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Aliases for MGAT3 Gene

Aliases for MGAT3 Gene

  • Mannosyl (Beta-1,4-)-Glycoprotein Beta-1,4-N-Acetylglucosaminyltransferase 2 3 5
  • N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase III 3 4
  • Beta-1,4-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase 3 4
  • N-Acetylglucosaminyltransferase III 3 4
  • GlcNAc-T III 3 4
  • GNT-III 3 4
  • EC 2.4.1.144 4
  • GGNT3 4
  • GNT3 3

External Ids for MGAT3 Gene

Previous GeneCards Identifiers for MGAT3 Gene

  • GC22P036467
  • GC22P038096
  • GC22P038177
  • GC22P038183
  • GC22P039853
  • GC22P022847

Summaries for MGAT3 Gene

Entrez Gene Summary for MGAT3 Gene

  • There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. The enzyme encoded by this gene transfers a GlcNAc residue to the beta-linked mannose of the trimannosyl core of N-linked oligosaccharides and produces a bisecting GlcNAc. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

GeneCards Summary for MGAT3 Gene

MGAT3 (Mannosyl (Beta-1,4-)-Glycoprotein Beta-1,4-N-Acetylglucosaminyltransferase) is a Protein Coding gene. Among its related pathways are Transport to the Golgi and subsequent modification and N-glycan antennae elongation in the medial/trans-Golgi. Gene Ontology (GO) annotations related to this gene include beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity.

UniProtKB/Swiss-Prot for MGAT3 Gene

  • It is involved in the regulation of the biosynthesis and biological function of glycoprotein oligosaccharides. Catalyzes the addition of N-acetylglucosamine in beta 1-4 linkage to the beta-linked mannose of the trimannosyl core of N-linked sugar chains, called bisecting N-acetylglucosamine (GlcNAc). It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. The addition of this bisecting GlcNAc residue alters not only the composition, but also the conformation of the N-glycan. The introduction of the bisecting GlcNAc residue results in the suppression of further processing and elongation of N-glycans, precluding the formation of beta-1,6 GlcNAc branching, catalyzed by MGAT5 since it is unable to use the bisected oligosaccharide as a substrate (PubMed:19403558). Addition of bisecting N-acetylglucosamine to CDH1/E-cadherin modulates CDH1 cell membrane location (PubMed:19403558). Inhibits NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc- formation which modulates sialylation levels and plays a role in cell migration regulation (PubMed:26801611). In brain, addition of bisecting N-acetylglucosamine to BACE1 blocks its lysosomal targeting in response to oxidative stress and further degradation which increases its location to early endosome and the APP cleavage (By similarity).

Gene Wiki entry for MGAT3 Gene

Additional gene information for MGAT3 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MGAT3 Gene

Genomics for MGAT3 Gene

GeneHancer (GH) Regulatory Elements for MGAT3 Gene

Promoters and enhancers for MGAT3 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J039462 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 627.1 +22.1 22091 14.4 CTCF CBFA2T2 ZNF148 ZNF121 ZNF687 TRIM24 SP7 RELA SP1 PPARG MGAT3 SYNGR1 ENSG00000230912 MIEF1 RPS19BP1 TAB1 MGAT3-AS1 DDX17
GH22J039457 Promoter/Enhancer 2.2 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 604.2 +10.6 10619 2 ZNF148 NKRF MLLT1 EGR1 IKZF1 ZNF600 BACH1 ZIC2 LARP7 POLR2A MGAT3 SYNGR1 CBX7 MGAT3-AS1
GH22J039445 Promoter/Enhancer 1.8 EPDnew FANTOM5 ENCODE dbSUPER 600.7 -0.1 -51 4.1 SP1 NKRF POLR2A ZNF687 CREM PRDM1 MLLT1 IKZF1 BACH1 IKZF2 MGAT3 SYNGR1 LOC100506472
GH22J039452 Promoter/Enhancer 1.6 EPDnew ENCODE dbSUPER 600.4 +6.7 6694 2.8 CC2D1A CBFA2T2 ZNF121 TRIM24 ZNF639 SMARCA4 MTA1 CAVIN1 GMEB1 PKNOX1 MGAT3 SYNGR1 MGAT3-AS1 MIEF1
GH22J039500 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 20 +55.3 55253 3.8 SP1 ZFX ELF3 MNT ZNF148 NKRF POLR2A ZNF687 AHR ZNF24 GC22P039507 LOC105373035 GC22P039510 GC22P039509 GC22P039506 GC22P039505 GC22P039503 GC22P039502 MIEF1 ENSG00000285025
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MGAT3 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the MGAT3 gene promoter:
  • AP-1
  • ATF-2
  • c-Jun
  • HEN1
  • MAZR
  • Nkx2-5
  • PPAR-alpha
  • PPAR-gamma1
  • PPAR-gamma2
  • Spz1

Genomic Locations for MGAT3 Gene

Genomic Locations for MGAT3 Gene
chr22:39,447,182-39,492,194
(GRCh38/hg38)
Size:
45,013 bases
Orientation:
Plus strand
chr22:39,853,325-39,888,199
(GRCh37/hg19)
Size:
34,875 bases
Orientation:
Plus strand

Genomic View for MGAT3 Gene

Genes around MGAT3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MGAT3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MGAT3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MGAT3 Gene

Proteins for MGAT3 Gene

  • Protein details for MGAT3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q09327-MGAT3_HUMAN
    Recommended name:
    Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
    Protein Accession:
    Q09327
    Secondary Accessions:
    • A6NGD0
    • Q14CK5
    • Q6IC49
    • Q9UH32

    Protein attributes for MGAT3 Gene

    Size:
    533 amino acids
    Molecular mass:
    61313 Da
    Quaternary structure:
    • Interacts with MGAT4D.
    SequenceCaution:
    • Sequence=BAA02937.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for MGAT3 Gene

Post-translational modifications for MGAT3 Gene

  • Glycosylation at isoforms=141, isoforms=259, posLast=397397, and isoforms=241
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for MGAT3 Gene

Domains & Families for MGAT3 Gene

Gene Families for MGAT3 Gene

HGNC:
Human Protein Atlas (HPA):
  • Enzymes
  • Predicted intracellular proteins
  • Predicted secreted proteins

Protein Domains for MGAT3 Gene

Suggested Antigen Peptide Sequences for MGAT3 Gene

GenScript: Design optimal peptide antigens:
  • N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III (MGAT3_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q09327

UniProtKB/Swiss-Prot:

MGAT3_HUMAN :
  • Belongs to the glycosyltransferase 17 family.
Family:
  • Belongs to the glycosyltransferase 17 family.
genes like me logo Genes that share domains with MGAT3: view

Function for MGAT3 Gene

Molecular function for MGAT3 Gene

UniProtKB/Swiss-Prot Function:
It is involved in the regulation of the biosynthesis and biological function of glycoprotein oligosaccharides. Catalyzes the addition of N-acetylglucosamine in beta 1-4 linkage to the beta-linked mannose of the trimannosyl core of N-linked sugar chains, called bisecting N-acetylglucosamine (GlcNAc). It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. The addition of this bisecting GlcNAc residue alters not only the composition, but also the conformation of the N-glycan. The introduction of the bisecting GlcNAc residue results in the suppression of further processing and elongation of N-glycans, precluding the formation of beta-1,6 GlcNAc branching, catalyzed by MGAT5 since it is unable to use the bisected oligosaccharide as a substrate (PubMed:19403558). Addition of bisecting N-acetylglucosamine to CDH1/E-cadherin modulates CDH1 cell membrane location (PubMed:19403558). Inhibits NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc- formation which modulates sialylation levels and plays a role in cell migration regulation (PubMed:26801611). In brain, addition of bisecting N-acetylglucosamine to BACE1 blocks its lysosomal targeting in response to oxidative stress and further degradation which increases its location to early endosome and the APP cleavage (By similarity).
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = H(+) + N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->4)]-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP; Xref=Rhea:RHEA:15509, Rhea:RHEA-COMP:13526, Rhea:RHEA-COMP:14371, ChEBI:CHEBI:15378, ChEBI:CHEBI:57705, ChEBI:CHEBI:58223, ChEBI:CHEBI:60651, ChEBI:CHEBI:139504; EC=2.4.1.144; Evidence=. ;.
UniProtKB/Swiss-Prot Induction:
Expression is up-regulated by CDH1/E-cadherin-mediated cell-cell interaction.
GENATLAS Biochemistry:
mannosyl (beta-1,4-) glycoprotein beta-1,4-N-acetylglucosaminyltransferase,Golgi,biosynthesis of complex Asn-linked (N) glycans

Enzyme Numbers (IUBMB) for MGAT3 Gene

Phenotypes From GWAS Catalog for MGAT3 Gene

Gene Ontology (GO) - Molecular Function for MGAT3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003830 beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity TAS --
GO:0016740 transferase activity IEA --
GO:0016757 transferase activity, transferring glycosyl groups IBA 21873635
genes like me logo Genes that share ontologies with MGAT3: view
genes like me logo Genes that share phenotypes with MGAT3: view

Animal Models for MGAT3 Gene

MGI Knock Outs for MGAT3:

Animal Model Products

CRISPR Products

miRNA for MGAT3 Gene

miRTarBase miRNAs that target MGAT3

Clone Products

  • Applied Biological Materials (abm): Clones for MGAT3 - Now 50% OFF >
  • * MGAT3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * MGAT3 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
  • Addgene plasmids for MGAT3

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MGAT3 Gene

Localization for MGAT3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MGAT3 Gene

Golgi apparatus membrane; Single-pass type II membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MGAT3 gene
Compartment Confidence
golgi apparatus 4
extracellular 1
endosome 1
lysosome 1
peroxisome 0

Gene Ontology (GO) - Cellular Components for MGAT3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane TAS --
GO:0005794 Golgi apparatus IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with MGAT3: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for MGAT3 Gene

Pathways & Interactions for MGAT3 Gene

genes like me logo Genes that share pathways with MGAT3: view

UniProtKB/Swiss-Prot Q09327-MGAT3_HUMAN

  • Pathway: Protein modification; protein glycosylation.

Interacting Proteins for MGAT3 Gene

Gene Ontology (GO) - Biological Process for MGAT3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006044 N-acetylglucosamine metabolic process IBA 21873635
GO:0006486 protein glycosylation IEA --
GO:0006487 protein N-linked glycosylation ISS --
GO:0008104 protein localization IMP 19403558
GO:0030334 regulation of cell migration IDA 26801611
genes like me logo Genes that share ontologies with MGAT3: view

No data available for SIGNOR curated interactions for MGAT3 Gene

Drugs & Compounds for MGAT3 Gene

(3) Drugs for MGAT3 Gene - From: HMDB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Uridine 5'-diphosphate Experimental Pharma 0

(6) Additional Compounds for MGAT3 Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Uridine diphosphate-N-acetylglucosamine
  • (2R,3R,4R,5S,6R)-3-(acetylamino)-4,5-Dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name)
  • UDP-GlcNAc
  • UDP-N-Acetyl-D-glucosamine
  • UDP-N-Acetylglucosamine
  • URIDINE-diphosphATE-N-acetylglucosamine
528-04-1
genes like me logo Genes that share compounds with MGAT3: view

Transcripts for MGAT3 Gene

mRNA/cDNA for MGAT3 Gene

Unigene Clusters for MGAT3 Gene

Mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase:
Representative Sequences:

CRISPR Products

Clone Products

  • Applied Biological Materials (abm): Clones for MGAT3 - Now 50% OFF >
  • * MGAT3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * MGAT3 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
  • Addgene plasmids for MGAT3

Alternative Splicing Database (ASD) splice patterns (SP) for MGAT3 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b
SP1:
SP2: - -

Relevant External Links for MGAT3 Gene

GeneLoc Exon Structure for
MGAT3
ECgene alternative splicing isoforms for
MGAT3

Expression for MGAT3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MGAT3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MGAT3 Gene

This gene is overexpressed in Brain - Cortex (x4.4).

Protein differential expression in normal tissues from HIPED for MGAT3 Gene

This gene is overexpressed in Heart (58.9) and Pancreas (10.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for MGAT3 Gene



Protein tissue co-expression partners for MGAT3 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of MGAT3 Gene:

MGAT3

SOURCE GeneReport for Unigene cluster for MGAT3 Gene:

Hs.276808

Evidence on tissue expression from TISSUES for MGAT3 Gene

  • Nervous system(4.6)
genes like me logo Genes that share expression patterns with MGAT3: view

No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MGAT3 Gene

Orthologs for MGAT3 Gene

This gene was present in the common ancestor of animals.

Orthologs for MGAT3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MGAT3 35 34
  • 99.31 (n)
OneToOne
dog
(Canis familiaris)
Mammalia MGAT3 35 34
  • 92.54 (n)
OneToOne
cow
(Bos Taurus)
Mammalia MGAT3 35 34
  • 90.91 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Mgat3 17 35 34
  • 86.59 (n)
rat
(Rattus norvegicus)
Mammalia Mgat3 34
  • 86.59 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia MGAT3 35
  • 83 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MGAT3 35
  • 82 (a)
OneToOne
chicken
(Gallus gallus)
Aves MGAT3 35 34
  • 82.44 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MGAT3 35
  • 87 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia mgat3 34
  • 66.26 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.6533 34
zebrafish
(Danio rerio)
Actinopterygii LOC570828 34
  • 66.08 (n)
CABZ01084569.1 35
  • 66 (a)
OneToMany
mgat3a 35
  • 55 (a)
OneToMany
cxcl12a 34
fruit fly
(Drosophila melanogaster)
Insecta CG31849 35
  • 22 (a)
OneToOne
Species where no ortholog for MGAT3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MGAT3 Gene

ENSEMBL:
Gene Tree for MGAT3 (if available)
TreeFam:
Gene Tree for MGAT3 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for MGAT3: view image

Paralogs for MGAT3 Gene

No data available for Paralogs for MGAT3 Gene

Variants for MGAT3 Gene

Sequence variations from dbSNP and Humsavar for MGAT3 Gene

SNP ID Clin Chr 22 pos Variation AA Info Type
rs1000025815 -- 39,467,388(+) C/G/T 5_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000112034 -- 39,481,834(+) T/A genic_upstream_transcript_variant, intron_variant
rs1000189159 -- 39,471,300(+) A/G 5_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000242146 -- 39,476,852(+) A/T 5_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000274613 -- 39,479,737(+) A/G 5_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for MGAT3 Gene

Variant ID Type Subtype PubMed ID
esv2667824 CNV deletion 23128226
esv3647765 CNV loss 21293372
esv3647766 CNV loss 21293372
nsv1072211 CNV deletion 25765185
nsv1144973 CNV deletion 24896259
nsv3628 CNV insertion 18451855
nsv471200 CNV loss 18288195
nsv834199 CNV loss 17160897
nsv955158 CNV deletion 24416366

Variation tolerance for MGAT3 Gene

Residual Variation Intolerance Score: 52.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.12; 22.73% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MGAT3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MGAT3

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MGAT3 Gene

Disorders for MGAT3 Gene

Additional Disease Information for MGAT3

No disorders were found for MGAT3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MGAT3 Gene

Publications for MGAT3 Gene

  1. cDNA cloning, expression, and chromosomal localization of human N-acetylglucosaminyltransferase III (GnT-III). (PMID: 8370666) Ihara Y … Taniguchi N (Journal of biochemistry 1993) 2 3 4 23 58
  2. The role of N-acetylglucosaminyltransferase III and V in the post-transcriptional modifications of E-cadherin. (PMID: 19403558) Pinho SS … Seruca R (Human molecular genetics 2009) 3 4 23 58
  3. Expression of N-Acetylglucosaminyltransferase III Suppresses α2,3-Sialylation, and Its Distinctive Functions in Cell Migration Are Attributed to α2,6-Sialylation Levels. (PMID: 26801611) Lu J … Gu J (The Journal of biological chemistry 2016) 3 4 58
  4. Protective effect of N-glycan bisecting GlcNAc residues on beta-amyloid production in Alzheimer's disease. (PMID: 19776078) Akasaka-Manya K … Endo T (Glycobiology 2010) 3 23 58
  5. An N-glycosylation site on the beta-propeller domain of the integrin alpha5 subunit plays key roles in both its function and site-specific modification by beta1,4-N-acetylglucosaminyltransferase III. (PMID: 19276077) Sato Y … Gu J (The Journal of biological chemistry 2009) 3 23 58

Products for MGAT3 Gene

Sources for MGAT3 Gene

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