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This gene encodes a 25-kD microfibril-associated glycoprotein which is a component of microfibrils of the extracellular matrix. The encoded protein promotes attachment of cells to microfibrils via alpha-V-beta-3 integrin. Deficiency of this gene in mice results in neutropenia. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by R... See more...
Aliases for MFAP5 Gene
Aliases for MFAP5 Gene
External Ids for MFAP5 Gene
- HGNC: 29673
- Entrez Gene: 8076
- Ensembl: ENSG00000197614
- OMIM: 601103
- UniProtKB: Q13361
Previous GeneCards Identifiers for MFAP5 Gene
- GC12M008690
- GC12M008689
- GC12M008798
- GC12M008585
- GC12M008806
Summaries for MFAP5 Gene
-
This gene encodes a 25-kD microfibril-associated glycoprotein which is a component of microfibrils of the extracellular matrix. The encoded protein promotes attachment of cells to microfibrils via alpha-V-beta-3 integrin. Deficiency of this gene in mice results in neutropenia. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
GeneCards Summary for MFAP5 Gene
MFAP5 (Microfibril Associated Protein 5) is a Protein Coding gene. Diseases associated with MFAP5 include Aortic Aneurysm, Familial Thoracic 9 and Familial Thoracic Aortic Aneurysm And Aortic Dissection. Among its related pathways are Degradation of the extracellular matrix and Notch Signaling Pathway (WikiPathways). Gene Ontology (GO) annotations related to this gene include extracellular matrix structural constituent. An important paralog of this gene is MFAP2.
UniProtKB/Swiss-Prot Summary for MFAP5 Gene
-
May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity (By similarity). Component of the elastin-associated microfibrils (PubMed:8557636).
Additional gene information for MFAP5 Gene
- HGNC(29673)
- Entrez Gene(8076)
- Ensembl(ENSG00000197614)
- OMIM(601103)
- UniProtKB(Q13361)
- Open Targets Platform(ENSG00000197614)
- Monarch Initiative
- Search for MFAP5 at DataMed
- Search for MFAP5 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MFAP5 Gene
Genomics for MFAP5 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for MFAP5 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MFAP5 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MFAP5
- Top Transcription factor binding sites by QIAGEN in the MFAP5 gene promoter:
-
- Bach1
- Brachyury
- Cdc5
- GCNF
- GCNF-1
- GCNF-2
- HSF2
- Ik-1
- MIF-1
- RFX1
Genomic Locations for MFAP5 Gene
Genomic Locations for MFAP5 Gene
- chr12:8,637,346-8,662,888
- (GRCh38/hg38)
- Size:
- 25,543 bases
- Orientation:
- Minus strand
- chr12:8,789,942-8,815,484
- (GRCh37/hg19)
- Size:
- 25,543 bases
- Orientation:
- Minus strand
Genomic View for MFAP5 Gene
Genes around MFAP5 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12p13.31 by HGNC
- 12p13.31 by Entrez Gene
- 12p13.31 by Ensembl
MFAP5 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MFAP5 Gene
Proteins for MFAP5 Gene
-
Protein details for MFAP5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q13361-MFAP5_HUMAN
- Recommended name:
- Microfibrillar-associated protein 5
- Protein Accession:
- Q13361
- B0AZL6
- D3DUV1
- Q7Z490
Protein attributes for MFAP5 Gene
- Size:
- 173 amino acids
- Molecular mass:
- 19612 Da
- Quaternary structure:
-
- Interacts with TGFB2. Interacts with BMP2. Interacts with FBN1 (via N-terminal domain) and FBN2.
Protein Expression for MFAP5 Gene
Post-translational modifications for MFAP5 Gene
- Forms intermolecular disulfide bonds either with other MAGP-2 molecules or with other components of the microfibrils.
- N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. O-glycan heterogeneity at Thr-54: HexHexNAc (major) and HexHexNAc + sulfate (minor).
-
Glycosylation at Thr54 and Asn79
- NX_Q13361 (NX_Q13361-1)
- Modification sites at PhosphoSitePlus
-
Glycosylation from GlyConnect
- MFAP5_HUMAN (752)
Other Protein References for MFAP5 Gene
Antibody Products
- Creative Diagnostics Anti-MFAP5 (C-terminal) polyclonal antibody
- Novus Biologicals Antibodies for MFAP5
-
Abcam antibodies for MFAP5
- Invitrogen Antibodies for MFAP5 (AFLGC-MFAP5)
-
Biorbyt antibodies for MFAP5
- Sino Biological Antibodies for MFAP5
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for MFAP5
- Origene Custom Protein Services for MFAP5
- Sino Biological Recombinant Proteins for MFAP5
- Sino Biological Cell Lysates for MFAP5
-
Abcam proteins for MFAP5
Assay Products
- RayBiotech Human MAGP-2/MFAP5 ELISA
- antibodies-online: Show 16 available MFAP5 Elisa Kits ranked by validation data
- Compare Top MFAP5 Elisa Kits
-
Quality Products:
-
Signalway ELISA kits for MFAP5
No data available for DME Specific Peptides for MFAP5 Gene
Domains & Families for MFAP5 Gene
Gene Families for MFAP5 Gene
- Human Protein Atlas (HPA):
-
- Disease related genes
- Plasma proteins
- Predicted intracellular proteins
- Predicted secreted proteins
Protein Domains for MFAP5 Gene
Suggested Antigen Peptide Sequences for MFAP5 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ42377 fis, clone UTERU2035469, highly similar to Microfibrillar-associated protein 5 (B3KW70_HUMAN)
- Microfibril-associated glycoprotein 2 (MFAP5_HUMAN)
- cDNA FLJ54936, highly similar to Microfibrillar-associated protein 5 (Q7Z490_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q13361- Family:
-
- Belongs to the MFAP family.
Function for MFAP5 Gene
Molecular function for MFAP5 Gene
- UniProtKB/Swiss-Prot Function:
- May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity (By similarity). Component of the elastin-associated microfibrils (PubMed:8557636).
Phenotypes From GWAS Catalog for MFAP5 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005201 | extracellular matrix structural constituent | TAS,RCA | 25037231 |
Phenotypes for MFAP5 Gene
- MGI mutant phenotypes for MFAP5:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for MFAP5:
Animal Models for MFAP5 Gene
- MGI Knock Outs for MFAP5:
-
- Mfap5 Mfap5<tm1Mech>
Animal Model Products
-
Taconic Biosciences Mouse Models for MFAP5
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MFAP5 - Select products 50% OFF >
- * MFAP5 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
OriGene CRISPR knockouts for MFAP5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MFAP5
-
Santa Cruz Biotechnology (SCBT) CRISPR for MFAP5
miRNA for MFAP5 Gene
- miRTarBase miRNAs that target MFAP5
-
- hsa-miR-124-3p (MIRT022336)
- hsa-miR-6836-3p (MIRT646418)
- hsa-miR-5001-3p (MIRT646419)
- hsa-miR-6829-3p (MIRT646420)
- hsa-miR-6791-3p (MIRT646421)
- hsa-miR-6778-3p (MIRT646422)
- hsa-miR-4726-3p (MIRT646423)
- hsa-miR-6764-5p (MIRT646424)
- hsa-miR-6840-3p (MIRT646425)
- hsa-miR-1915-3p (MIRT646426)
- hsa-miR-190a-3p (MIRT707336)
- hsa-miR-374b-5p (MIRT707337)
- hsa-miR-374a-5p (MIRT707338)
- hsa-miR-5011-5p (MIRT707339)
- hsa-miR-410-3p (MIRT707340)
- hsa-miR-5692c (MIRT707341)
- hsa-miR-5692b (MIRT707342)
- hsa-miR-369-3p (MIRT707343)
- hsa-miR-1277-5p (MIRT707344)
- hsa-miR-6507-5p (MIRT707345)
- hsa-miR-1248 (MIRT761598)
- hsa-miR-1295a (MIRT762344)
- hsa-miR-4747-3p (MIRT771914)
- hsa-miR-5699-5p (MIRT775195)
- hsa-miR-5704 (MIRT775240)
- hsa-miR-874-5p (MIRT782515)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MFAP5
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Clone Products
- Applied Biological Materials (abm): Clones for MFAP5 - Select products 50% OFF >
- * MFAP5 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for MFAP5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MFAP5
Cell Line Products
-
Horizon Cell Lines for MFAP5
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for MFAP5 Gene
Localization for MFAP5 Gene
Subcellular locations from UniProtKB/Swiss-Prot for MFAP5 Gene
- Secreted, extracellular space, extracellular matrix.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| plasma membrane | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001527 | microfibril | ISS | -- |
| GO:0005576 | extracellular region | TAS | -- |
| GO:0031012 | extracellular matrix | IEA | -- |
| GO:0062023 | collagen-containing extracellular matrix | HDA | 25037231 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for MFAP5 Gene
Pathways & Interactions for MFAP5 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Notch Signaling Pathway (WikiPathways) | ||
| 2 | Elastic fibre formation | ||
| 3 | Degradation of the extracellular matrix | ||
| 4 | MFAP5-mediated ovarian cancer cell motility and invasiveness | ||
Pathways by source for MFAP5 Gene
2 BioSystems pathways for MFAP5 Gene
3 Reactome pathways for MFAP5 Gene
1 R&D Systems pathway for MFAP5 Gene
Interacting Proteins for MFAP5 Gene
GPS-Prot Interaction Network for MFAP5
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0030198 | extracellular matrix organization | TAS | -- |
| GO:0048048 | embryonic eye morphogenesis | IBA | 21873635 |
| GO:0060216 | definitive hemopoiesis | ISS | -- |
| GO:0097435 | supramolecular fiber organization | IEA | -- |
No data available for SIGNOR curated interactions for MFAP5 Gene
Transcripts for MFAP5 Gene
mRNA/cDNA for MFAP5 Gene
- 5 REFSEQ mRNAs :
- 17 NCBI additional mRNA sequence :
- 15 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000359478 2872 nts (view in UCSC)
- ENST00000396549 1195 nts (view in UCSC)
- ENST00000433590 2308 nts (view in UCSC)
- ENST00000534833 510 nts (view in UCSC)
- ENST00000535336 566 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MFAP5 - Select products 50% OFF >
- * MFAP5 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for MFAP5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MFAP5
-
Santa Cruz Biotechnology (SCBT) CRISPR for MFAP5
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MFAP5
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Clone Products
- Applied Biological Materials (abm): Clones for MFAP5 - Select products 50% OFF >
- * MFAP5 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for MFAP5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MFAP5
Relevant External Links for MFAP5 Gene
- GeneLoc Exon Structure for
- MFAP5
Expression for MFAP5 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Heart (Cardiovascular System)
- Atrioventricular Node Cells Atrioventricular Node
- Mature Cardiac Fibroblasts Myocardium
- Atrioventricular Node
- Bone (Muscoskeletal System)
-
Fibroblasts
- Mature Cardiac Fibroblasts Myocardium
- Detroit 551
- Skeletal Muscle (Muscoskeletal System)
- Inner Cell Mass (Early Embryonic Tissues)
- Cartilage (Muscoskeletal System)
-
Liver (Hepatobiliary System)
- Mature Mesothelial Cells Liver Lobule
- Dermis (Integumentary System)
-
Placenta (Extraembryonic Tissues)
-
Smooth Muscle (Muscoskeletal System)
-
Testis (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for MFAP5 Gene
This gene is overexpressed in Nerve - Tibial (x6.6), Adipose - Subcutaneous (x5.4), and Uterus (x4.9).
This gene is overexpressed in Gallbladder (11.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for MFAP5 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MFAP5
SOURCE GeneReport for Unigene cluster for MFAP5 Gene:
Hs.512842Evidence on tissue expression from TISSUES for MFAP5 Gene
- Muscle(4.5)
- Liver(4.3)
- Heart(2.7)
Phenotype-based relationships between genes and organs from Gene ORGANizer for MFAP5 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- integumentary
- nervous
- respiratory
- skeletal muscle
- skeleton
Regions:
Head and neck:
- brain
- chin
- cranial nerve
- ear
- eye
- eyelid
- face
- head
- jaw
- mandible
- maxilla
- meninges
- mouth
- pharynx
- skull
Thorax:
- aorta
- chest wall
- heart
- heart valve
- lung
- rib
- rib cage
- sternum
Abdomen:
- abdominal wall
- intestine
Pelvis:
- pelvis
Limb:
- ankle
- digit
- elbow
- finger
- foot
- hand
- hip
- knee
- lower limb
- shoulder
- toe
- upper limb
- wrist
General:
- blood
- blood vessel
- peripheral nervous system
- skin
- spinal column
- vertebrae
Primer Products
-
OriGene qPCR primer pairs for MFAP5
-
OriGene qPCR primer pairs and template standards for MFAP5
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt for MFAP5 Gene
Orthologs for MFAP5 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | MFAP5 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | MFAP5 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | MFAP5 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Mfap5 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Mfap5 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | MFAP5 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | MFAP5 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | MFAP5 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC101734819 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | mfap5 31 |
|
OneToOne |
- Species where no ortholog for MFAP5 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for MFAP5 Gene
- ENSEMBL:
- Gene Tree for MFAP5 (if available)
- TreeFam:
- Gene Tree for MFAP5 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MFAP5: view image
Paralogs for MFAP5 Gene
Variants for MFAP5 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MFAP5 Gene
| SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 636624 | Uncertain Significance: not provided | 8,649,528(-) | C/G | MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT,INTRON_VARIANT | |
| 668293 | Likely Benign: not provided | 8,654,418(-) | G/C | INTRON_VARIANT | |
| 668685 | Likely Benign: not provided | 8,650,537(-) | C/T | NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT,INTRON_VARIANT | |
| 669640 | Benign: not provided | 8,648,486(-) | C/A | INTRON_VARIANT | |
| 674704 | Benign: not provided | 8,660,999(-) | T/A | INTRON_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2667162 | CNV | deletion | 23128226 |
| nsv1051530 | CNV | gain | 25217958 |
Residual Variation Intolerance Score:
56.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.47;
10.19% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MFAP5 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MFAP5 Gene
Disorders for MFAP5 Gene
(12) MalaCards diseases for MFAP5 Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| aortic aneurysm, familial thoracic 9 |
|
|
| familial thoracic aortic aneurysm and aortic dissection |
|
|
| aortic aneurysm |
|
|
| aneurysm |
|
|
| aortic disease |
|
|
Search MFAP5 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
MFAP5_HUMAN- Aortic aneurysm, familial thoracic 9 (AAT9) [MIM:616166]: A disease characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. It is primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance. {ECO:0000269 PubMed:25434006}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for MFAP5
No data available for Genatlas for MFAP5 Gene
Publications for MFAP5 Gene
- The exon structure of the human MAGP-2 gene. Similarity with the MAGP-1 gene is confined to two exons encoding a cysteine-rich region. (PMID: 9792630) Hatzinikolas G … Gibson MA (The Journal of biological chemistry 1998) 2 3 4 23
- Further characterization of proteins associated with elastic fiber microfibrils including the molecular cloning of MAGP-2 (MP25) (PMID: 8557636) Gibson MA … Cleary EG (The Journal of biological chemistry 1996) 2 3 4
- MFAP5 loss-of-function mutations underscore the involvement of matrix alteration in the pathogenesis of familial thoracic aortic aneurysms and dissections. (PMID: 25434006) Barbier M … Boileau C (American journal of human genetics 2014) 3 4
- A gene signature predictive for outcome in advanced ovarian cancer identifies a survival factor: microfibril-associated glycoprotein 2. (PMID: 19962670) Mok SC … Birrer MJ (Cancer cell 2009) 3 23
- Microfibril-associate glycoprotein-2 (MAGP-2) promotes angiogenic cell sprouting by blocking notch signaling in endothelial cells. (PMID: 18417156) Albig AR … Schiemann WP (Microvascular research 2008) 3 23
ExternalLinks
Products for MFAP5 Gene
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- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
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- antibodies-online: Show 12 available MFAP5 Antibodies ranked by validation data
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- antibodies-online: Show 14 available MFAP5 Proteins ranked by validation data
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Sources for MFAP5 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB