Aliases for METTL1 Gene
External Ids for METTL1 Gene
Previous HGNC Symbols for METTL1 Gene
Previous GeneCards Identifiers for METTL1 Gene
This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X. [provided by RefSeq, Jul 2008]
GeneCards Summary for METTL1 Gene
METTL1 (Methyltransferase Like 1) is a Protein Coding gene. Among its related pathways are MAPK-Erk Pathway and tRNA processing. Gene Ontology (GO) annotations related to this gene include tRNA binding and tRNA (guanine-N7-)-methyltransferase activity.
UniProtKB/Swiss-Prot for METTL1 Gene
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.