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MFSD1 (Major Facilitator Superfamily Domain Containing 1) is a Protein Coding gene. Diseases associated with MFSD1 include Pleomorphic Adenoma Carcinoma and Intraductal Breast Benign Neoplasm. An important paralog of this gene is ENSG00000283761.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0022857 | transmembrane transporter activity | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0055085 | transmembrane transport | IEA | -- |
ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | ||||||||||||||||||||||||||||||||||||||
SP2: | - | ||||||||||||||||||||||||||||||||||||||
SP3: | |||||||||||||||||||||||||||||||||||||||
SP4: |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | MFSD1 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | MFSD1 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | MFSD1 30 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | MFSD1 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Mfsd1 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Mfsd1 30 17 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | MFSD1 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | MFSD1 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | MFSD1 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | mfsd1 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | mfsd1 30 |
|
||
CABZ01033130.1 31 |
|
OneToOne | |||
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP009523 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG12194 30 31 |
|
OneToMany | |
CG8602 31 |
|
OneToMany | |||
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.8860 31 |
|
OneToOne | |
Sea Vase (Ciona intestinalis) |
Ascidiacea | Cin.7889 30 |
|
SNP ID | Clinical significance and condition | Chr 03 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs11551240 | - | p.Ile271Thr | |||
rs17854200 | - | p.Lys168Glu | |||
rs28364680 | - | p.Pro24Ser | |||
rs3765083 | - | p.Ile220Val |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
nsv1004124 | CNV | gain | 25217958 |
nsv1006146 | CNV | loss | 25217958 |
nsv1014255 | CNV | gain | 25217958 |
nsv592123 | CNV | loss | 21841781 |
Disorder | Aliases | PubMed IDs |
---|---|---|
pleomorphic adenoma carcinoma |
|
|
intraductal breast benign neoplasm |
|
|
intraductal papilloma |
|
|