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Aliases for METTL21EP Gene

Aliases for METTL21EP Gene

  • Methyltransferase Like 21E, Pseudogene 2 3 5
  • Methyltransferase Like 21C Pseudogene 1 2 3
  • METTL21CP1 3 4
  • EC 2.1.1.- 4

External Ids for METTL21EP Gene

Previous HGNC Symbols for METTL21EP Gene

  • METTL21CP1

Previous GeneCards Identifiers for METTL21EP Gene

  • GC13P103535

Summaries for METTL21EP Gene

GeneCards Summary for METTL21EP Gene

METTL21EP (Methyltransferase Like 21E, Pseudogene) is a Pseudogene. Gene Ontology (GO) annotations related to this gene include methyltransferase activity.

UniProtKB/Swiss-Prot for METTL21EP Gene

  • Protein-lysine methyltransferase.

Additional gene information for METTL21EP Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for METTL21EP Gene

Genomics for METTL21EP Gene

GeneHancer (GH) Regulatory Elements for METTL21EP Gene

Promoters and enhancers for METTL21EP Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13I102877 Enhancer 0.5 ENCODE 567.4 -1.0 -1009 3.1 POLR2A HLF CEBPA ZNF600 ATF2 METTL21EP GC13M102876
GH13I102844 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 11.3 -33.6 -33599 3.9 HDGF PKNOX1 SMAD1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 IRF4 YY1 ERCC5 BIVM TEX30 METTL21EP TPP2 CCDC168 LINC00283 METTL21C GC13P102835 GC13M102871
GH13I102772 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 6.3 -106.4 -106397 2.6 HDGF ATF1 SIN3A GLI4 YY1 POLR2B ZNF766 GLIS2 CBX5 ZNF207 PIR36999 TEX30 ERCC5 TPP2 METTL21EP
GH13I102798 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 5.1 -80.3 -80271 3.7 PKNOX1 SMAD1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF207 ZNF143 BIVM KDELC1 BIVM-ERCC5 METTL21EP GC13M102806
GH13I102825 Enhancer 1 Ensembl ENCODE dbSUPER 8.8 -53.9 -53856 2 JUN CEBPB EP300 RAD21 RFX5 JUND STAT3 SMC3 FOS CCDC168 LINC00283 METTL21C ENSG00000272542 METTL21EP GC13P102835 RNY5P8 BIVM-ERCC5 BIVM
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around METTL21EP on UCSC Golden Path with GeneCards custom track

Genomic Locations for METTL21EP Gene

Genomic Locations for METTL21EP Gene
chr13:102,880,099-102,896,033
(GRCh38/hg38)
Size:
15,935 bases
Orientation:
Plus strand
chr13:103,532,449-103,548,383
(GRCh37/hg19)

Genomic View for METTL21EP Gene

Genes around METTL21EP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
METTL21EP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for METTL21EP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for METTL21EP Gene

Proteins for METTL21EP Gene

  • Protein details for METTL21EP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NDL7-MT21E_HUMAN
    Recommended name:
    Putative methyltransferase-like protein 21E pseudogene
    Protein Accession:
    A6NDL7

    Protein attributes for METTL21EP Gene

    Size:
    271 amino acids
    Molecular mass:
    31188 Da
    Quaternary structure:
    No Data Available

neXtProt entry for METTL21EP Gene

Post-translational modifications for METTL21EP Gene

No Post-translational modifications

No data available for DME Specific Peptides for METTL21EP Gene

Domains & Families for METTL21EP Gene

Protein Domains for METTL21EP Gene

Graphical View of Domain Structure for InterPro Entry

A6NDL7

UniProtKB/Swiss-Prot:

MT21E_HUMAN :
  • Belongs to the methyltransferase superfamily. METTL21 family.
Family:
  • Belongs to the methyltransferase superfamily. METTL21 family.
genes like me logo Genes that share domains with METTL21EP: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for METTL21EP Gene

Function for METTL21EP Gene

Molecular function for METTL21EP Gene

UniProtKB/Swiss-Prot Function:
Protein-lysine methyltransferase.

Enzyme Numbers (IUBMB) for METTL21EP Gene

Phenotypes From GWAS Catalog for METTL21EP Gene

Gene Ontology (GO) - Molecular Function for METTL21EP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008168 methyltransferase activity IEA --
genes like me logo Genes that share ontologies with METTL21EP: view

Animal Model Products

Clone Products

No data available for Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for METTL21EP Gene

Localization for METTL21EP Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for METTL21EP Gene

Pathways & Interactions for METTL21EP Gene

SuperPathways for METTL21EP Gene

No Data Available

Interacting Proteins for METTL21EP Gene

Gene Ontology (GO) - Biological Process for METTL21EP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0032259 methylation IEA --
genes like me logo Genes that share ontologies with METTL21EP: view

No data available for Pathways by source and SIGNOR curated interactions for METTL21EP Gene

Drugs & Compounds for METTL21EP Gene

No Compound Related Data Available

Transcripts for METTL21EP Gene

mRNA/cDNA for METTL21EP Gene

(2) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for METTL21EP Gene

Methyltransferase like 21E, pseudogene:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for METTL21EP Gene

No ASD Table

Relevant External Links for METTL21EP Gene

GeneLoc Exon Structure for
METTL21EP
ECgene alternative splicing isoforms for
METTL21EP

Expression for METTL21EP Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for METTL21EP Gene

mRNA differential expression in normal tissues according to GTEx for METTL21EP Gene

This gene is overexpressed in Muscle - Skeletal (x6.8) and Heart - Left Ventricle (x5.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for METTL21EP Gene



NURSA nuclear receptor signaling pathways regulating expression of METTL21EP Gene:

METTL21EP

SOURCE GeneReport for Unigene cluster for METTL21EP Gene:

Hs.660773
genes like me logo Genes that share expression patterns with METTL21EP: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for METTL21EP Gene

Orthologs for METTL21EP Gene

Evolution for METTL21EP Gene

ENSEMBL:
Gene Tree for METTL21EP (if available)
TreeFam:
Gene Tree for METTL21EP (if available)

No data available for Orthologs for METTL21EP Gene

Paralogs for METTL21EP Gene

(3) SIMAP similar genes for METTL21EP Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with METTL21EP: view

No data available for Paralogs for METTL21EP Gene

Variants for METTL21EP Gene

Sequence variations from dbSNP and Humsavar for METTL21EP Gene

SNP ID Clin Chr 13 pos Variation AA Info Type
rs1000019752 -- 102,883,275(+) C/T intron_variant
rs1000114652 -- 102,889,427(+) C/A/G intron_variant
rs1000267606 -- 102,895,754(+) A/G non_coding_transcript_variant
rs1000273581 -- 102,889,200(+) T/C intron_variant
rs1000560744 -- 102,882,938(+) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for METTL21EP Gene

Variant ID Type Subtype PubMed ID
nsv562981 CNV gain 21841781

Additional Variant Information for METTL21EP Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
METTL21EP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for METTL21EP Gene

Disorders for METTL21EP Gene

Additional Disease Information for METTL21EP

No disorders were found for METTL21EP Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for METTL21EP Gene

Publications for METTL21EP Gene

  1. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood HD … Lan Q (Occupational and environmental medicine 2009) 3 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58
  3. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A … Ross MT (Nature 2004) 4 58

Products for METTL21EP Gene

Sources for METTL21EP Gene

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