Aliases for MFRP Gene
External Ids for MFRP Gene
Previous GeneCards Identifiers for MFRP Gene
This gene encodes a member of the frizzled-related protein family. The encoded protein plays an important role in eye development and mutations in this gene have been associated with nanophthalmos, posterior microphthalmia, retinitis pigmentosa, foveoschisis, and optic disc drusen. The protein is encoded by a bicistronic transcript which also encodes C1q and tumor necrosis factor related protein 5 (C1QTNF5). [provided by RefSeq, Jun 2013]
GeneCards Summary for MFRP Gene
MFRP (Membrane Frizzled-Related Protein) is a Protein Coding gene. Diseases associated with MFRP include Microphthalmia, Isolated 5 and Nanophthalmos 2. Among its related pathways are MAPK Signaling: Mitogen Stimulation Pathway. An important paralog of this gene is CNTNAP3.
UniProtKB/Swiss-Prot Summary for MFRP Gene
May play a role in eye development.