Aliases for MED29 Gene
External Ids for MED29 Gene
Previous HGNC Symbols for MED29 Gene
Previous GeneCards Identifiers for MED29 Gene
MED29 is a subunit of the Mediator complex, a multiprotein coactivator of RNA transcription that interacts with DNA-bound transcriptional activators, RNA polymerase II (see MIM 180660), and general initiation factors (Sato et al., 2003 [PubMed 14576168]).[supplied by OMIM, Aug 2009]
GeneCards Summary for MED29 Gene
MED29 (Mediator Complex Subunit 29) is a Protein Coding gene. Diseases associated with MED29 include Horner's Syndrome and Enophthalmos. Among its related pathways are Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) and Metabolism.
UniProtKB/Swiss-Prot Summary for MED29 Gene
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.