Aliases for METAP1 Gene
External Ids for METAP1 Gene
Previous GeneCards Identifiers for METAP1 Gene
GeneCards Summary for METAP1 Gene
METAP1 (Methionyl Aminopeptidase 1) is a Protein Coding gene. Diseases associated with METAP1 include Microsporidiosis. Among its related pathways are Signaling by GPCR and Metabolism of fat-soluble vitamins. Gene Ontology (GO) annotations related to this gene include hydrolase activity and metalloexopeptidase activity. An important paralog of this gene is METAP1D.
UniProtKB/Swiss-Prot Summary for METAP1 Gene
Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Required for normal progression through the cell cycle.