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MFSD9 (Major Facilitator Superfamily Domain Containing 9) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include transporter activity and transmembrane transporter activity. An important paralog of this gene is MFSD10.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH02J102735 | Promoter/Enhancer | 2 | EPDnew Ensembl ENCODE CraniofacialAtlas | 329.2 | +0.4 | 387 | 3 | MXD4 CEBPA SMAD5 ZNF217 POLR2A ELF1 ZIC2 KDM6A THAP11 SIN3A | MFSD9 HSALNG0017440 TMEM182 lnc-RFX8-4 lnc-MFSD9-7 SLC9A2 | |
GH02J102761 | Promoter/Enhancer | 1.2 | EPDnew Ensembl ENCODE dbSUPER | 58.6 | -26.0 | -25958 | 3.1 | BCL6 JUND HLF | TMEM182 MFSD9 HSALNG0017440 HSALNG0017443 | |
GH02J102697 | Enhancer | 0.7 | Ensembl ENCODE | 59.8 | +38.6 | 38587 | 1 | REST FOSL1 NFIB NFIA HLF ATF3 ATF2 NFIC MYC | MFSD9 SLC9A2 SLC9A4 HSALNG0017435 HSALNG0017436 | |
GH02J102726 | Enhancer | 0.4 | Ensembl | 88.9 | +9.4 | 9387 | 3.4 | CEBPA CEBPG SPI1 RBFOX2 | MFSD9 SLC9A2 lnc-MFSD9-7 lnc-RFX8-4 | |
GH02J102801 | Enhancer | 1.1 | Ensembl ENCODE dbSUPER | 32.9 | -66.1 | -66142 | 3.1 | BHLHE40 FOXA2 NBN TAL1 RXRA ZBTB33 SKIL BCL6 JUND SPI1 | MFSD9 HSALNG0017443 HSALNG0017440 TMEM182 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0022857 | transmembrane transporter activity | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0055085 | transmembrane transport | IEA | -- |
ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7a | · | 7b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | |||||||||||||||||||||||||||
SP2: | - | - | |||||||||||||||||||||||||||||
SP3: | - | - | - | - | - | ||||||||||||||||||||||||||
SP4: | - | ||||||||||||||||||||||||||||||
SP5: |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | MFSD9 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | MFSD9 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | MFSD9 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Mfsd9 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Mfsd9 30 17 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | MFSD9 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | MFSD9 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | MFSD9 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | MFSD9 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | mfsd9 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | mfsd9 30 31 |
|
OneToOne | |
Worm (Caenorhabditis elegans) |
Secernentea | C53B4.3 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.4725 31 |
|
OneToOne |
SNP ID | Clinical significance and condition | Chr 02 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs34096572 | Benign: not provided. - | 102,718,719(-) |
C/Tp.Ala376Thr NM_032718.5(MFSD9):c.1126G>A (p.Ala376Thr) |
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT | |
rs34977505 | Benign: not provided | 102,718,524(-) |
G/C NM_032718.5(MFSD9):c.1321C>G (p.Pro441Ala) |
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT | |
rs7601509 | Benign: not provided. - | 102,726,887(-) |
C/Ap.Ala129Ser NM_032718.5(MFSD9):c.385G>T (p.Ala129Ser) |
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT | |
VAR_035966 | A breast cancer sample |
p.Gly59Ala |
|||
VAR_035967 | A breast cancer sample |
p.Val84Ala |
No disorders were found for MFSD9 Gene.