Aliases for MEIS3 Gene
External Ids for MEIS3 Gene
Previous GeneCards Identifiers for MEIS3 Gene
This gene encodes a homeobox protein and probable transcriptional regulator. The orthologous protein in mouse controls expression of 3-phosphoinositide dependent protein kinase 1, which promotes survival of pancreatic beta-cells. [provided by RefSeq, Sep 2016]
GeneCards Summary for MEIS3 Gene
MEIS3 (Meis Homeobox 3) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific. An important paralog of this gene is MEIS2.
UniProtKB/Swiss-Prot Summary for MEIS3 Gene
Transcriptional regulator which directly modulates PDPK1 expression, thus promoting survival of pancreatic beta-cells. Also regulates expression of NDFIP1, BNIP3, and CCNG1.