Aliases for MEST Gene
External Ids for MEST Gene
Previous GeneCards Identifiers for MEST Gene
This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15. [provided by RefSeq, Dec 2011]
GeneCards Summary for MEST Gene
MEST (Mesoderm Specific Transcript) is a Protein Coding gene. Diseases associated with MEST include Uniparental Disomy Of Chromosome 7 and Kidney Cortex Disease. Gene Ontology (GO) annotations related to this gene include hydrolase activity. An important paralog of this gene is ABHD5.