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This gene encodes a member of the non-histone lysine methyltransferases. It interacts with its substrate, Kin17, which is involved in DNA repair and replication and mRNA processing. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] See more...
Aliases for METTL22 Gene
Aliases for METTL22 Gene
External Ids for METTL22 Gene
- HGNC: 28368
- NCBI Entrez Gene: 79091
- Ensembl: ENSG00000067365
- OMIM®: 615261
- UniProtKB/Swiss-Prot: Q9BUU2
Previous HGNC Symbols for METTL22 Gene
- C16orf68
Previous GeneCards Identifiers for METTL22 Gene
- GC16P008717
Summaries for METTL22 Gene
-
This gene encodes a member of the non-histone lysine methyltransferases. It interacts with its substrate, Kin17, which is involved in DNA repair and replication and mRNA processing. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
GeneCards Summary for METTL22 Gene
METTL22 (Methyltransferase Like 22) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Protein methylation. Gene Ontology (GO) annotations related to this gene include methyltransferase activity.
UniProtKB/Swiss-Prot Summary for METTL22 Gene
-
Protein N-lysine methyltransferase. In vitro methylates KIN.
Additional gene information for METTL22 Gene
- HGNC (28368)
- NCBI Entrez Gene (79091)
- Ensembl (ENSG00000067365)
- OMIM® (615261)
- UniProtKB/Swiss-Prot (Q9BUU2)
- Open Targets Platform(ENSG00000067365)
- Search for METTL22 at DataMed
- Search for METTL22 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for METTL22 Gene
Genomics for METTL22 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for METTL22 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around METTL22 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for METTL22
Genomic Locations for METTL22 Gene
Latest Assembly
- chr16:8,621,670-8,673,565
- (GRCh38/hg38)
- Size:
- 51,896 bases
- Orientation:
- Plus strand
Previous Assembly
- chr16:8,715,555-8,743,511
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 27,957 bases
- Orientation:
- Plus strand
- chr16:8,715,540-8,740,081
- (GRCh37/hg19 by Ensembl)
- Size:
- 24,542 bases
- Orientation:
- Plus strand
Genomic View for METTL22 Gene
Genes around METTL22 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16p13.2 by HGNC
- 16p13.2 by Entrez Gene
- 16p13.2 by Ensembl
METTL22 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for METTL22 Gene
Proteins for METTL22 Gene
-
Protein details for METTL22 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9BUU2-MET22_HUMAN
- Recommended name:
- Methyltransferase-like protein 22
- Protein Accession:
- Q9BUU2
- B2RD29
- D3DUF2
- Q6XYB4
- Q9HA03
Protein attributes for METTL22 Gene
- Size:
- 404 amino acids
- Molecular mass:
- 44486 Da
- Quaternary structure:
-
- Interacts with members of the heat shock protein 90 and 70 families; these proteins probably are methylation substrates.
Protein Expression for METTL22 Gene
Post-translational modifications for METTL22 Gene
Other Protein References for METTL22 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- Novus Biologicals Antibodies for METTL22
- Invitrogen Antibodies for METTL22 (AFLGC-METTL22)
- antibodies-online: Show 6 available METTL22 Antibodies ranked by validation data
- Compare Top METTL22 Antibodies
-
Quality Products:
Protein products for research
-
OriGene Purified Proteins for METTL22
- Search Origene for MassSpec and Protein Over-expression Lysates for METTL22
- Origene Custom Protein Services for METTL22
- Novus Biologicals proteins for METTL22
- antibodies-online: Show 2 available METTL22 Proteins ranked by validation data
- Compare Top METTL22 Proteins
-
Quality Products:
Assay products for research
No data available for DME Specific Peptides for METTL22 Gene
Domains & Families for METTL22 Gene
Gene Families for METTL22 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for METTL22 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for METTL22 Gene
- GenScript: Design optimal peptide antigens:
-
- Methyltransferase-like protein 22 (MET22_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9BUU2- Family:
-
- Belongs to the methyltransferase superfamily. METTL22 family.
Function for METTL22 Gene
Molecular function for METTL22 Gene
- UniProtKB/Swiss-Prot Function:
- Protein N-lysine methyltransferase. In vitro methylates KIN.
Enzyme Numbers (IUBMB) for METTL22 Gene
Phenotypes From GWAS Catalog for METTL22 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 23349634 |
| GO:0008168 | methyltransferase activity | IEA | -- |
| GO:0008276 | protein methyltransferase activity | IEA,IDA | 23349634 |
| GO:0016279 | protein-lysine N-methyltransferase activity | TAS | -- |
| GO:0016740 | transferase activity | IEA | -- |
Phenotypes for METTL22 Gene
- MGI mutant phenotypes for METTL22:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for METTL22:
Animal Models for METTL22 Gene
- MGI Knock Outs for METTL22:
-
- Mettl22 Mettl22<tm1.1(KOMP)Vlcg>
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for METTL22 - Starting at $85 >
- * METTL22 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for METTL22
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for METTL22
-
Santa Cruz Biotechnology (SCBT) CRISPR for METTL22
miRNA for METTL22 Gene
- miRTarBase miRNAs that target METTL22
-
- hsa-miR-20a-5p (MIRT050513)
- hsa-miR-4298 (MIRT487645)
- hsa-miR-1302 (MIRT487646)
- hsa-miR-4648 (MIRT487647)
- hsa-miR-4306 (MIRT487648)
- hsa-miR-4644 (MIRT487649)
- hsa-miR-185-5p (MIRT487650)
- hsa-miR-4524a-3p (MIRT487651)
- hsa-miR-6770-5p (MIRT487652)
- hsa-miR-194-3p (MIRT487653)
- hsa-miR-376c-3p (MIRT487654)
- hsa-miR-4428 (MIRT487655)
- hsa-miR-1234-3p (MIRT761475)
- hsa-miR-1281 (MIRT762145)
- hsa-miR-1915-3p (MIRT763425)
- hsa-miR-4726-3p (MIRT771658)
- hsa-miR-498 (MIRT772846)
- hsa-miR-6764-5p (MIRT778514)
- hsa-miR-6840-3p (MIRT780152)
- hsa-miR-7107-5p (MIRT781416)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for METTL22
- Browse OriGene Inhibitory RNA Products For METTL22
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for METTL22
Clone products for research
- Applied Biological Materials (abm): Clones for METTL22 - Starting at $45 >
- * METTL22 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for METTL22
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for METTL22
Cell Lines for research
-
Horizon Cell Lines for METTL22
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for METTL22 Gene
Localization for METTL22 Gene
Subcellular locations from UniProtKB/Swiss-Prot for METTL22 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
| endoplasmic reticulum | 1 |
- Nucleoli rim (3)
- Nucleoplasm (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA,IDA | 23349634 |
| GO:0005654 | nucleoplasm | IDA,TAS | -- |
| GO:0005730 | nucleolus | IDA | -- |
| GO:0032991 | protein-containing complex | IDA | 23349634 |
Pathways & Interactions for METTL22 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metabolism of proteins | ||
| 2 | Protein methylation | ||
Pathways by source for METTL22 Gene
3 Reactome pathways for METTL22 Gene
Interacting Proteins for METTL22 Gene
GPS-Prot Interaction Network for METTL22
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006479 | protein methylation | IEA,TAS | -- |
| GO:0018022 | peptidyl-lysine methylation | IEA | -- |
| GO:0032259 | methylation | IEA | -- |
No data available for SIGNOR curated interactions for METTL22 Gene
Transcripts for METTL22 Gene
mRNA/cDNA for METTL22 Gene
- 1 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 18 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000163678 1510 nts (view in UCSC)
- ENST00000381920 4974 nts (view in UCSC)
- ENST00000561758 1312 nts (view in UCSC)
- ENST00000561993 656 nts (view in UCSC)
- ENST00000562151 520 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for METTL22 - Starting at $85 >
- * METTL22 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for METTL22
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for METTL22
-
Santa Cruz Biotechnology (SCBT) CRISPR for METTL22
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for METTL22
- Browse OriGene Inhibitory RNA Products For METTL22
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for METTL22
Clone products for research
- Applied Biological Materials (abm): Clones for METTL22 - Starting at $45 >
- * METTL22 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for METTL22
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for METTL22
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | · | 10c | · | 10d | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP14: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP16: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP17: |
| ExUns: | 14 | ^ | 15a | · | 15b | ^ | 16a | · | 16b | · | 16c | · | 16d | ^ | 17a | · | 17b | · | 17c | ^ | 18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||
| SP2: | - | - | |||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||
| SP4: | - | - | - | ||||||||||||||||||
| SP5: | - | - | |||||||||||||||||||
| SP6: | |||||||||||||||||||||
| SP7: | |||||||||||||||||||||
| SP8: | - | - | - | ||||||||||||||||||
| SP9: | |||||||||||||||||||||
| SP10: | |||||||||||||||||||||
| SP11: | |||||||||||||||||||||
| SP12: | |||||||||||||||||||||
| SP13: | |||||||||||||||||||||
| SP14: | |||||||||||||||||||||
| SP15: | |||||||||||||||||||||
| SP16: | |||||||||||||||||||||
| SP17: |
Relevant External Links for METTL22 Gene
- GeneLoc Exon Structure for
- METTL22
Expression for METTL22 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for METTL22 Gene
This gene is overexpressed in Muscle - Skeletal (x4.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for METTL22 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for METTL22
SOURCE GeneReport for Unigene cluster for METTL22 Gene:
Hs.306380Evidence on tissue expression from TISSUES for METTL22 Gene
- Nervous system(4.2)
- Lung(4.1)
- Liver(4.1)
Primer products for research
-
OriGene qPCR primer pairs for METTL22
Gene Expression Assays for research
No data available for Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for METTL22 Gene
Orthologs for METTL22 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | METTL22 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Mettl22 30 |
|
||
| Dog (Canis familiaris) |
Mammalia | METTL22 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Mettl22 30 17 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | METTL22 30 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | METTL22 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | METTL22 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | METTL22 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | METTL22 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | mettl22 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | mettl22 30 31 |
|
OneToOne | |
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG10584 30 31 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP011879 30 |
|
||
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT1G79915 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os06g0639300 30 |
|
- Species where no ortholog for METTL22 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for METTL22 Gene
- ENSEMBL:
- Gene Tree for METTL22 (if available)
- TreeFam:
- Gene Tree for METTL22 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for METTL22: view image
Paralogs for METTL22 Gene
No data available for Paralogs for METTL22 Gene
Variants for METTL22 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for METTL22 Gene
| SNP ID | Clinical significance and condition | Chr 16 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1731000 | - |
p.Ala366Thr |
|||
| rs2270286 | - |
p.Trp59Ser |
|||
| rs2302607 | - |
p.Ala219Thr |
|||
| rs55747257 | - |
p.Glu375Lys |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1261959 | CNV | insertion | 17803354 |
| esv1322482 | CNV | insertion | 17803354 |
| esv2762154 | CNV | gain | 21179565 |
| esv3416142 | CNV | insertion | 20981092 |
| esv3441939 | CNV | insertion | 20981092 |
| esv3570276 | CNV | gain | 25503493 |
| esv3582003 | CNV | loss | 25503493 |
| esv3892786 | CNV | loss | 25118596 |
| nsv1037325 | CNV | gain | 25217958 |
| nsv1047172 | CNV | gain | 25217958 |
| nsv1144754 | CNV | deletion | 24896259 |
| nsv571406 | CNV | gain | 21841781 |
| nsv827546 | CNV | gain | 20364138 |
Residual Variation Intolerance Score:
90.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
7.15;
80.73% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for METTL22 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for METTL22 Gene
Disorders for METTL22 Gene
Additional Disease Information for METTL22
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No disorders were found for METTL22 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for METTL22 Gene
Publications for METTL22 Gene
- Methylation of the DNA/RNA-binding protein Kin17 by METTL22 affects its association with chromatin. (PMID: 24140279) Cloutier P … Coulombe B (Journal of proteomics 2014) 2 3
- A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity. (PMID: 23349634) Cloutier P … Coulombe B (PLoS genetics 2013) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3
- An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y … Zou H (Journal of proteomics 2014) 4
ExternalLinks
Products for METTL22 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for METTL22
- Search Origene for MassSpec and Protein Over-expression Lysates for METTL22
- Origene Custom Protein Services for METTL22
- Origene shrna, sirna, and RNAi products in human, mouse, rat for METTL22
- Browse OriGene Inhibitory RNA Products For METTL22
- OriGene qPCR primer pairs for METTL22
- OriGene CRISPR knockouts for METTL22
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For METTL22
- Sino Biological Human cDNA Clone for METTL22
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for METTL22
- Novus Biologicals proteins for METTL22
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for METTL22 (AFLGC-METTL22)
- VectorBuilder Custom and pre-made DNA vectors for METTL22 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for METTL22 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for METTL22 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for METTL22 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for METTL22
- antibodies-online: Show 6 available METTL22 Antibodies ranked by validation data
- Compare Top METTL22 Antibodies
- Quality Products:
- antibodies-online: Search results for available METTL22 related products ranked by validation data
- antibodies-online: Show 2 available METTL22 Proteins ranked by validation data
- Compare Top METTL22 Proteins
- Quality Products:
- Horizon Cell Lines for METTL22
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for METTL22
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for METTL22
- Search GeneCopoeia for miRNA 3'UTR Target clone products for METTL22
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for METTL22
Sources for METTL22 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB