Aliases for METTL21A Gene
External Ids for METTL21A Gene
Previous HGNC Symbols for METTL21A Gene
Previous GeneCards Identifiers for METTL21A Gene
GeneCards Summary for METTL21A Gene
METTL21A (Methyltransferase Like 21A) is a Protein Coding gene. Diseases associated with METTL21A include Bardet-Biedl Syndrome 5 and Pontocerebellar Hypoplasia, Type 2A. Among its related pathways are Metabolism of proteins and Protein methylation. Gene Ontology (GO) annotations related to this gene include methyltransferase activity and Hsp70 protein binding. An important paralog of this gene is EEF1AKMT3.
UniProtKB/Swiss-Prot Summary for METTL21A Gene
Protein-lysine methyltransferase that selectively trimethylates residues in heat shock protein 70 (HSP70) family members. Contributes to the in vivo trimethylation of Lys residues in HSPA1 and HSPA8. In vitro methylates 'Lys-561' in HSPA1, 'Lys-564' in HSPA2, 'Lys-585' in HSPA5, 'Lys-563' in HSPA6 and 'Lys-561' in HSPA8.