Aliases for MGAM Gene
External Ids for MGAM Gene
Previous GeneCards Identifiers for MGAM Gene
This gene encodes maltase-glucoamylase, which is a brush border membrane enzyme that plays a role in the final steps of digestion of starch. The protein has two catalytic sites identical to those of sucrase-isomaltase, but the proteins are only 59% homologous. Both are members of glycosyl hydrolase family 31, which has a variety of substrate specificities. [provided by RefSeq, Jul 2008]
GeneCards Summary for MGAM Gene
MGAM (Maltase-Glucoamylase) is a Protein Coding gene. Diseases associated with MGAM include Glycogen Storage Disease Ii and Diarrhea. Among its related pathways are Glycosaminoglycan metabolism and Galactose metabolism. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and alpha-1,4-glucosidase activity. An important paralog of this gene is MGAM2.
UniProtKB/Swiss-Prot Summary for MGAM Gene
May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing.