Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MGAT4B Gene

Aliases for MGAT4B Gene

  • Mannosyl (Alpha-1,3-)-Glycoprotein Beta-1,4-N-Acetylglucosaminyltransferase, Isozyme B 2 3 5
  • UDP-N-Acetylglucosamine: Alpha-1,3-D-Mannoside Beta-1,4-N-Acetylglucosaminyltransferase IVb 3 4
  • Mannosyl (Alpha-1,3-)-Glycoprotein Beta-1,4-N-Acetylglucosaminyltransferase, Isoenzyme B 2 3
  • N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase IVb 3 4
  • N-Acetylglucosaminyltransferase IVb 3 4
  • GlcNAc-T IVb 3 4
  • UDP-N-Acetylglucosamine: Alpha-1,3-D-Mannoside Beta-1,4-N-Acetylglucosaminyltransferase IV 3
  • Alpha-1,3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase B 3
  • Alpha-1,3-Mannosyl-Glycoprotein Beta-1,4-N-Acetylglucosaminyltransferase 3
  • Aminyltransferase 3
  • EC 2.4.1.145 4
  • GNT-IVB 3
  • GnT-IVb 4
  • GNT-IV 3

External Ids for MGAT4B Gene

Previous GeneCards Identifiers for MGAT4B Gene

  • GC05M179336
  • GC05M180168
  • GC05M179334
  • GC05M179157
  • GC05M173950
  • GC05M179224

Summaries for MGAT4B Gene

Entrez Gene Summary for MGAT4B Gene

  • This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme A, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation. [provided by RefSeq, Jul 2008]

GeneCards Summary for MGAT4B Gene

MGAT4B (Mannosyl (Alpha-1,3-)-Glycoprotein Beta-1,4-N-Acetylglucosaminyltransferase, Isozyme B) is a Protein Coding gene. Among its related pathways are N-glycan antennae elongation in the medial/trans-Golgi and N-Glycan biosynthesis. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring hexosyl groups and alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity. An important paralog of this gene is MGAT4A.

UniProtKB/Swiss-Prot for MGAT4B Gene

  • Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis.

Gene Wiki entry for MGAT4B Gene

Additional gene information for MGAT4B Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MGAT4B Gene

Genomics for MGAT4B Gene

GeneHancer (GH) Regulatory Elements for MGAT4B Gene

Promoters and enhancers for MGAT4B Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05J179803 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 659.3 +1.0 1000 5.9 HDGF FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SP3 SP5 MGAT4B SQSTM1 ZNF879 LOC100996419 ZFP2 ZNF454 GRM6 ENSG00000254035 ZNF354C MRNIP
GH05J179696 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 16.6 +108.0 108007 4.9 CLOCK FEZF1 DMAP1 IRF4 YY1 SLC30A9 E2F8 ZNF143 SP3 NFYC CANX GC05M179696 MAML1 HNRNPH1 ZNF354B RUFY1 MRNIP CNOT6 ZNF879 LOC101928445
GH05J179764 Enhancer 1.2 Ensembl ENCODE dbSUPER 18.1 +41.1 41070 2.2 HDAC1 YY1 TCF12 FOS RXRA REST ZEB2 ZNF592 SP1 SMARCA4 MAML1 MGAT4B LTC4S MIR1229 SQSTM1 CBY3 MRNIP TBC1D9B CANX RNF130
GH05J179761 Enhancer 1.3 Ensembl ENCODE dbSUPER 13.5 +43.9 43917 2.9 HDGF PKNOX1 CLOCK ARID4B SIN3A ZNF2 GLIS2 GATA2 ZNF143 FOS MRNIP MAML1 ZNF879 LOC100996419 LTC4S MIR1229 SQSTM1 MGAT4B ZFP2 ZNF454
GH05J179793 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 8.1 +11.7 11650 4.5 HDGF ARID4B SIN3A GLI4 ZNF2 ZNF48 ZNF121 GLIS2 ELK1 ZNF207 LTC4S MRNIP ZNF879 ZFP2 LOC100996419 ZNF354C RN7SKP150 ENSG00000254035 ZNF454 GRM6
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MGAT4B on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the MGAT4B gene promoter:
  • Sp1
  • NF-kappaB1

Genomic Locations for MGAT4B Gene

Genomic Locations for MGAT4B Gene
chr5:179,797,597-179,806,952
(GRCh38/hg38)
Size:
9,356 bases
Orientation:
Minus strand
chr5:179,224,597-179,233,952
(GRCh37/hg19)
Size:
9,356 bases
Orientation:
Minus strand

Genomic View for MGAT4B Gene

Genes around MGAT4B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MGAT4B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MGAT4B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MGAT4B Gene

Proteins for MGAT4B Gene

  • Protein details for MGAT4B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UQ53-MGT4B_HUMAN
    Recommended name:
    Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
    Protein Accession:
    Q9UQ53
    Secondary Accessions:
    • A8MPR0
    • Q86TF1
    • Q96GH4
    • Q9NSK6

    Protein attributes for MGAT4B Gene

    Size:
    548 amino acids
    Molecular mass:
    63198 Da
    Cofactor:
    Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MGAT4B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MGAT4B Gene

Post-translational modifications for MGAT4B Gene

  • Glycosylation at isoforms=2, 3490, isoforms=2, 3103, and isoforms=2, 387
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for MGAT4B Gene

Domains & Families for MGAT4B Gene

Gene Families for MGAT4B Gene

HGNC:
Human Protein Atlas (HPA):
  • Enzymes
  • Predicted intracellular proteins
  • Predicted secreted proteins

Protein Domains for MGAT4B Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q9UQ53

UniProtKB/Swiss-Prot:

MGT4B_HUMAN :
  • Belongs to the glycosyltransferase 54 family.
Family:
  • Belongs to the glycosyltransferase 54 family.
genes like me logo Genes that share domains with MGAT4B: view

Function for MGAT4B Gene

Molecular function for MGAT4B Gene

UniProtKB/Swiss-Prot Function:
Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis.
UniProtKB/Swiss-Prot CatalyticActivity:
UDP-N-acetyl-alpha-D-glucosamine + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-(beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein] = UDP + beta-D-GlcNAc-(1->2)-(beta-D-GlcNAc-(1->4))-alpha-D-Man-(1->3)-(beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein].
UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=0.242 mM for UDP-GlcNAc {ECO:0000269 PubMed:17006639};
GENATLAS Biochemistry:
mannosyl (alpha-1,3-)glycoprotein beta,4-N acetylglucosaminyltransferase,isoenzyme B

Enzyme Numbers (IUBMB) for MGAT4B Gene

Phenotypes From GWAS Catalog for MGAT4B Gene

Gene Ontology (GO) - Molecular Function for MGAT4B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008375 acetylglucosaminyltransferase activity IEA --
GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity TAS --
GO:0016740 transferase activity IEA --
GO:0016757 transferase activity, transferring glycosyl groups IEA --
GO:0016758 transferase activity, transferring hexosyl groups IEA --
genes like me logo Genes that share ontologies with MGAT4B: view
genes like me logo Genes that share phenotypes with MGAT4B: view

Animal Models for MGAT4B Gene

MGI Knock Outs for MGAT4B:

Animal Model Products

  • Taconic Biosciences Mouse Models for MGAT4B

miRNA for MGAT4B Gene

miRTarBase miRNAs that target MGAT4B

Clone Products

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MGAT4B Gene

Localization for MGAT4B Gene

Subcellular locations from UniProtKB/Swiss-Prot for MGAT4B Gene

Golgi apparatus membrane; Single-pass type II membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MGAT4B gene
Compartment Confidence
golgi apparatus 5
mitochondrion 2
cytosol 2
nucleus 1
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for MGAT4B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane TAS --
GO:0005794 Golgi apparatus IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with MGAT4B: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for MGAT4B Gene

Pathways & Interactions for MGAT4B Gene

genes like me logo Genes that share pathways with MGAT4B: view

UniProtKB/Swiss-Prot Q9UQ53-MGT4B_HUMAN

  • Pathway: Protein modification; protein glycosylation.

Gene Ontology (GO) - Biological Process for MGAT4B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005975 carbohydrate metabolic process IEA --
GO:0006486 protein glycosylation IEA --
GO:0006487 protein N-linked glycosylation IEA --
GO:0006491 N-glycan processing TAS 10372966
genes like me logo Genes that share ontologies with MGAT4B: view

No data available for SIGNOR curated interactions for MGAT4B Gene

Drugs & Compounds for MGAT4B Gene

(1) Drugs for MGAT4B Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Uridine 5'-diphosphate Experimental Pharma 0

(1) Additional Compounds for MGAT4B Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Uridine diphosphate-N-acetylglucosamine
  • (2R,3R,4R,5S,6R)-3-(acetylamino)-4,5-Dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name)
  • UDP-GlcNAc
  • UDP-N-Acetyl-D-glucosamine
  • UDP-N-Acetylglucosamine
  • URIDINE-diphosphATE-N-acetylglucosamine
528-04-1
genes like me logo Genes that share compounds with MGAT4B: view

Transcripts for MGAT4B Gene

mRNA/cDNA for MGAT4B Gene

(5) REFSEQ mRNAs :
(9) Additional mRNA sequences :
(13) Selected AceView cDNA sequences:
(23) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MGAT4B Gene

Mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MGAT4B Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b · 5c ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b · 12c ^ 13a · 13b ·
SP1: - - - - - - - - -
SP2: -
SP3:
SP4: - - - - - - -
SP5:
SP6:
SP7: - -
SP8: - - -
SP9:
SP10: - - - - - - - - - - -
SP11:
SP12: - -
SP13: - - - -
SP14:
SP15: - - -
SP16:
SP17: - - - - -
SP18:
SP19: -
SP20:

ExUns: 13c · 13d ^ 14a · 14b ^ 15a · 15b ^ 16a · 16b · 16c · 16d ^ 17 ^ 18a · 18b ^ 19a · 19b · 19c · 19d
SP1: - - - -
SP2: - - - -
SP3: - - - - -
SP4:
SP5: - -
SP6: - - -
SP7: - - - - - - -
SP8:
SP9: - - -
SP10:
SP11: - - -
SP12:
SP13:
SP14: - -
SP15: - -
SP16: - -
SP17:
SP18: -
SP19:
SP20:

Relevant External Links for MGAT4B Gene

GeneLoc Exon Structure for
MGAT4B
ECgene alternative splicing isoforms for
MGAT4B

Expression for MGAT4B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MGAT4B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MGAT4B Gene

This gene is overexpressed in Liver (x4.3).

Protein differential expression in normal tissues from HIPED for MGAT4B Gene

This gene is overexpressed in Plasma (25.2), Heart (21.4), and Bone (18.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MGAT4B Gene



Protein tissue co-expression partners for MGAT4B Gene

NURSA nuclear receptor signaling pathways regulating expression of MGAT4B Gene:

MGAT4B

SOURCE GeneReport for Unigene cluster for MGAT4B Gene:

Hs.567419

mRNA Expression by UniProt/SwissProt for MGAT4B Gene:

Q9UQ53-MGT4B_HUMAN
Tissue specificity: Widely expressed. Strongly overexpressed in pancreatic cancer.

Evidence on tissue expression from TISSUES for MGAT4B Gene

  • Lung(4.9)
  • Nervous system(4.9)
  • Pancreas(4.5)
  • Skin(4.3)
  • Intestine(4)
  • Eye(3.9)
  • Kidney(3.6)
  • Liver(2)
genes like me logo Genes that share expression patterns with MGAT4B: view

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for MGAT4B Gene

Orthologs for MGAT4B Gene

This gene was present in the common ancestor of animals.

Orthologs for MGAT4B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MGAT4B 34 33
  • 99.33 (n)
OneToOne
dog
(Canis familiaris)
Mammalia MGAT4B 34 33
  • 92.94 (n)
OneToOne
cow
(Bos Taurus)
Mammalia MGAT4B 34 33
  • 91.69 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mgat4b 33
  • 90.57 (n)
mouse
(Mus musculus)
Mammalia Mgat4b 16 34 33
  • 90.51 (n)
oppossum
(Monodelphis domestica)
Mammalia MGAT4B 34
  • 88 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MGAT4B 34
  • 83 (a)
OneToOne
chicken
(Gallus gallus)
Aves MGAT4B 34 33
  • 81.78 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MGAT4B 34
  • 82 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100489322 33
  • 76.8 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.4569 33
zebrafish
(Danio rerio)
Actinopterygii mgat4b 34 33
  • 74.79 (n)
OneToOne
wufb01d02 33
fruit fly
(Drosophila melanogaster)
Insecta CG9384 34 35
  • 37 (a)
OneToMany
CG17173 35
  • 37 (a)
Species where no ortholog for MGAT4B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MGAT4B Gene

ENSEMBL:
Gene Tree for MGAT4B (if available)
TreeFam:
Gene Tree for MGAT4B (if available)
Aminode:
Evolutionary constrained regions (ECRs) for MGAT4B: view image

Paralogs for MGAT4B Gene

Paralogs for MGAT4B Gene

(3) SIMAP similar genes for MGAT4B Gene using alignment to 10 proteins:

  • MGT4B_HUMAN
  • E5RFL0_HUMAN
  • E5RFS3_HUMAN
  • H0YB63_HUMAN
  • H0YB84_HUMAN
  • H0YB89_HUMAN
  • H0YC11_HUMAN
  • H0YC13_HUMAN
  • H0YC56_HUMAN
  • H0YC79_HUMAN
genes like me logo Genes that share paralogs with MGAT4B: view

Variants for MGAT4B Gene

Sequence variations from dbSNP and Humsavar for MGAT4B Gene

SNP ID Clin Chr 05 pos Variation AA Info Type
rs1000000759 -- 179,798,720(-) C/A/T intron_variant
rs1000170620 -- 179,808,339(-) GGG/GG upstream_transcript_variant
rs1000365167 -- 179,808,583(-) C/T upstream_transcript_variant
rs1000610493 -- 179,802,194(-) C/T 5_prime_UTR_variant, intron_variant
rs1000699365 -- 179,807,616(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MGAT4B Gene

Variant ID Type Subtype PubMed ID
dgv10240n54 CNV loss 21841781
dgv10241n54 CNV loss 21841781
esv3570596 CNV loss 25503493
esv988291 CNV deletion 20482838
nsv1133621 CNV deletion 24896259
nsv469579 CNV loss 16826518
nsv518964 CNV loss 19592680
nsv600659 CNV loss 21841781
nsv600660 CNV loss 21841781
nsv600661 CNV loss 21841781
nsv600668 CNV loss 21841781
nsv823361 CNV loss 20364138

Variation tolerance for MGAT4B Gene

Residual Variation Intolerance Score: 68.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.22; 52.32% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MGAT4B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MGAT4B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MGAT4B Gene

Disorders for MGAT4B Gene

Additional Disease Information for MGAT4B

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MGAT4B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MGAT4B Gene

Publications for MGAT4B Gene

  1. Kinetic properties and substrate specificities of two recombinant human N-acetylglucosaminyltransferase-IV isozymes. (PMID: 17006639) Oguri S … Takeuchi M (Glycoconjugate journal 2006) 3 4 22 58
  2. A novel second isoenzyme of the human UDP-N-acetylglucosamine:alpha1,3-D-mannoside beta1,4-N-acetylglucosaminyltransferase family: cDNA cloning, expression, and chromosomal assignment. (PMID: 10372966) Yoshida A … Takeuchi M (Glycoconjugate journal 1998) 2 3 4 58
  3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 44 58
  4. N-glycan alterations are associated with drug resistance in human hepatocellular carcinoma. (PMID: 17488527) Kudo T … Todo S (Molecular cancer 2007) 3 22 58
  5. Aberrant expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer. (PMID: 16434023) Ide Y … Taniguchi N (Biochemical and biophysical research communications 2006) 3 4 58

Products for MGAT4B Gene

Sources for MGAT4B Gene

Content
Loading form....