Aliases for MEOX2 Gene
Aliases for MEOX2 Gene
External Ids for MEOX2 Gene
- HGNC: 7014
- Entrez Gene: 4223
- Ensembl: ENSG00000106511
- OMIM: 600535
- UniProtKB: P50222
Previous HGNC Symbols for MEOX2 Gene
- GAX
Previous GeneCards Identifiers for MEOX2 Gene
- GC07M015295
- GC07M015395
- GC07M015424
Summaries for MEOX2 Gene
-
This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease. [provided by RefSeq, Jul 2008]
GeneCards Summary for MEOX2 Gene
MEOX2 (Mesenchyme Homeobox 2) is a Protein Coding gene. Diseases associated with MEOX2 include Female Stress Incontinence and Low Compliance Bladder. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding. An important paralog of this gene is MEOX1.
UniProtKB/Swiss-Prot for MEOX2 Gene
-
Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (By similarity). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (PubMed:22206000). May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MEOX2 Gene
Genomics for MEOX2 Gene
GeneHancer (GH) Regulatory Elements for MEOX2 Gene
Promoters and enhancers for MEOX2 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH07J015680 | Promoter/Enhancer | 1.6 | EPDnew Ensembl ENCODE dbSUPER | 650.7 | +2.4 | 2362 | 8.7 | CTCF SUZ12 MAX SIN3A CEBPG YY1 POLR2A TCF7L2 EZH2 RXRA | MEOX2 LINC02587 LOC105375166 GC07P015321 | |
| GH07J015797 | Enhancer | 0.2 | ENCODE | 10.9 | -111.3 | -111289 | 1.3 | ENSG00000225974 LINC02587 MEOX2 GC07P015800 LOC105375167 LOC101927558 | ||
| GH07J015936 | Enhancer | 0.2 | ENCODE | 6.9 | -250.2 | -250221 | 1.5 | MEOX2 GC07M015939 ENSG00000229379 ISPD | ||
| GH07J015669 | Enhancer | 0.5 | ENCODE dbSUPER | 0.4 | +16.9 | 16888 | 1.7 | CEBPG | MEOX2 LOC105375166 GC07P015321 | |
| GH07J015667 | Enhancer | 0.4 | ENCODE dbSUPER | 0.4 | +18.8 | 18838 | 1.3 | MEOX2 LOC105375166 GC07P015321 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around MEOX2 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the MEOX2 gene promoter:
-
- TBP
- NF-kappaB1
- NF-kappaB
- IRF-1
- GATA-3
- GATA-2
Regulatory Element Products
Genomic Locations for MEOX2 Gene
Genomic Locations for MEOX2 Gene
- chr7:15,611,212-15,686,812
- (GRCh38/hg38)
- Size:
- 75,601 bases
- Orientation:
- Minus strand
- chr7:15,650,837-15,726,437
- (GRCh37/hg19)
- Size:
- 75,601 bases
- Orientation:
- Minus strand
Genomic View for MEOX2 Gene
Genes around MEOX2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 7p21.2 by Entrez Gene
- 7p21.2 by HGNC
- 7p21.2 by Ensembl
MEOX2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MEOX2 Gene
Proteins for MEOX2 Gene
-
Protein details for MEOX2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P50222-MEOX2_HUMAN
- Recommended name:
- Homeobox protein MOX-2
- Protein Accession:
- P50222
- A4D127
- B2R8I7
- O75263
- Q9UPL6
Protein attributes for MEOX2 Gene
- Size:
- 304 amino acids
- Molecular mass:
- 33594 Da
- Quaternary structure:
-
- Interacts with RNF10.
Protein Expression for MEOX2 Gene
Post-translational modifications for MEOX2 Gene
Other Protein References for MEOX2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
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-
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-
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-
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- antibodies-online: Search results for 8 available MEOX2 Proteins ranked by validation data
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-
Abcam proteins for MEOX2
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- antibodies-online: Search results for 1 available MEOX2 Elisa Kits ranked by validation data
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No data available for DME Specific Peptides for MEOX2 Gene
Domains & Families for MEOX2 Gene
Gene Families for MEOX2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for MEOX2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for MEOX2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P50222UniProtKB/Swiss-Prot:
MEOX2_HUMAN :- The polyhistidine repeat may act as a targeting signal to nuclear speckles.
- Domain:
-
- The polyhistidine repeat may act as a targeting signal to nuclear speckles.
Function for MEOX2 Gene
Molecular function for MEOX2 Gene
- UniProtKB/Swiss-Prot Function:
- Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (By similarity). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (PubMed:22206000). May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
- GENATLAS Biochemistry:
- mesenchyme homeo box, murine Mox2,homolog
Phenotypes From GWAS Catalog for MEOX2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IDA | 17074759 |
| GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | IDA | 17074759 |
| GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding | NAS | 19274049 |
| GO:0001077 | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | IMP | 17074759 |
| GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding | IMP | 17074759 |
Phenotypes for MEOX2 Gene
- MGI mutant phenotypes for MEOX2:
-
inferred from 4 alleles
- cardiovascular system phenotype
- respiratory system phenotype
- limbs/digits/tail phenotype
- digestive/alimentary phenotype
- homeostasis/metabolism phenotype
- nervous system phenotype
- behavior/neurological phenotype
- no phenotypic analysis
- neoplasm
- integument phenotype
- taste/olfaction phenotype
- endocrine/exocrine gland phenotype
- mortality/aging
- cellular phenotype
- muscle phenotype
- craniofacial phenotype
- liver/biliary system phenotype
- reproductive system phenotype
- skeleton phenotype
- embryo phenotype
- normal phenotype
- renal/urinary system phenotype
- adipose tissue phenotype
- hematopoietic system phenotype
- immune system phenotype
- growth/size/body region phenotype
- GenomeRNAi human phenotypes for MEOX2:
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-
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miRNA for MEOX2 Gene
- miRTarBase miRNAs that target MEOX2
-
- hsa-mir-301a-3p (MIRT003611)
- hsa-mir-130a-3p (MIRT004358)
- hsa-mir-335-5p (MIRT018453)
- hsa-mir-221-3p (MIRT024208)
- hsa-mir-320a (MIRT044481)
- hsa-mir-6809-3p (MIRT714955)
- hsa-mir-6833-3p (MIRT714956)
- hsa-mir-4768-5p (MIRT714957)
- hsa-mir-4684-5p (MIRT714958)
- hsa-mir-4742-3p (MIRT714959)
- hsa-mir-138-1-3p (MIRT714960)
- hsa-mir-1183 (MIRT714961)
miRNA Products
Inhibitory RNA Products
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- Applied Biological Materials Clones for MEOX2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for MEOX2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MEOX2 Gene
Localization for MEOX2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for MEOX2 Gene
- Nucleus. Nucleus speckle.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA,IDA | 22206000 |
| GO:0005737 | cytoplasm | IDA | 16335786 |
| GO:0016607 | nuclear speck | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for MEOX2 Gene
Pathways & Interactions for MEOX2 Gene
No Data Available
Interacting Proteins for MEOX2 Gene
Selected Interacting proteins:
P50222-MEOX2_HUMAN
ENSP00000262041
for MEOX2 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for MEOX2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001525 | angiogenesis | IEA | -- |
| GO:0001757 | somite specification | IEA | -- |
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006366 | transcription by RNA polymerase II | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for MEOX2 Gene
Transcripts for MEOX2 Gene
mRNA/cDNA for MEOX2 Gene
- (1) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (72) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000262041 2500 bps (uc003stc.4)
Unigene Clusters for MEOX2 Gene
- Mesenchyme homeobox 2:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for MEOX2
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-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MEOX2
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miRNA Products
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Clone Products
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-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for MEOX2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Adipose (Muscoskeletal System)
- Lumbar Brown Adipocyte Cells Lumbar Brown Adipose Depot
- Thoracic Committed Brown Preadipocytes Thoracic Brown Adipose Depot
- Lumbar Committed Brown Preadipocytes Lumbar Brown Adipose Depot
- Cervical Brown Adipocyte Cells Cervical Brown Adipose Depot
- Thoracic Brown Adipocyte Cells Thoracic Brown Adipose Depot
-
Kidney (Urinary System)
- Metanephric Mesenchyme Cells Metanephric Mesenchyme
- Renal Vesicle
-
Limb (Muscoskeletal System)
- Limb Muscle Progenitor Cells Hindlimb Myotome
- Limb Muscle Progenitor Cells Forelimb Myotome
-
Skeletal Muscle (Muscoskeletal System)
- Limb Muscle Progenitor Cells Hindlimb Myotome
- Limb Muscle Progenitor Cells Forelimb Myotome
- Bone (Muscoskeletal System)
-
Lung (Respiratory System)
-
Dermis (Integumentary System)
-
Heart (Cardiovascular System)
mRNA differential expression in normal tissues according to GTEx for MEOX2 Gene
This gene is overexpressed in Nerve - Tibial (x8.9), Adipose - Subcutaneous (x5.9), Artery - Tibial (x5.2), and Adipose - Visceral (Omentum) (x4.2).
This gene is overexpressed in Fetal heart (61.6) and Placenta (7.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for MEOX2 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of MEOX2 Gene:
MEOX2SOURCE GeneReport for Unigene cluster for MEOX2 Gene:
Hs.170355mRNA Expression by UniProt/SwissProt for MEOX2 Gene:
P50222-MEOX2_HUMAN
Tissue specificity:
Embryo and placenta.
Evidence on tissue expression from TISSUES for MEOX2 Gene
- Heart(4.4)
- Skin(4.2)
- Muscle(2.4)
Primer Products
-
OriGene qPCR primer pairs for MEOX2
-
OriGene qPCR primer pairs and template standards for MEOX2
- genomics-online: primer clones - Search results for available MEOX2 gene related products
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for MEOX2 Gene
Orthologs for MEOX2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | MEOX2 34 33 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | MEOX2 34 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | MEOX2 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | MEOX2 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Meox2 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Meox2 16 34 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | MEOX2 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | MEOX2 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | MEOX2 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | meox2 33 |
|
||
| Str.10254 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | meox2-prov 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | MEOX2 (1 of 2) 34 |
|
OneToMany | |
| meox2b 34 |
|
OneToMany | |||
| LOC556898 33 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | btn 34 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for MEOX2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for MEOX2 Gene
- ENSEMBL:
- Gene Tree for MEOX2 (if available)
- TreeFam:
- Gene Tree for MEOX2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MEOX2: view image
Paralogs for MEOX2 Gene
Variants for MEOX2 Gene
Polymorphic Variants from UniProtKB/Swiss-Prot for MEOX2 Gene
- MEOX2_HUMAN-P50222
- The poly-His region of MEOX2 is polymorphic and the number of His varies in the population.
| SNP ID | Clin | Chr 07 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000010593 | -- | 15,630,812(-) | T/C | intron_variant | |
| rs1000029939 | -- | 15,625,542(-) | A/G | intron_variant | |
| rs1000070240 | -- | 15,672,878(-) | C/A/T | intron_variant | |
| rs1000134234 | -- | 15,616,352(-) | A/G | intron_variant | |
| rs1000187451 | -- | 15,684,804(-) | C/T | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv27709 | CNV | loss | 19812545 |
| esv3309437 | CNV | mobile element insertion | 20981092 |
| nsv1018250 | CNV | loss | 25217958 |
| nsv1161502 | CNV | duplication | 26073780 |
| nsv464392 | CNV | loss | 19166990 |
| nsv523199 | CNV | gain | 19592680 |
| nsv606283 | CNV | gain | 21841781 |
| nsv606310 | CNV | loss | 21841781 |
| nsv824016 | CNV | loss | 20364138 |
| nsv830911 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
70.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.44;
71.45% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MEOX2 Gene
SNP Genotyping and Copy Number Assay Products
Disorders for MEOX2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| female stress incontinence |
|
|
| low compliance bladder |
|
|
| vesicoureteral reflux 1 |
|
|
| alzheimer disease |
|
|
| cleft palate, isolated |
|
|
Search MEOX2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for MEOX2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for MEOX2 Gene
Publications for MEOX2 Gene
- Characterization of Mesenchyme Homeobox 2 (MEOX2) transcription factor binding to RING finger protein 10. (PMID: 16335786) Lin J … Wigle JT (Molecular and cellular biochemistry 2005) 3 4 22 58
- Isolation of the human MOX2 homeobox gene and localization to chromosome 7p22.1-p21.3. (PMID: 7607679) Grigoriou M … Karagogeos D (Genomics 1995) 3 4 22 58
- Molecular cloning and localization of the human GAX gene to 7p21. (PMID: 7713505) LePage DF … Walsh K (Genomics 1994) 2 3 4 58
- Mechanisms of MEOX1 and MEOX2 regulation of the cyclin dependent kinase inhibitors p21 and p16 in vascular endothelial cells. (PMID: 22206000) Douville JM … Wigle JT (PloS one 2011) 3 4 58
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
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- Santa Cruz Biotechnology (SCBT) Antibodies for MEOX2
- Search Santa Cruz Biotechnology (SCBT) for MEOX2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for MEOX2
- Horizon Cell Lines for MEOX2
- genomics-online: cdna clones - Search results for available MEOX2 gene related products
- orf clones - Search results for available MEOX2 gene related products
- genomics-online: gRNA clones - Search results for available MEOX2 gene related products
- genomics-online: primer clones - Search results for available MEOX2 gene related products
- genomics-online: shRNA clones - Search results for available MEOX2 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MEOX2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MEOX2
- GeneCopoeia miRNA 3'UTR Target clone products for MEOX2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MEOX2
- Boster Bio Antibodies for MEOX2
- Browse Boster Bio ELISA Kits
Sources for MEOX2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt