ERC1. Interacts with NINL isoform 2.

    Three dimensional structures from OCA and Proteopedia for MICAL3 Gene

    Alternative splice isoforms for MICAL3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MICAL3 Gene

Post-translational modifications for MICAL3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for MICAL3 Gene

Domains & Families for MICAL3 Gene

Gene Families for MICAL3 Gene

HGNC:
Human Protein Atlas (HPA):
  • Enzymes
  • Predicted intracellular proteins
  • Predicted membrane proteins

Suggested Antigen Peptide Sequences for MICAL3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q7RTP6

UniProtKB/Swiss-Prot:

MICA3_HUMAN :
  • The bivalent Mical/EHBP Rab binding (bMERB) domain, mediates binding to predominantly Rab8, Rab10, Rab10, Rab13 and Rab15 (in their GTP-bound forms).
  • Belongs to the Mical family.
Domain:
  • The bivalent Mical/EHBP Rab binding (bMERB) domain, mediates binding to predominantly Rab8, Rab10, Rab10, Rab13 and Rab15 (in their GTP-bound forms).
Family:
  • Belongs to the Mical family.
genes like me logo Genes that share domains with MICAL3: view

Function for MICAL3 Gene

Molecular function for MICAL3 Gene

UniProtKB/Swiss-Prot Function:
Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in actin filament disassembly and preventing repolymerization. In the absence of actin, it also functions as a NADPH oxidase producing H(2)O(2). Seems to act as Rab effector protein and plays a role in vesicle trafficking. Involved in exocytic vesicles tethering and fusion: the monooxygenase activity is required for this process and implicates RAB8A associated with exocytotic vesicles. Required for cytokinesis. Contributes to stabilization and/or maturation of the intercellular bridge independently of its monooxygenase activity. Promotes recruitment of Rab8 and ERC1 to the intercellular bridge, and together these proteins are proposed to function in timely abscission.
UniProtKB/Swiss-Prot CatalyticActivity:
[F-actin]-L-methionine + NADPH + O(2) + H(+) = [F-actin]-L-methionine-(R)-S-oxide + NADP(+) + H(2)O.

Enzyme Numbers (IUBMB) for MICAL3 Gene

Phenotypes From GWAS Catalog for MICAL3 Gene

Gene Ontology (GO) - Molecular Function for MICAL3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003779 actin binding ISS --
GO:0004497 monooxygenase activity IEA --
GO:0005515 protein binding IEA --
GO:0016491 oxidoreductase activity IEA --
GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen ISS --
genes like me logo Genes that share ontologies with MICAL3: view
genes like me logo Genes that share phenotypes with MICAL3: view

Animal Model Products

  • Taconic Biosciences Mouse Models for MICAL3

miRNA for MICAL3 Gene

Clone Products

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MICAL3 Gene

Localization for MICAL3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MICAL3 Gene

Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Nucleus. Midbody. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, cilium basal body. Note=Mainly localizes in the nucleus. {ECO:0000269 PubMed:24440334}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MICAL3 gene
Compartment Confidence
nucleus 5
cytosol 5
plasma membrane 4
cytoskeleton 4
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (4)
  • Cytosol (1)
  • Plasma membrane (1)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for MICAL3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA,IDA 24440334
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IEA --
GO:0005819 spindle IEA --
GO:0005829 cytosol IDA --
genes like me logo Genes that share ontologies with MICAL3: view

Pathways & Interactions for MICAL3 Gene

SuperPathways for MICAL3 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MICAL3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006887 exocytosis IEA --
GO:0007010 cytoskeleton organization IDA 24440334
GO:0007049 cell cycle IEA --
GO:0030042 actin filament depolymerization ISS --
GO:0051301 cell division IEA --
genes like me logo Genes that share ontologies with MICAL3: view

No data available for Pathways by source and SIGNOR curated interactions for MICAL3 Gene

Drugs & Compounds for MICAL3 Gene

(3) Drugs for MICAL3 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
FAD Approved Pharma 0
Oxygen Approved, Vet_approved Pharma 0
Water Approved Pharma 0

(2) Additional Compounds for MICAL3 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
NADP
  • beta-Nicotinamide adenine dinucleotide phosphate
  • NADP+
  • Nicotinamide adenine dinucleotide phosphate
  • Oxidized nicotinamide-adenine dinucleotide phosphate
  • TPN
53-59-8
nadph
  • 2'-(Dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-b-D-ribofuranosylnicotinamide
  • 2'-(Dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide
  • Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-D-ribofuranosyl-3-pyridinecarboxamide
  • Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosyl-3-pyridinecarboxamide
  • b-NADPH
53-57-6
genes like me logo Genes that share compounds with MICAL3: view

Transcripts for MICAL3 Gene

Unigene Clusters for MICAL3 Gene

Microtubule associated monoxygenase, calponin and LIM domain containing 3:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MICAL3 Gene

No ASD Table

Relevant External Links for MICAL3 Gene

GeneLoc Exon Structure for
MICAL3
ECgene alternative splicing isoforms for
MICAL3

Expression for MICAL3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MICAL3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for MICAL3 Gene

This gene is overexpressed in Blymphocyte (16.2), Fetal Brain (8.8), Frontal cortex (7.1), and Peripheral blood mononuclear cells (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for MICAL3 Gene



Protein tissue co-expression partners for MICAL3 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of MICAL3 Gene:

MICAL3

SOURCE GeneReport for Unigene cluster for MICAL3 Gene:

Hs.528024

mRNA Expression by UniProt/SwissProt for MICAL3 Gene:

Q7RTP6-MICA3_HUMAN
Tissue specificity: Ubiquitous.

Evidence on tissue expression from TISSUES for MICAL3 Gene

  • Nervous system(4.8)
  • Liver(4.3)
  • Pancreas(4.1)
  • Lung(2)
genes like me logo Genes that share expression patterns with MICAL3: view

No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for MICAL3 Gene

Orthologs for MICAL3 Gene

This gene was present in the common ancestor of animals.

Orthologs for MICAL3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MICAL3 34 33
  • 98.58 (n)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 94 (a)
OneToMany
-- 34
  • 67 (a)
OneToMany
-- 34
  • 55 (a)
OneToMany
-- 34
  • 55 (a)
OneToMany
-- 34
  • 39 (a)
OneToMany
dog
(Canis familiaris)
Mammalia MICAL3 34 33
  • 86.74 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mical3 33
  • 84.53 (n)
mouse
(Mus musculus)
Mammalia Mical3 16 34 33
  • 84.49 (n)
cow
(Bos Taurus)
Mammalia MICAL3 34 33
  • 83.2 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MICAL3 34
  • 71 (a)
OneToOne
chicken
(Gallus gallus)
Aves MICAL3 34 33
  • 72.37 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MICAL3 34
  • 68 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia mical3 33
  • 67.39 (n)
zebrafish
(Danio rerio)
Actinopterygii mical3a 34 34 33
  • 66.43 (n)
OneToMany
mical3b 34
  • 55 (a)
OneToMany
Dr.14768 33
fruit fly
(Drosophila melanogaster)
Insecta Mical 34
  • 14 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 52 (a)
OneToMany
Species where no ortholog for MICAL3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MICAL3 Gene

ENSEMBL:
Gene Tree for MICAL3 (if available)
TreeFam:
Gene Tree for MICAL3 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for MICAL3: view image

Paralogs for MICAL3 Gene

(7) SIMAP similar genes for MICAL3 Gene using alignment to 9 proteins:

  • MICA3_HUMAN
  • C9J922_HUMAN
  • E9PP85_HUMAN
  • J3KRP8_HUMAN
  • J3KSK6_HUMAN
  • J3KTB6_HUMAN
  • J3QLA3_HUMAN
  • J3QQT0_HUMAN
  • J3QR21_HUMAN
genes like me logo Genes that share paralogs with MICAL3: view

Variants for MICAL3 Gene

Sequence variations from dbSNP and Humsavar for MICAL3 Gene

SNP ID Clin Chr 22 pos Variation AA Info Type
rs1000010389 -- 17,949,408(-) C/T genic_upstream_transcript_variant, intron_variant
rs1000022597 -- 17,823,122(-) T/G genic_downstream_transcript_variant, intron_variant
rs1000031035 -- 17,983,006(-) C/A genic_upstream_transcript_variant, intron_variant
rs1000069258 -- 17,917,815(-) G/A/C genic_upstream_transcript_variant, intron_variant
rs1000071686 -- 17,975,992(-) T/C genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for MICAL3 Gene

Variant ID Type Subtype PubMed ID
dgv1279e212 CNV loss 25503493
dgv19e194 CNV deletion 18987734
dgv2430n106 CNV deletion 24896259
dgv2561e59 CNV duplication 20981092
dgv730e201 CNV deletion 23290073
dgv816e199 CNV deletion 23128226
esv1048298 CNV deletion 17803354
esv1410721 CNV deletion 17803354
esv1920921 CNV deletion 18987734
esv2421190 CNV deletion 18987734
esv2493326 CNV deletion 19546169
esv2543355 CNV deletion 19546169
esv2723954 CNV deletion 23290073
esv2723955 CNV deletion 23290073
esv2723957 CNV deletion 23290073
esv2723959 CNV deletion 23290073
esv2723960 CNV deletion 23290073
esv2723961 CNV deletion 23290073
esv275264 CNV loss 21479260
esv27985 CNV gain+loss 19812545
esv29318 CNV loss 19812545
esv3450955 CNV duplication 20981092
esv3557912 CNV deletion 23714750
esv3575408 CNV gain 25503493
esv3893428 CNV loss 25118596
esv3910 CNV loss 18987735
esv993104 CNV deletion 20482838
nsv1065486 CNV loss 25217958
nsv1072614 CNV deletion 25765185
nsv1109449 CNV deletion 24896259
nsv1112371 CNV deletion 24896259
nsv1148898 CNV deletion 26484159
nsv1153159 CNV deletion 26484159
nsv191257 CNV deletion 16902084
nsv3555 CNV insertion 18451855
nsv3556 CNV insertion 18451855
nsv428385 CNV gain+loss 18775914
nsv472319 CNV novel sequence insertion 20440878
nsv476144 CNV novel sequence insertion 20440878
nsv509806 CNV insertion 20534489
nsv526826 CNV gain 19592680
nsv527393 CNV loss 19592680
nsv588119 CNV loss 21841781
nsv834119 CNV loss 17160897
nsv834120 CNV loss 17160897
nsv834121 CNV gain 17160897
nsv955484 CNV deletion 24416366
nsv962752 CNV duplication 23825009

Variation tolerance for MICAL3 Gene

Residual Variation Intolerance Score: 78.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.11; 84.56% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MICAL3 Gene

Human Gene Mutation Database (HGMD)
MICAL3
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MICAL3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MICAL3 Gene

Disorders for MICAL3 Gene

Additional Disease Information for MICAL3

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MICAL3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MICAL3 Gene

Publications for MICAL3 Gene

  1. MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion. (PMID: 12110185) Terman JR … Kolodkin AL (Cell 2002) 2 3 4 58
  2. MICAL3 Flavoprotein Monooxygenase Forms a Complex with Centralspindlin and Regulates Cytokinesis. (PMID: 27528609) Liu Q … Akhmanova A (The Journal of biological chemistry 2016) 3 4 58
  3. The Ciliopathy Protein CC2D2A Associates with NINL and Functions in RAB8-MICAL3-Regulated Vesicle Trafficking. (PMID: 26485645) Bachmann-Gagescu R … van Wijk E (PLoS genetics 2015) 3 4 58
  4. Redox modification of nuclear actin by MICAL-2 regulates SRF signaling. (PMID: 24440334) Lundquist MR … Jaffrey SR (Cell 2014) 3 4 58
  5. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. (PMID: 22001757) Chambers JC … Kooner JS (Nature genetics 2011) 3 44 58

Products for MICAL3 Gene

Sources for MICAL3 Gene

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