Aliases for MEST Gene
Aliases for MEST Gene
External Ids for MEST Gene
- HGNC: 7028
- Entrez Gene: 4232
- Ensembl: ENSG00000106484
- OMIM: 601029
- UniProtKB: Q5EB52
Previous GeneCards Identifiers for MEST Gene
- GC07P128602
- GC07P129665
- GC07P129679
- GC07P129719
- GC07P129913
- GC07P130126
- GC07P124488
Summaries for MEST Gene
-
This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15. [provided by RefSeq, Dec 2011]
GeneCards Summary for MEST Gene
MEST (Mesoderm Specific Transcript) is a Protein Coding gene. Diseases associated with MEST include Silver-Russell Syndrome and Retinitis Pigmentosa 4. Gene Ontology (GO) annotations related to this gene include hydrolase activity.
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MEST Gene
Genomics for MEST Gene
GeneHancer (GH) Regulatory Elements for MEST Gene
Promoters and enhancers for MEST Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around MEST on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the MEST gene promoter:
-
- NF-AT1
- NF-AT4
- LyF-1
- NF-AT
Regulatory Element Products
Genomic Locations for MEST Gene
Genomic Locations for MEST Gene
- chr7:130,486,171-130,506,465
- (GRCh38/hg38)
- Size:
- 20,295 bases
- Orientation:
- Plus strand
- chr7:130,126,012-130,146,133
- (GRCh37/hg19)
- Size:
- 20,122 bases
- Orientation:
- Plus strand
Genomic View for MEST Gene
Genes around MEST on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 7q32.2 by Entrez Gene
- 7q32.2 by HGNC
- 7q32.2 by Ensembl
MEST Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MEST Gene
Proteins for MEST Gene
-
Protein details for MEST Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5EB52-MEST_HUMAN
- Recommended name:
- Mesoderm-specific transcript homolog protein
- Protein Accession:
- Q5EB52
- B2R6S1
- O14973
- O15007
- Q6AI49
- Q92571
Protein attributes for MEST Gene
- Size:
- 335 amino acids
- Molecular mass:
- 38830 Da
- Quaternary structure:
- No Data Available
Protein Expression for MEST Gene
Post-translational modifications for MEST Gene
Other Protein References for MEST Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for MEST
- Novus Biologicals Antibodies for MEST
-
Abcam antibodies for MEST
- Invitrogen Antibodies for MEST
- GeneTex MEST Antibody for MEST
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for MEST
- Origene Custom Protein Services for MEST
- antibodies-online: Search results for 4 available MEST Proteins ranked by validation data
- Compare Top MEST Proteins
-
Quality Products:
- Search GeneTex for Proteins for MEST
-
Abcam proteins for MEST
Assay Products
- antibodies-online: Search results for 5 available MEST Elisa Kits ranked by validation data
- Compare Top MEST Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for MEST Gene
Domains & Families for MEST Gene
Gene Families for MEST Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted secreted proteins
Protein Domains for MEST Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for MEST Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q5EB52- Family:
-
- Belongs to the AB hydrolase superfamily.
Function for MEST Gene
Molecular function for MEST Gene
- GENATLAS Biochemistry:
- mesoderm-specific transcript,expressed in fetal tissues from the paternal chromosome and in hydatidiform mole of androgenic origin,identical to the murine imprinted gene Peg1,unlikely to be a contributor to Silver-Russell syndrome with aberrant imprinting in invasive breast carcinomas
Enzyme Numbers (IUBMB) for MEST Gene
Phenotypes From GWAS Catalog for MEST Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016787 | hydrolase activity | IEA | -- |
Phenotypes for MEST Gene
- MGI mutant phenotypes for MEST:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for MEST:
-
- Increased shRNA abundance (Z-score > 2)
- Increased G1 DNA content
- Decreased shRNA abundance (Z-score < -2)
- Upregulation of Wnt/beta-catenin pathway after WNT3A stimulation
- Decreased viability in esophageal squamous lineage
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- Increased transferrin (TF) endocytosis
Animal Models for MEST Gene
- MGI Knock Outs for MEST:
-
- Mest Mest<tm1Masu>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MEST
-
CRISPR Products
-
OriGene CRISPR knockouts for MEST
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MEST
- genomics-online: gRNA clones - Search results for 163 available MEST gene related products
- Overview of 163 available MEST gene related products
- Applied Biological Materials CRISPR for MEST
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MEST
- GenScript: Design CRISPR guide RNA sequences for MEST
miRNA for MEST Gene
- miRTarBase miRNAs that target MEST
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for MEST
- Browse OriGene Inhibitory RNA Products For MEST
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MEST
- genomics-online: shRNA clones - Search results for 163 available MEST gene related products
- Overview of 163 available MEST gene related products
Clone Products
- Sino Biological Human cDNA Clone for MEST
- VectorBuilder custom plasmid, inducible vectors for MEST
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MEST
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MEST
- Applied Biological Materials Clones for MEST
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for MEST
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MEST Gene
Localization for MEST Gene
Subcellular locations from UniProtKB/Swiss-Prot for MEST Gene
- Endoplasmic reticulum membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| endoplasmic reticulum | 5 |
| golgi apparatus | 4 |
| cytosol | 2 |
| peroxisome | 1 |
| nucleus | 1 |
| lysosome | 1 |
- Cytosol (2)
- Golgi apparatus (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005783 | endoplasmic reticulum | ISS | -- |
| GO:0005789 | endoplasmic reticulum membrane | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
| GO:0070062 | extracellular exosome | HDA | 19199708 |
Pathways & Interactions for MEST Gene
No Data Available
Interacting Proteins for MEST Gene
GPS-Prot Interaction Network for MEST
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007498 | mesoderm development | TAS | 9158153 |
| GO:0010883 | regulation of lipid storage | IBA | -- |
No data available for Pathways by source and SIGNOR curated interactions for MEST Gene
Transcripts for MEST Gene
mRNA/cDNA for MEST Gene
- (10) REFSEQ mRNAs :
- (15) Additional mRNA sequences :
- (552) Selected AceView cDNA sequences:
- (17) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000341441 2443 bps (uc003vqc.4)
- ENST00000416162 2337 bps (uc003vqd.4)
- ENST00000427521 2473 bps (uc064iaj.1)
- ENST00000378576 2192 bps (uc064iak.1)
- ENST00000399874 390 bps (uc064ial.1)
Unigene Clusters for MEST Gene
- Mesoderm specific transcript:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for MEST
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MEST
- genomics-online: gRNA clones - Search results for 163 available MEST gene related products
- Overview of 163 available MEST gene related products
- Applied Biological Materials CRISPR for MEST
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MEST
- GenScript: Design CRISPR guide RNA sequences for MEST
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for MEST
- Browse OriGene Inhibitory RNA Products For MEST
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MEST
- genomics-online: shRNA clones - Search results for 163 available MEST gene related products
- Overview of 163 available MEST gene related products
Clone Products
- Sino Biological Human cDNA Clone for MEST
- VectorBuilder custom plasmid, inducible vectors for MEST
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MEST
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MEST
- Applied Biological Materials Clones for MEST
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | · | 12c | ^ | 13 | ^ | 14a | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP16: | - | - |
| ExUns: | 14b | ^ | 15a | · | 15b | · | 15c | ^ | 16a | · | 16b | ^ | 17 | ^ | 18a | · | 18b | · | 18c | · | 18d |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||
| SP4: | - | - | - | - | |||||||||||||||||
| SP5: | |||||||||||||||||||||
| SP6: | - | - | - | - | |||||||||||||||||
| SP7: | |||||||||||||||||||||
| SP8: | |||||||||||||||||||||
| SP9: | |||||||||||||||||||||
| SP10: | |||||||||||||||||||||
| SP11: | |||||||||||||||||||||
| SP12: | |||||||||||||||||||||
| SP13: | |||||||||||||||||||||
| SP14: | |||||||||||||||||||||
| SP15: | |||||||||||||||||||||
| SP16: |
Expression for MEST Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Epithelial Cells
- Bipotent Endocrine/Duct Progenitor Cells Dorsal Pancreatic Bud
- Presumptive Podocytes Podocyte Layer
- Bipotent Endocrine/Duct Progenitor Cells Ventral Pancreatic Bud
-
Brain (Nervous System)
- Mature Endothelial Cells Blood Brain Barrier
- Endothelial Cells Blood Brain Barrier
- N2/LSB/S/F8-induced cells(Kriks S et. al. 2011)
-
Ovary (Reproductive System)
- Pre-Granulosa Cells Primordial Follicle
- Ovarian Mesenchymal Stroma Cells Ovary Interstitium
-
Pancreas (Endocrine System)
- Bipotent Endocrine/Duct Progenitor Cells Dorsal Pancreatic Bud
- Bipotent Endocrine/Duct Progenitor Cells Ventral Pancreatic Bud
-
Endothelium (Cardiovascular System)
- Mature Endothelial Cells Blood Brain Barrier
- Endothelial Cells Blood Brain Barrier
- Neural Tube (Nervous System)
- Adipose (Muscoskeletal System)
-
Kidney (Urinary System)
- Presumptive Podocytes Podocyte Layer
-
Blood (Hematopoietic System)
- Megakaryocyte-Erythroid Precursor Cells Hematopoietic Bone Marrow
-
Testis (Reproductive System)
- Testicular Interstitial Cells Testis Interstitium
-
Heart (Cardiovascular System)
- Cardiac Fibroblasts Myocardium
-
Fibroblasts
- Cardiac Fibroblasts Myocardium
- Neural Ectoderm (Nervous System)
-
Placenta (Extraembryonic Tissues)
-
Spleen (Hematopoietic System)
mRNA differential expression in normal tissues according to GTEx for MEST Gene
This gene is overexpressed in Adipose - Visceral (Omentum) (x8.9), Adipose - Subcutaneous (x6.0), and Adrenal Gland (x4.0).
This gene is overexpressed in Placenta (28.3) and Adipocyte (19.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MEST Gene
NURSA nuclear receptor signaling pathways regulating expression of MEST Gene:
MESTSOURCE GeneReport for Unigene cluster for MEST Gene:
Hs.270978mRNA Expression by UniProt/SwissProt for MEST Gene:
Q5EB52-MEST_HUMAN
Tissue specificity:
Highly expressed in hydatidiform moles, but barely expressed in dermoid cysts. Biallelic expression is detected in blood lymphocytes. Seems to imprinted in an isoform-specific manner rather than in a tissue-specific manner in lymphocytes. Isoform 1 is expressed only from the paternal allele. Isoform 2 is expressed from both the paternal allele and the maternal allele.
Evidence on tissue expression from TISSUES for MEST Gene
- Muscle(4.4)
- Intestine(4.3)
- Nervous system(4)
- Heart(3.1)
- Lung(2.5)
Primer Products
-
OriGene qPCR primer pairs and template standards for MEST
-
OriGene qPCR primer pairs for MEST
- genomics-online: primer clones - Search results for 163 available MEST gene related products
- Overview of 163 available MEST gene related products
Gene Expression Assay Products
No data available for Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for MEST Gene
Orthologs for MEST Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | MEST 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | MEST 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | MEST 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Mest 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Mest 16 34 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | MEST 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | MEST 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | MEST 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | MEST 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | mest 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | mest 34 33 33 |
|
OneToOne | |
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.11262 33 |
|
- Species where no ortholog for MEST was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for MEST Gene
- ENSEMBL:
- Gene Tree for MEST (if available)
- TreeFam:
- Gene Tree for MEST (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MEST: view image
Paralogs for MEST Gene
Pseudogenes.org Pseudogenes for MEST Gene
No data available for Paralogs for MEST Gene
Variants for MEST Gene
| SNP ID | Clin | Chr 07 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs863223353 | likely-pathogenic, Childhood-Onset Schizophrenia | 130,499,898(+) | C/T | coding_sequence_variant, missense_variant | |
| rs1000112642 | -- | 130,499,205(+) | G/A | intron_variant | |
| rs1000379468 | -- | 130,488,957(+) | G/A | genic_upstream_transcript_variant, intron_variant | |
| rs1000811781 | -- | 130,493,595(+) | G/A | intron_variant | |
| rs1001391380 | -- | 130,504,520(+) | T/C | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3572140 | CNV | loss | 25503493 |
| nsv472521 | CNV | novel sequence insertion | 20440878 |
| nsv472979 | CNV | novel sequence insertion | 20440878 |
| nsv474824 | CNV | novel sequence insertion | 20440878 |
| nsv475312 | CNV | novel sequence insertion | 20440878 |
| nsv476708 | CNV | novel sequence insertion | 20440878 |
| nsv477727 | CNV | novel sequence insertion | 20440878 |
| nsv478321 | CNV | novel sequence insertion | 20440878 |
| nsv479379 | CNV | novel sequence insertion | 20440878 |
| nsv481112 | CNV | novel sequence insertion | 20440878 |
| nsv481143 | CNV | novel sequence insertion | 20440878 |
| nsv481360 | CNV | novel sequence insertion | 20440878 |
| nsv481618 | CNV | novel sequence insertion | 20440878 |
| nsv831130 | CNV | loss | 17160897 |
| nsv831131 | CNV | loss | 17160897 |
| nsv966888 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
41.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.98;
20.20% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MEST Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MEST Gene
Disorders for MEST Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| silver-russell syndrome |
|
|
| retinitis pigmentosa 4 |
|
|
| childhood-onset schizophrenia |
|
|
| arts syndrome |
|
|
| diabetes mellitus, transient neonatal, 1 |
|
|
Search MEST in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for MEST
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for MEST Gene
Publications for MEST Gene
- Genomic imprinting and chromosomal localization of the human MEST gene. (PMID: 8884280) Nishita Y … Takagi N (Genomics 1996) 2 3 4 22 58
- Defective neuronal migration and inhibition of bipolar to multipolar transition of migrating neural cells by Mesoderm-Specific Transcript, Mest, in the developing mouse neocortex. (PMID: 28501506) Ji L … Huh SO (Neuroscience 2017) 2 3 58
- Genetic susceptibility to distinct bladder cancer subphenotypes. (PMID: 19692168) Guey LT … EPICURO/Spanish Bladder Cancer Study investigators (European urology 2010) 3 44 58
- Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". (PMID: 20628624) Johnatty SE … Australian Cancer Study (Ovarian Cancer) (PLoS genetics 2010) 3 44 58
- Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. (PMID: 19170196) Shen M … Lan Q (Environmental and molecular mutagenesis 2009) 3 44 58
Products for MEST Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for MEST
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for MEST
- Origene Custom Protein Services for MEST
- Origene sirna, shrna, and RNAi products in human, mouse, rat for MEST
- Browse OriGene Inhibitory RNA Products For MEST
- OriGene qPCR primer pairs and template standards for MEST
- OriGene qPCR primer pairs for MEST
- OriGene CRISPR knockouts for MEST
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MEST
- GenScript: Next-day shipping of latest version cDNA ORF clones for MEST in any vector
- GenScript Custom Purified and Recombinant Proteins Services for MEST
- GenScript Custom Assay Services for MEST
- GenScript Custom overexpressing Cell Line Services for MEST
- GenScript: Design CRISPR guide RNA sequences for MEST
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for MEST
- Sino Biological Human cDNA Clone for MEST
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for MEST
- Novus Biologicals lysates and proteins for MEST
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for MEST
- Abcam proteins for MEST
- Find your target
- Browse Primary Antibodies
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- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
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- VectorBuilder custom plasmid, inducible vectors for MEST
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MEST
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 26 available MEST Antibodies ranked by validation data
- Compare Top MEST Antibodies
- antibodies-online: Search results for 5 available MEST Elisa Kits ranked by validation data
- Compare Top MEST Elisa Kits
- Quality Products:
- antibodies-online: Search results for 4 available MEST Proteins ranked by validation data
- Compare Top MEST Proteins
- Quality Products:
- GeneTex MEST Antibody for MEST
- Search GeneTex for Proteins for MEST
- Horizon Cell Lines for MEST
- genomics-online: cdna clones - Search results for 163 available MEST gene related products
- Overview of 163 available MEST gene related products
- orf clones - Search results for 163 available MEST gene related products
- Overview of 163 available MEST gene related products
- genomics-online: gRNA clones - Search results for 163 available MEST gene related products
- Overview of 163 available MEST gene related products
- genomics-online: primer clones - Search results for 163 available MEST gene related products
- Overview of 163 available MEST gene related products
- genomics-online: shRNA clones - Search results for 163 available MEST gene related products
- Overview of 163 available MEST gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MEST
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MEST
- GeneCopoeia miRNA 3'UTR Target clone products for MEST
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MEST
Sources for MEST Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt