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Aliases for MGC16025 Gene

Subcategory (RNA class) for MGC16025 Gene

lncRNA

Quality Score for this RNA gene is

13

Aliases for MGC16025 Gene

  • Uncharacterized LOC85009 3
  • Uncharacterized Protein MGC16025 13

External Ids for MGC16025 Gene

ORGUL Members for MGC16025 Gene

Previous GeneCards Identifiers for MGC16025 Gene

  • GC02M238057
  • GC02M238688
  • GC02M240030
  • GC02M240327
  • GC02U900722
  • GC02M239781
  • GC02M240115

Summaries for MGC16025 Gene

GeneCards Summary for MGC16025 Gene

MGC16025 (Uncharacterized LOC85009) is an RNA Gene, and is affiliated with the lncRNA class. Among its related pathways are PEDF Induced Signaling and CREB Pathway.

Additional gene information for MGC16025 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MGC16025 Gene

Genomics for MGC16025 Gene

GeneHancer (GH) Regulatory Elements for MGC16025 Gene

Promoters and enhancers for MGC16025 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J239194 Enhancer 0.4 Ensembl dbSUPER 600.7 +0.3 256 1.2 MGC16025 HDAC4-AS1 HDAC4 GC02M239160
GH02J239193 Enhancer 0.4 Ensembl dbSUPER 600.7 +1.9 1856 0.4 MGC16025 GC02M239160 HDAC4
GH02J239196 Enhancer 0.4 Ensembl dbSUPER 600.7 -0.6 -644 0.2 MGC16025 HDAC4 HDAC4-AS1 GC02M239271
GH02J239220 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE dbSUPER 0.3 -29.2 -29212 8.1 ELF3 CEBPG MAFK TFE3 SP1 HNF1A ZNF384 PKNOX1 RXRA ZIC2 HDAC4 HDAC4-AS1 MGC16025 GC02M239271
GH02J239238 Promoter/Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 0.3 -44.7 -44654 3.8 SP1 RXRA ZNF512 SOX6 CTBP1 YY1 MEF2D JUND NCOR1 RCOR1 HDAC4 HDAC4-AS1 MGC16025 GC02M239271
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MGC16025 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the MGC16025 gene promoter:
  • c-Myc
  • E2F
  • E2F-1
  • HEN1
  • Max1
  • NF-1
  • NF-1/L
  • Nkx5-1
  • Roaz
  • XBP-1

Genomic Locations for MGC16025 Gene

Genomic Locations for MGC16025 Gene
chr2:239,193,331-239,195,457
(GRCh38/hg38)
Size:
2,127 bases
Orientation:
Minus strand
chr2:240,115,027-240,117,153
(GRCh37/hg19)
Size:
2,127 bases
Orientation:
Minus strand

Genomic View for MGC16025 Gene

Genes around MGC16025 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MGC16025 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MGC16025 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MGC16025 Gene

Proteins for MGC16025 Gene

  • Protein details for MGC16025 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Q53SB4-Q53SB4_HUMAN
    Recommended name:
    Uncharacterized protein MGC16025
    Protein Accession:
    Q53SB4

    Protein attributes for MGC16025 Gene

    Size:
    31 amino acids
    Molecular mass:
    3359 Da
    Quaternary structure:
    No Data Available
  • Protein details for MGC16025 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Q53SM2-Q53SM2_HUMAN
    Recommended name:
    Uncharacterized protein MGC16025
    Protein Accession:
    Q53SM2

    Protein attributes for MGC16025 Gene

    Size:
    1052 amino acids
    Molecular mass:
    115600 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MGC16025 Gene

Post-translational modifications for MGC16025 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MGC16025 Gene

Domains & Families for MGC16025 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MGC16025: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MGC16025 Gene

Function for MGC16025 Gene

Phenotypes From GWAS Catalog for MGC16025 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MGC16025 Gene

Localization for MGC16025 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MGC16025 Gene

Pathways & Interactions for MGC16025 Gene

genes like me logo Genes that share pathways with MGC16025: view

Interacting Proteins for MGC16025 Gene

Gene Ontology (GO) - Biological Process for MGC16025 Gene

None

No data available for SIGNOR curated interactions for MGC16025 Gene

Drugs & Compounds for MGC16025 Gene

No Compound Related Data Available

Transcripts for MGC16025 Gene

mRNA/cDNA for MGC16025 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) RNA Central transcripts :

Unigene Clusters for MGC16025 Gene

Uncharacterized LOC85009:
Representative Sequences:

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MGC16025 Gene

No ASD Table

Relevant External Links for MGC16025 Gene

GeneLoc Exon Structure for
MGC16025

Expression for MGC16025 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MGC16025 Gene

SOURCE GeneReport for Unigene cluster for MGC16025 Gene:

Hs.744565
genes like me logo Genes that share expression patterns with MGC16025: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MGC16025 Gene

Orthologs for MGC16025 Gene

No data available for Orthologs and Evolution for MGC16025 Gene

Paralogs for MGC16025 Gene

(6) SIMAP similar genes for MGC16025 Gene using alignment to 2 proteins:

  • Q53SB4_HUMAN
  • Q53SM2_HUMAN
genes like me logo Genes that share paralogs with MGC16025: view

No data available for Paralogs for MGC16025 Gene

Variants for MGC16025 Gene

Sequence variations from dbSNP and Humsavar for MGC16025 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000578689 -- 239,194,341(-) A/C/G non_coding_transcript_variant
rs1001007293 -- 239,193,465(-) G/A non_coding_transcript_variant
rs1001452365 -- 239,197,027(-) C/T upstream_transcript_variant
rs1001458947 -- 239,197,249(-) G/A upstream_transcript_variant
rs1002676797 -- 239,196,008(-) G/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MGC16025 Gene

Variant ID Type Subtype PubMed ID
dgv4195n100 CNV gain 25217958
nsv1010141 CNV loss 25217958
nsv834582 CNV loss 17160897

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Additional Variant Information for MGC16025 Gene

Disorders for MGC16025 Gene

Additional Disease Information for MGC16025

Genetic Association Database
(GAD)

No disorders were found for MGC16025 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MGC16025 Gene

Publications for MGC16025 Gene

  1. IRES-dependent translation of the long non coding RNA meloe in melanoma cells produces the most immunogenic MELOE antigens. (PMID: 27486971) Charpentier M … Lang F (Oncotarget 2016) 3 58
  2. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. (PMID: 23453885) Cross-Disorder Group of the Psychiatric Genomics Consortium (Lancet (London, England) 2013) 3 58
  3. The melanoma antigens MELOE-1 and MELOE-2 are translated from a bona fide polycistronic mRNA containing functional IRES sequences. (PMID: 24086473) Carbonnelle D … Lang F (PloS one 2013) 3 58
  4. Overexpression of meloe gene in melanomas is controlled both by specific transcription factors and hypomethylation. (PMID: 24086527) Bobinet M … Moreau-Aubry A (PloS one 2013) 3 58
  5. Frequent occurrence of high affinity T cells against MELOE-1 makes this antigen an attractive target for melanoma immunotherapy. (PMID: 20217862) Godet Y … Labarrière N (European journal of immunology 2010) 3 58

No data available for External Links for MGC16025 Gene

Products for MGC16025 Gene

Sources for MGC16025 Gene

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