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Aliases for MGA Gene
Aliases for MGA Gene
External Ids for MGA Gene
- HGNC: 14010
- Entrez Gene: 23269
- Ensembl: ENSG00000174197
- OMIM: 616061
- UniProtKB: Q8IWI9
Previous GeneCards Identifiers for MGA Gene
- GC15P037399
- GC15P034928
- GC15P039612
- GC15P039677
- GC15P039749
- GC15P041952
- GC15P018801
Summaries for MGA Gene
GeneCards Summary for MGA Gene
MGA (MAX Dimerization Protein MGA) is a Protein Coding gene. Among its related pathways are Pathways Affected in Adenoid Cystic Carcinoma. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and protein dimerization activity. An important paralog of this gene is TBX3.
UniProtKB/Swiss-Prot Summary for MGA Gene
-
Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor (By similarity).
Additional gene information for MGA Gene
- HGNC(14010)
- Entrez Gene(23269)
- Ensembl(ENSG00000174197)
- OMIM(616061)
- UniProtKB(Q8IWI9)
- Open Targets Platform(ENSG00000174197)
- Monarch Initiative
- Search for MGA at DataMed
- Search for MGA at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MGA Gene
Genomics for MGA Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for MGA Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MGA on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MGA
- Top Transcription factor binding sites by QIAGEN in the MGA gene promoter:
-
- c-Myc
- HNF-1
- HNF-1A
- Ik-1
- LCR-F1
- Max
- N-Myc
- POU3F2
Genomic Locations for MGA Gene
Genomic Locations for MGA Gene
- chr15:41,621,224-41,773,081
- (GRCh38/hg38)
- Size:
- 151,858 bases
- Orientation:
- Plus strand
- chr15:41,913,422-42,062,141
- (GRCh37/hg19)
- Size:
- 148,720 bases
- Orientation:
- Plus strand
Genomic View for MGA Gene
Genes around MGA on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 15q15 by HGNC
- 15q15.1 by Entrez Gene
- 15q15.1 by Ensembl
MGA Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MGA Gene
Proteins for MGA Gene
-
Protein details for MGA Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8IWI9-MGAP_HUMAN
- Recommended name:
- MAX gene-associated protein
- Protein Accession:
- Q8IWI9
- B9EGR5
- E7ENI0
- F5H7K2
- Q9H8R3
- Q9H9N7
- Q9UG69
- Q9Y4E9
Protein attributes for MGA Gene
- Size:
- 3065 amino acids
- Molecular mass:
- 336159 Da
- Quaternary structure:
-
- Interacts with MAX. Requires dimerization with MAX for E-box binding (By similarity). Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, MYST1/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Interacts with ZMYND11.
- SequenceCaution:
-
- Sequence=BAB14186.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; Sequence=BAB14543.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
Protein Expression for MGA Gene
Post-translational modifications for MGA Gene
Other Protein References for MGA Gene
- ENSEMBL proteins:
- REFSEQ proteins:
-
- XP_005254300.1
- XP_005254301.1
- XP_005254302.1
- XP_005254303.1
- XP_005254304.1
- XP_005254305.1
- XP_005254306.1
- XP_005254309.1
- XP_005254310.1
- XP_005254311.1
- XP_006720506.1
- XP_006720508.1
- XP_011519699.1
- XP_011519700.1
- XP_011519701.1
- XP_011519702.1
- XP_016877517.1
- XP_016877518.1
- XP_016877519.1
- XP_016877520.1
- XP_016877521.1
- NP_001074010.2
- NP_001157745.1
Antibody Products
- Creative Diagnostics Anti-MGA monoclonal antibody, clone NHB7B5I6
- Creative Biolabs Recombinant Mouse Anti-Human MGA Antibody (clone NHB7B5I6)
- Novus Biologicals Antibodies for MGA
-
Abcam antibodies for MGA
- Invitrogen Antibodies for MGA (AFLGC-MGA)
-
Boster Bio Antibodies for MGA
-
Santa Cruz Biotechnology (SCBT) Antibodies for MGA
- Sino Biological Antibodies for MGA
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MGA
- Origene Custom Protein Services for MGA
- Novus Biologicals proteins for MGA
- antibodies-online: Search results for available MGA related products ranked by validation data
Assay Products
- antibodies-online: Search results for available MGA related products ranked by validation data
-
Signalway ELISA kits for MGA
No data available for DME Specific Peptides for MGA Gene
Domains & Families for MGA Gene
Gene Families for MGA Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Predicted intracellular proteins
- Transcription factors
Protein Domains for MGA Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for MGA Gene
- GenScript: Design optimal peptide antigens:
-
- MGA protein (B9EGR5_HUMAN)
- MAX dimerization protein 5 (MGAP_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8IWI9UniProtKB/Swiss-Prot:
MGAP_HUMAN :- Transcription repression is enhanced or dependent on the presence of the T-box DNA-binding domain.
- Domain:
-
- Transcription repression is enhanced or dependent on the presence of the T-box DNA-binding domain.
Function for MGA Gene
Molecular function for MGA Gene
- UniProtKB/Swiss-Prot Function:
- Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor (By similarity).
Phenotypes From GWAS Catalog for MGA Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | IBA | 21873635 |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | ISM | 19274049 |
| GO:0001102 | RNA polymerase II activating transcription factor binding | IBA | 21873635 |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | IBA | 21873635 |
| GO:0003677 | DNA binding | IEA | -- |
Phenotypes for MGA Gene
- MGI mutant phenotypes for MGA:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for MGA:
-
- Increased vaccinia virus (VACV) infection
- Decreased viability
- Decreased vaccinia virus (VACV) infection
- Strongly decreased CFP-tsO45G cell surface transport
- Increased ionizing radiation sensitivity
- Increased Nanog expression
- Increased caspase activity
- Increased homologous recombination repair frequency
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MGA - Select products 50% OFF >
- * MGA CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for MGA
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MGA
-
Santa Cruz Biotechnology (SCBT) CRISPR for MGA
miRNA for MGA Gene
- miRTarBase miRNAs that target MGA
-
- mmu-miR-223-3p (MIRT009659)
- mmu-miR-17-5p (MIRT010066)
- mmu-miR-340-5p (MIRT010483)
- hsa-miR-335-5p (MIRT018623)
- hsa-miR-21-5p (MIRT030956)
- mmu-miR-1965 (MIRT589550)
- mmu-miR-546 (MIRT589551)
- mmu-miR-1946a (MIRT589552)
- mmu-miR-804 (MIRT592611)
- mmu-miR-1195 (MIRT592612)
- mmu-miR-3089-5p (MIRT592613)
- mmu-miR-665-3p (MIRT592614)
- mmu-miR-706 (MIRT592615)
- mmu-miR-669f-3p (MIRT592616)
- mmu-miR-10b-5p (MIRT592617)
- mmu-miR-10a-5p (MIRT592618)
- mmu-miR-339-5p (MIRT592619)
- mmu-miR-3082-5p (MIRT592620)
- mmu-miR-1935 (MIRT600635)
- mmu-miR-298-5p (MIRT600636)
- mmu-miR-709 (MIRT600637)
- mmu-miR-5135 (MIRT600638)
- mmu-miR-1199-5p (MIRT600639)
- mmu-miR-139-5p (MIRT600640)
- mmu-miR-759 (MIRT600641)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MGA
- Browse OriGene Inhibitory RNA Products For MGA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MGA
Clone Products
- Applied Biological Materials (abm): Clones for MGA - Select products 50% OFF >
- * MGA as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Addgene plasmids for MGA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MGA
Cell Line Products
-
Horizon Cell Lines for MGA
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MGA Gene
Localization for MGA Gene
Subcellular locations from UniProtKB/Swiss-Prot for MGA Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 3 |
| plasma membrane | 1 |
| extracellular | 1 |
| mitochondrion | 1 |
| endosome | 1 |
| golgi apparatus | 1 |
- Cytosol (3)
- Nucleoplasm (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000790 | nuclear chromatin | ISA | -- |
| GO:0005634 | nucleus | IBA | 21873635 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0071339 | MLL1 complex | IDA | 15960975 |
Pathways & Interactions for MGA Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Pathways Affected in Adenoid Cystic Carcinoma | ||
Pathways by source for MGA Gene
1 BioSystems pathway for MGA Gene
Interacting Proteins for MGA Gene
Selected Interacting proteins:
Q8IWI9-MGAP_HUMAN
ENSP00000219905
for MGA Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for MGA
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | IBA | 21873635 |
| GO:0001708 | cell fate specification | IBA | 21873635 |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | IBA | 21873635 |
| GO:0070317 | negative regulation of G0 to G1 transition | TAS | -- |
Transcripts for MGA Gene
mRNA/cDNA for MGA Gene
- 2 REFSEQ mRNAs :
- 19 NCBI additional mRNA sequence :
- 12 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000219905 12042 nts (view in UCSC)
- ENST00000545763 11413 nts (view in UCSC)
- ENST00000561532 532 nts (view in UCSC)
- ENST00000563576 3537 nts (view in UCSC)
- ENST00000564190 3521 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MGA - Select products 50% OFF >
- * MGA CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for MGA
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MGA
-
Santa Cruz Biotechnology (SCBT) CRISPR for MGA
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MGA
- Browse OriGene Inhibitory RNA Products For MGA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MGA
Clone Products
- Applied Biological Materials (abm): Clones for MGA - Select products 50% OFF >
- * MGA as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Addgene plasmids for MGA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MGA
Relevant External Links for MGA Gene
- GeneLoc Exon Structure for
- MGA
Expression for MGA Gene
This gene is overexpressed in Hair follicle (57.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MGA Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MGA
SOURCE GeneReport for Unigene cluster for MGA Gene:
Hs.187569Evidence on tissue expression from TISSUES for MGA Gene
- Nervous system(4.5)
- Gall bladder(3.5)
- Liver(3.3)
- Intestine(3.2)
- Heart(2.6)
- Spleen(2.1)
- Kidney(2.1)
Primer Products
-
OriGene qPCR primer pairs for MGA
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MGA Gene
Orthologs for MGA Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | MGA 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | MGA 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | MGA 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Mga 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Mga 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | MGA 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | MGA 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | MGA 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | MGA 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | mga 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | MGA (2 of 2) 31 |
|
OneToMany | |
| mgaa 31 |
|
OneToMany | |||
| Worm (Caenorhabditis elegans) |
Secernentea | tbx-9 31 |
|
ManyToMany | |
| tbx-8 31 |
|
ManyToMany | |||
| tbx-11 31 |
|
ManyToMany | |||
| tbx-38 31 |
|
ManyToMany | |||
| tbx-43 31 |
|
ManyToMany | |||
| tbx-37 31 |
|
ManyToMany | |||
| tbx-34 31 |
|
ManyToMany | |||
| tbx-42 31 |
|
ManyToMany | |||
| tbx-30 31 |
|
ManyToMany | |||
| tbx-35 31 |
|
ManyToMany | |||
| tbx-39 31 |
|
ManyToMany | |||
| tbx-40 31 |
|
ManyToMany | |||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToOne |
- Species where no ortholog for MGA was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for MGA Gene
- ENSEMBL:
- Gene Tree for MGA (if available)
- TreeFam:
- Gene Tree for MGA (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MGA: view image
Paralogs for MGA Gene
Paralogs for MGA Gene
(8) SIMAP similar genes for MGA Gene using alignment to 6 proteins:
- MGAP_HUMAN
- B9EGR5_HUMAN
- H3BP52_HUMAN
- H3BTF4_HUMAN
- H3BTN2_HUMAN
- H3BU53_HUMAN
Variants for MGA Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MGA Gene
| SNP ID | Clinical significance and condition | Chr 15 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 711106 | Benign: not provided | 41,765,070(+) | G/A | INTRON_VARIANT | |
| 712155 | Benign: not provided | 41,736,607(+) | A/G | MISSENSE_VARIANT | |
| 715531 | Likely Benign: not provided | 41,669,906(+) | A/G | MISSENSE_VARIANT | |
| 715863 | Likely Benign: not provided | 41,766,760(+) | A/C | MISSENSE_VARIANT | |
| 719754 | Benign: not provided | 41,697,032(+) | G/T | INTRON_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1203n106 | CNV | deletion | 24896259 |
| dgv2581n100 | CNV | gain | 25217958 |
| dgv449e214 | CNV | gain | 21293372 |
| esv1466405 | CNV | deletion | 17803354 |
| esv2749621 | CNV | deletion | 23290073 |
| esv2760027 | CNV | loss | 17122850 |
| esv3233790 | CNV | deletion | 24192839 |
| esv3415439 | CNV | insertion | 20981092 |
| esv3552369 | CNV | deletion | 23714750 |
| esv3921 | CNV | loss | 18987735 |
| esv6726 | CNV | loss | 19470904 |
| esv988006 | CNV | deletion | 20482838 |
| esv991459 | CNV | deletion | 20482838 |
| nsv1038894 | CNV | gain | 25217958 |
| nsv1041861 | CNV | loss | 25217958 |
| nsv1044347 | CNV | loss | 25217958 |
| nsv1048655 | CNV | loss | 25217958 |
| nsv1049514 | CNV | gain | 25217958 |
| nsv1069857 | CNV | deletion | 25765185 |
| nsv1147042 | CNV | deletion | 26484159 |
| nsv94393 | CNV | deletion | 16902084 |
| nsv957959 | CNV | deletion | 24416366 |
| nsv976925 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
1.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
11.84;
93.46% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MGA Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MGA Gene
Disorders for MGA Gene
Additional Disease Information for MGA
No disorders were found for MGA Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MGA Gene
Publications for MGA Gene
- Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. (PMID: 15960975) Dou Y … Roeder RG (Cell 2005) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- Mga, a dual-specificity transcription factor that interacts with Max and contains a T-domain DNA-binding motif. (PMID: 10601024) Hurlin PJ … Eisenman RN (The EMBO journal 1999) 3 23
- Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9628581) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1998) 3 4
- Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance. (PMID: 31452512) Pech MF … Settleman J (eLife 2019) 3
ExternalLinks
Products for MGA Gene
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- Custom Assay Services
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- Origene Custom Protein Services for MGA
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MGA
- Browse OriGene Inhibitory RNA Products For MGA
- OriGene qPCR primer pairs for MGA
- OriGene CRISPR knockouts for MGA
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MGA
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- Browse Sino Biological Recombinant Proteins
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- Sino Biological Antibodies for MGA
- Browse Sino Biological Assays
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- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for MGA
- Novus Biologicals proteins for MGA
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- Abcam antibodies for MGA
- Find your target
- Browse Primary Antibodies
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- Invitrogen Antibodies for MGA (AFLGC-MGA)
- VectorBuilder Custom and pre-made DNA vectors for MGA (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for MGA (ie. lentivirus, AAV, adenovirus)
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- VectorBuilder Virus packaging for MGA CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for MGA
- Addgene plasmids for MGA
- antibodies-online: Show 21 available MGA Antibodies ranked by validation data
- Compare Top MGA Antibodies
- antibodies-online: Search results for available MGA related products ranked by validation data
- antibodies-online: Search results for available MGA related products ranked by validation data
- Santa Cruz Biotechnology (SCBT) Antibodies for MGA
- Search Santa Cruz Biotechnology (SCBT) for MGA siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for MGA
- Horizon Cell Lines for MGA
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MGA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MGA
- Search GeneCopoeia for miRNA 3'UTR Target clone products for MGA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MGA
- Boster Bio Antibodies for MGA
- Browse Boster Bio ELISA Kits
- Signalway ELISA kits for MGA
Sources for MGA Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB