This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme B, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-M... See more...

Aliases for MGAT4A Gene

Aliases for MGAT4A Gene

  • Alpha-1,3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase A 2 3 4 5
  • UDP-N-Acetylglucosamine: Alpha-1,3-D-Mannoside Beta-1,4-N-Acetylglucosaminyltransferase IVa 3 4
  • Mannosyl (Alpha-1,3-)-Glycoprotein Beta-1,4-N-Acetylglucosaminyltransferase, Isoenzyme A 2 3
  • Mannosyl (Alpha-1,3-)-Glycoprotein Beta-1,4-N-Acetylglucosaminyltransferase, Isozyme A 2 3
  • N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase IVa 3 4
  • N-Acetylglucosaminyltransferase IVa 3 4
  • GlcNAc-T IVa 3 4
  • EC 2.4.1.145 4 51
  • GnT-4a 2 3
  • UDP-N-Acetylglucosamine:Alpha1,3-D-Mannoside Beta1,4-N-Acetylglucosaminyltransferase 3
  • Alpha-1,3-Mannosyl-Glycoprotein Beta-1,4-N-Acetylglucosaminyltransferase 3
  • UDP-GlcNAc:A-1,3-D-Mannoside B-1,4-Acetylglucosaminyltransferase IV 3
  • GNT-IVA 3
  • GnT-Iva 2
  • GnT-IVa 4
  • GNT-IV 3
  • MGAT4A 5

External Ids for MGAT4A Gene

Previous GeneCards Identifiers for MGAT4A Gene

  • GC02M097123
  • GC02M097694
  • GC02M098842
  • GC02M098863
  • GC02M098700
  • GC02M099236
  • GC02M093000

Summaries for MGAT4A Gene

Entrez Gene Summary for MGAT4A Gene

  • This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme B, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation. [provided by RefSeq, Jul 2008]

GeneCards Summary for MGAT4A Gene

MGAT4A (Alpha-1,3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase A) is a Protein Coding gene. Diseases associated with MGAT4A include Choriocarcinoma and Congenital Disorder Of Glycosylation, Type Iia. Among its related pathways are Transport to the Golgi and subsequent modification and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring hexosyl groups and alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity. An important paralog of this gene is MGAT4B.

UniProtKB/Swiss-Prot Summary for MGAT4A Gene

  • Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells.

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MGAT4A Gene

Genomics for MGAT4A Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MGAT4A Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MGAT4A on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MGAT4A

Top Transcription factor binding sites by QIAGEN in the MGAT4A gene promoter:
  • aMEF-2
  • c-Ets-1
  • C/EBPbeta
  • FAC1
  • HNF-1
  • HNF-1A
  • MEF-2
  • MEF-2A
  • Pax-5
  • RP58

Genomic Locations for MGAT4A Gene

Genomic Locations for MGAT4A Gene
chr2:98,619,106-98,731,132
(GRCh38/hg38)
Size:
112,027 bases
Orientation:
Minus strand
chr2:99,235,569-99,347,589
(GRCh37/hg19)
Size:
112,021 bases
Orientation:
Minus strand

Genomic View for MGAT4A Gene

Genes around MGAT4A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MGAT4A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MGAT4A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MGAT4A Gene

Proteins for MGAT4A Gene

  • Protein details for MGAT4A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UM21-MGT4A_HUMAN
    Recommended name:
    Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
    Protein Accession:
    Q9UM21
    Secondary Accessions:
    • B4E2R6
    • D3DVH6
    • E9PEN2
    • Q53S97
    • Q86Z15

    Protein attributes for MGAT4A Gene

    Size:
    535 amino acids
    Molecular mass:
    61544 Da
    Cofactor:
    Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MGAT4A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MGAT4A Gene

Selected DME Specific Peptides for MGAT4A Gene

Q9UM21:
  • VVANLEKEF
  • PEEKLDCV
  • TIKNFALQL
  • KPIDWLLDHI
  • ILNEIHIK
  • AEHRISQRSSELNTIVQQF
  • IVQQFKRV
  • GKIQKLTDKD
  • WMILEFSQLGFIGKMF
  • MFYKEKPIDWLL
  • FRPSLFQHVGLHSSL
  • LNPISAFRLSV
  • ETLHSLID
  • YYIQLEDDI
  • SKETKDKRLEDGYFRIGKFENGVAEG
  • KERVRWRTKQNLDYCFLMMYAQ
  • NTTVEVLP
  • VMGIPTVKR
  • AGDYILFKFDKPVN
  • DCVIVVFI
  • VFIGETD
  • HVNPPAEVSTSLK
  • ALKERLRIAEHR
  • NKFSDNT
  • YLFHSGN

Post-translational modifications for MGAT4A Gene

  • Glycosylation at Ser59, Ser60, Thr64, Asn77, Thr376, and Asn458
  • Modification sites at PhosphoSitePlus

Other Protein References for MGAT4A Gene

Domains & Families for MGAT4A Gene

Gene Families for MGAT4A Gene

HGNC:
Human Protein Atlas (HPA):
  • Enzymes
  • Predicted intracellular proteins
  • Predicted secreted proteins

Protein Domains for MGAT4A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for MGAT4A Gene

GenScript: Design optimal peptide antigens:
  • UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVa (MGT4A_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9UM21

UniProtKB/Swiss-Prot:

MGT4A_HUMAN :
  • Belongs to the glycosyltransferase 54 family.
Family:
  • Belongs to the glycosyltransferase 54 family.
genes like me logo Genes that share domains with MGAT4A: view

Function for MGAT4A Gene

Molecular function for MGAT4A Gene

UniProtKB/Swiss-Prot Function:
Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = H(+) + N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAcl-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP; Xref=Rhea:RHEA:16057, Rhea:RHEA-COMP:13526, Rhea:RHEA-COMP:14374, ChEBI:CHEBI:15378, ChEBI:CHEBI:57705, ChEBI:CHEBI:58223, ChEBI:CHEBI:60651, ChEBI:CHEBI:139507; EC=2.4.1.145;.
UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=0.118 mM for UDP-GlcNAc {ECO:0000269|PubMed:17006639};
GENATLAS Biochemistry:
mannosyl (alpha-1,3-)glycoprotein beta,4-N acetylglucosaminyltransferase,isoenzyme A

Enzyme Numbers (IUBMB) for MGAT4A Gene

Phenotypes From GWAS Catalog for MGAT4A Gene

Gene Ontology (GO) - Molecular Function for MGAT4A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008375 acetylglucosaminyltransferase activity IBA 21873635
GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity TAS,IEA --
GO:0016740 transferase activity IEA --
GO:0016757 transferase activity, transferring glycosyl groups IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with MGAT4A: view
genes like me logo Genes that share phenotypes with MGAT4A: view

Animal Models for MGAT4A Gene

MGI Knock Outs for MGAT4A:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MGAT4A

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MGAT4A Gene

Localization for MGAT4A Gene

Subcellular locations from UniProtKB/Swiss-Prot for MGAT4A Gene

[Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A]: Golgi apparatus membrane. Single-pass type II membrane protein.
[Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A soluble form]: Secreted.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MGAT4A gene
Compartment Confidence
extracellular 4
endoplasmic reticulum 4
golgi apparatus 4
mitochondrion 2
cytosol 2
plasma membrane 1
cytoskeleton 1
nucleus 1
endosome 1
lysosome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Golgi apparatus (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for MGAT4A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane TAS --
GO:0005576 extracellular region IEA --
GO:0005783 endoplasmic reticulum IBA 21873635
GO:0005788 endoplasmic reticulum lumen TAS --
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment IBA 21873635
genes like me logo Genes that share ontologies with MGAT4A: view

Pathways & Interactions for MGAT4A Gene

genes like me logo Genes that share pathways with MGAT4A: view

UniProtKB/Swiss-Prot Q9UM21-MGT4A_HUMAN

  • Pathway: Protein modification; protein glycosylation.

Gene Ontology (GO) - Biological Process for MGAT4A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006486 protein glycosylation IEA --
GO:0006487 protein N-linked glycosylation IBA 21873635
GO:0006491 N-glycan processing TAS 10024668
GO:0043687 post-translational protein modification TAS --
GO:0044267 cellular protein metabolic process TAS --
genes like me logo Genes that share ontologies with MGAT4A: view

No data available for SIGNOR curated interactions for MGAT4A Gene

Drugs & Compounds for MGAT4A Gene

(5) Drugs for MGAT4A Gene - From: PharmGKB and HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Bevacizumab Approved, Investigational Pharma VEGF antagonist, Therapeutic Antibodies, Vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) inhibitors 2368
Capecitabine Approved, Investigational Pharma RNA processing inhibitor and thymidylate synthase inhibitor, F-pyrimidines 1669
Cetuximab Approved Pharma EGFR Inhibitors, Therapeutic Antibodies, Epidermal growth factor receptor (EGFR) inhibitors 869
Oxaliplatin Approved, Investigational Pharma Antitumor agent, Platinum 1944
Uridine 5'-diphosphate Experimental Pharma 0

(2) Additional Compounds for MGAT4A Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Uridine diphosphate-N-acetylglucosamine
  • (2R,3R,4R,5S,6R)-3-(acetylamino)-4,5-Dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name)
  • UDP-GlcNAc
  • UDP-N-Acetyl-D-glucosamine
  • UDP-N-Acetylglucosamine
  • URIDINE-diphosphATE-N-acetylglucosamine
528-04-1
genes like me logo Genes that share compounds with MGAT4A: view

Transcripts for MGAT4A Gene

mRNA/cDNA for MGAT4A Gene

2 REFSEQ mRNAs :
10 NCBI additional mRNA sequence :
9 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MGAT4A

Alternative Splicing Database (ASD) splice patterns (SP) for MGAT4A Gene

No ASD Table

Relevant External Links for MGAT4A Gene

GeneLoc Exon Structure for
MGAT4A

Expression for MGAT4A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MGAT4A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for MGAT4A Gene

This gene is overexpressed in Liver (26.3), Placenta (18.2), CD8 Tcells (15.6), and Pancreas (9.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MGAT4A Gene



Protein tissue co-expression partners for MGAT4A Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MGAT4A

SOURCE GeneReport for Unigene cluster for MGAT4A Gene:

Hs.177576

mRNA Expression by UniProt/SwissProt for MGAT4A Gene:

Q9UM21-MGT4A_HUMAN
Tissue specificity: Expressed in pancreas, spleen, thymus, prostate, small intestine, peripheral blood leukocytes and lymph node. Strongly overexpressed in choriocarcinoma cancer cell lines. Down-regulated in pancreatic cancer.

Evidence on tissue expression from TISSUES for MGAT4A Gene

  • Liver(4.3)
  • Nervous system(2.7)
  • Pancreas(2.3)
  • Kidney(2)
genes like me logo Genes that share expression patterns with MGAT4A: view

No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for MGAT4A Gene

Orthologs for MGAT4A Gene

This gene was present in the common ancestor of animals.

Orthologs for MGAT4A Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia MGAT4A 30 31
  • 99.69 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia MGAT4A 30 31
  • 93.4 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia MGAT4A 30 31
  • 91.03 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Mgat4a 30
  • 86.54 (n)
Mouse
(Mus musculus)
Mammalia Mgat4a 30 17 31
  • 85.98 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia MGAT4A 31
  • 84 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia MGAT4A 31
  • 66 (a)
OneToOne
Chicken
(Gallus gallus)
Aves MGAT4A 30 31
  • 81.68 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia MGAT4A 31
  • 87 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia mgat4b 30
  • 77.01 (n)
Zebrafish
(Danio rerio)
Actinopterygii mgat4a 30 31
  • 70.94 (n)
OneToOne
Fruit Fly
(Drosophila melanogaster)
Insecta CG17173 32
  • 37 (a)
CG9384 31 32
  • 36 (a)
OneToMany
Species where no ortholog for MGAT4A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for MGAT4A Gene

ENSEMBL:
Gene Tree for MGAT4A (if available)
TreeFam:
Gene Tree for MGAT4A (if available)
Aminode:
Evolutionary constrained regions (ECRs) for MGAT4A: view image

Paralogs for MGAT4A Gene

Paralogs for MGAT4A Gene

(3) SIMAP similar genes for MGAT4A Gene using alignment to 2 proteins:

  • MGT4A_HUMAN
  • U3KPT4_HUMAN
genes like me logo Genes that share paralogs with MGAT4A: view

Variants for MGAT4A Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MGAT4A Gene

SNP ID Clinical significance and condition Chr 02 pos Variation AA Info Type
710312 Benign: not provided 98,655,513(-) T/C MISSENSE_VARIANT
718738 Benign: not provided 98,639,948(-) C/T SYNONYMOUS_VARIANT

Additional dbSNP identifiers (rs#s) for MGAT4A Gene

Structural Variations from Database of Genomic Variants (DGV) for MGAT4A Gene

Variant ID Type Subtype PubMed ID
esv2450775 CNV insertion 19546169
esv3413045 CNV insertion 20981092
esv988416 CNV insertion 20482838
nsv1072956 CNV deletion 25765185
nsv1144907 CNV deletion 24896259
nsv2841 CNV deletion 18451855
nsv582516 CNV loss 21841781
nsv953493 CNV duplication 24416366

Variation tolerance for MGAT4A Gene

Residual Variation Intolerance Score: 50.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.65; 45.69% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MGAT4A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MGAT4A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MGAT4A Gene

Disorders for MGAT4A Gene

MalaCards: The human disease database

(2) MalaCards diseases for MGAT4A Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
choriocarcinoma
  • chorioepithelioma
congenital disorder of glycosylation, type iia
  • cdg2a
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MGAT4A

genes like me logo Genes that share disorders with MGAT4A: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MGAT4A Gene

Publications for MGAT4A Gene

  1. Aberrant expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer. (PMID: 16434023) Ide Y … Taniguchi N (Biochemical and biophysical research communications 2006) 3 4 23
  2. Kinetic properties and substrate specificities of two recombinant human N-acetylglucosaminyltransferase-IV isozymes. (PMID: 17006639) Oguri S … Takeuchi M (Glycoconjugate journal 2006) 3 4 23
  3. Tissue specific expression and chromosomal mapping of a human UDP-N-acetylglucosamine: alpha1,3-d-mannoside beta1, 4-N-acetylglucosaminyltransferase. (PMID: 10024668) Yoshida A … Takeuchi M (Glycobiology 1999) 2 3 4
  4. Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes. (PMID: 21738484) Smith EN … Kelsoe JR (PLoS genetics 2011) 3 41
  5. N-glycan alterations are associated with drug resistance in human hepatocellular carcinoma. (PMID: 17488527) Kudo T … Todo S (Molecular cancer 2007) 3 23

Products for MGAT4A Gene

  • Signalway ELISA kits for MGAT4A

Sources for MGAT4A Gene