Aliases for MED26 Gene
Aliases for MED26 Gene
External Ids for MED26 Gene
- HGNC: 2376
- Entrez Gene: 9441
- Ensembl: ENSG00000105085
- OMIM: 605043
- UniProtKB: O95402
Previous HGNC Symbols for MED26 Gene
- CRSP7
Previous GeneCards Identifiers for MED26 Gene
- GC19M016546
- GC19M016685
- GC19M016254
Summaries for MED26 Gene
-
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq, Jul 2008]
GeneCards Summary for MED26 Gene
MED26 (Mediator Complex Subunit 26) is a Protein Coding gene. Among its related pathways are Gene Expression and Metabolism. Gene Ontology (GO) annotations related to this gene include transcription coactivator activity. An important paralog of this gene is ENSG00000141979.
UniProtKB/Swiss-Prot for MED26 Gene
-
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MED26 Gene
Genomics for MED26 Gene
GeneHancer (GH) Regulatory Elements for MED26 Gene
Promoters and enhancers for MED26 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around MED26 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the MED26 gene promoter:
-
- RORalpha1
- GR-alpha
- GR
- Max1
- c-Myc
- Meis-1
- Meis-1a
- Meis-1b
- GATA-6
- Msx-1
Regulatory Element Products
Genomic Locations for MED26 Gene
Genomic Locations for MED26 Gene
- chr19:16,574,907-16,629,062
- (GRCh38/hg38)
- Size:
- 54,156 bases
- Orientation:
- Minus strand
- chr19:16,685,718-16,739,873
- (GRCh37/hg19)
- Size:
- 54,156 bases
- Orientation:
- Minus strand
Genomic View for MED26 Gene
Genes around MED26 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19p13.11 by Entrez Gene
- 19p13.11 by HGNC
- 19p13.11 by Ensembl
MED26 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MED26 Gene
Proteins for MED26 Gene
-
Protein details for MED26 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O95402-MED26_HUMAN
- Recommended name:
- Mediator of RNA polymerase II transcription subunit 26
- Protein Accession:
- O95402
- A1A4S3
- Q0VGB6
Protein attributes for MED26 Gene
- Size:
- 600 amino acids
- Molecular mass:
- 65446 Da
- Quaternary structure:
-
- Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP. Interacts with CEBPB (when not methylated)(PubMed:20111005).
Protein Expression for MED26 Gene
Post-translational modifications for MED26 Gene
Other Protein References for MED26 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for MED26
-
Abcam antibodies for MED26
- Invitrogen Antibodies for MED26
- GeneTex MED26 Antibody for MED26
-
Santa Cruz Biotechnology (SCBT) Antibodies for MED26
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MED26
- Origene Custom Protein Services for MED26
- Search GeneTex for Proteins for MED26
-
Abcam proteins for MED26
Assay Products
No data available for DME Specific Peptides for MED26 Gene
Domains & Families for MED26 Gene
Gene Families for MED26 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for MED26 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for MED26 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O95402- Family:
-
- Belongs to the Mediator complex subunit 26 family.
Function for MED26 Gene
Molecular function for MED26 Gene
- UniProtKB/Swiss-Prot Function:
- Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.
Phenotypes From GWAS Catalog for MED26 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003713 | transcription coactivator activity | TAS | 9989412 |
| GO:0005515 | protein binding | IPI | 15175163 |
Phenotypes for MED26 Gene
- GenomeRNAi human phenotypes for MED26:
-
- Decreased shRNA abundance (Z-score < -2)
- Decreased DCP1a protein expression and assembly in processing bodies after arsenite stimulation
- Decreased HIV-LTR-beta-galactosidase protein expression
- Decreased Tat-dependent HIV-LTR-beta-galactosidase protein expression
- Decreased ionizing radiation sensitivity
- Increased shRNA abundance (Z-score > 2)
- Increased Nanog expression
- Decreased viability
- no effect
- Increased caspase activity
- Decreased Aire reporter expression
- Increased vaccinia virus (VACV) infection
- Increased gamma-H2AX phosphorylation
- Decreased NF-kappaB reporter expression
- shRNA abundance <= 50%
- Increased viability
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MED26
-
CRISPR Products
-
OriGene CRISPR knockouts for MED26
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- genomics-online: gRNA clones - Search results for 79 available MED26 gene related products
- Overview of 79 available MED26 gene related products
- Applied Biological Materials CRISPR for MED26
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MED26
- GenScript: Design CRISPR guide RNA sequences for MED26
miRNA for MED26 Gene
- miRTarBase miRNAs that target MED26
-
- hsa-mir-320a (MIRT044629)
- hsa-mir-8055 (MIRT564288)
- hsa-mir-1304-5p (MIRT564289)
- hsa-mir-6734-5p (MIRT564290)
- hsa-mir-1226-5p (MIRT564291)
- hsa-mir-6834-5p (MIRT564292)
- hsa-mir-513b-5p (MIRT564293)
- hsa-mir-6077 (MIRT564294)
- hsa-mir-2052 (MIRT564295)
- hsa-mir-6133 (MIRT564296)
- hsa-mir-6130 (MIRT564297)
- hsa-mir-6129 (MIRT564298)
- hsa-mir-6127 (MIRT564299)
- hsa-mir-4510 (MIRT564300)
- hsa-mir-4419a (MIRT564301)
- hsa-mir-6875-5p (MIRT564302)
- hsa-mir-3126-5p (MIRT564303)
- hsa-mir-4719 (MIRT564304)
- hsa-mir-9500 (MIRT564305)
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for MED26
- Browse OriGene Inhibitory RNA Products For MED26
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MED26
- genomics-online: shRNA clones - Search results for 79 available MED26 gene related products
- Overview of 79 available MED26 gene related products
Clone Products
- Sino Biological Human cDNA Clone for MED26
- VectorBuilder custom plasmid, inducible vectors for MED26
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MED26
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for MED26
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MED26
- Applied Biological Materials Clones for MED26
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MED26 Gene
Localization for MED26 Gene
Subcellular locations from UniProtKB/Swiss-Prot for MED26 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
- Cytosol (2)
- Nucleoplasm (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0016592 | mediator complex | IDA | 15989967 |
Pathways & Interactions for MED26 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | ||
| 2 | Gene Expression |
.48
|
|
| 3 | Metabolism |
.37
|
|
| 4 | Chromatin Regulation / Acetylation | ||
| 5 | Developmental Biology | ||
Pathways by source for MED26 Gene
9 Reactome pathways for MED26 Gene
1 Cell Signaling Technology pathway for MED26 Gene
Interacting Proteins for MED26 Gene
Selected Interacting proteins:
O95402-MED26_HUMAN
ENSP00000263390
for MED26 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for MED26
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006357 | regulation of transcription by RNA polymerase II | IDA,TAS | 15989967 |
| GO:0006367 | transcription initiation from RNA polymerase II promoter | TAS | -- |
No data available for SIGNOR curated interactions for MED26 Gene
Transcripts for MED26 Gene
mRNA/cDNA for MED26 Gene
- (1) REFSEQ mRNAs :
- (14) Additional mRNA sequences :
- (76) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000597244 3871 bps (uc060vae.1)
- ENST00000263390 3174 bps (uc002nen.2)
- ENST00000611692 1444 bps (uc060vaf.1)
- ENST00000598492 539 bps (uc060vag.1)
- ENST00000598608 742 bps (uc060vah.1)
Unigene Clusters for MED26 Gene
- Mediator complex subunit 26:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for MED26
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MED26
- genomics-online: gRNA clones - Search results for 79 available MED26 gene related products
- Overview of 79 available MED26 gene related products
- Applied Biological Materials CRISPR for MED26
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MED26
- GenScript: Design CRISPR guide RNA sequences for MED26
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for MED26
- Browse OriGene Inhibitory RNA Products For MED26
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MED26
- genomics-online: shRNA clones - Search results for 79 available MED26 gene related products
- Overview of 79 available MED26 gene related products
Clone Products
- Sino Biological Human cDNA Clone for MED26
- VectorBuilder custom plasmid, inducible vectors for MED26
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MED26
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for MED26
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MED26
- Applied Biological Materials Clones for MED26
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for MED26 Gene
mRNA differential expression in normal tissues according to GTEx for MED26 Gene
This gene is overexpressed in Testis (x12.1).
This gene is overexpressed in Heart (42.1) and Pancreatic juice (19.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MED26 Gene
NURSA nuclear receptor signaling pathways regulating expression of MED26 Gene:
MED26SOURCE GeneReport for Unigene cluster for MED26 Gene:
Hs.715040Primer Products
-
OriGene qPCR primer pairs and template standards for MED26
-
OriGene qPCR primer pairs for MED26
- genomics-online: primer clones - Search results for 79 available MED26 gene related products
- Overview of 79 available MED26 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MED26 Gene
Orthologs for MED26 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | -- 34 |
|
OneToMany | |
| MED26 33 |
|
||||
| dog (Canis familiaris) |
Mammalia | -- 34 |
|
OneToMany | |
| MED26 33 |
|
||||
| cow (Bos Taurus) |
Mammalia | MED26 34 33 |
|
OneToMany | |
| rat (Rattus norvegicus) |
Mammalia | Med26 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Med26 16 34 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
| oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
OneToMany | |
| chicken (Gallus gallus) |
Aves | MED26 33 |
|
||
| -- 34 |
|
OneToMany | |||
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | med26 33 |
|
||
| Str.1314 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.12095 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | crsp7 33 |
|
||
| MED26 34 |
|
OneToMany | |||
| Dr.11494 33 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | MED26 34 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for MED26 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for MED26 Gene
- ENSEMBL:
- Gene Tree for MED26 (if available)
- TreeFam:
- Gene Tree for MED26 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MED26: view image
Paralogs for MED26 Gene
Paralogs for MED26 Gene
(2) SIMAP similar genes for MED26 Gene using alignment to 5 proteins:
- MED26_HUMAN
- M0QXW8_HUMAN
- M0R064_HUMAN
- M0R2P1_HUMAN
- M0R2Y4_HUMAN
Variants for MED26 Gene
| SNP ID | Clin | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000055623 | -- | 16,583,098(-) | T/C | intron_variant | |
| rs1000134506 | -- | 16,624,194(-) | C/A | intron_variant | |
| rs1000141752 | -- | 16,609,293(-) | C/G | intron_variant | |
| rs1000196851 | -- | 16,611,566(-) | T/C | intron_variant | |
| rs1000241311 | -- | 16,618,170(-) | C/T | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2674048 | CNV | deletion | 23128226 |
| esv2718266 | CNV | deletion | 23290073 |
| nsv479037 | CNV | novel sequence insertion | 20440878 |
| nsv510757 | CNV | deletion | 20534489 |
Residual Variation Intolerance Score:
11.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.54;
29.78% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MED26 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MED26 Gene
Disorders for MED26 Gene
Additional Disease Information for MED26
No disorders were found for MED26 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MED26 Gene
Publications for MED26 Gene
- The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1. (PMID: 9989412) Ryu S … Tjian R (Nature 1999) 2 3 4 58
- Crosstalk between C/EBPbeta phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code. (PMID: 20111005) Kowenz-Leutz E … Leutz A (The EMBO journal 2010) 3 4 58
- MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription. (PMID: 15989967) Zhang X … Roeder RG (Molecular cell 2005) 3 4 58
- A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. (PMID: 15175163) Sato S … Conaway RC (Molecular cell 2004) 3 4 58
- Composite co-activator ARC mediates chromatin-directed transcriptional activation. (PMID: 10235267) Näär AM … Tjian R (Nature 1999) 3 4 58
Products for MED26 Gene
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- VectorBuilder custom plasmid, inducible vectors for MED26
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for MED26
- antibodies-online: Search results for 61 available MED26 Antibodies ranked by validation data
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- antibodies-online: Search results for 12 available MED26 Elisa Kits ranked by validation data
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- antibodies-online: Search results for 4 available MED26 Proteins ranked by validation data
- Compare Top MED26 Proteins
- GeneTex MED26 Antibody for MED26
- Search GeneTex for Proteins for MED26
- Santa Cruz Biotechnology (SCBT) Antibodies for MED26
- Search Santa Cruz Biotechnology (SCBT) for MED26 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for MED26
- genomics-online: cdna clones - Search results for 79 available MED26 gene related products
- Overview of 79 available MED26 gene related products
- orf clones - Search results for 79 available MED26 gene related products
- Overview of 79 available MED26 gene related products
- genomics-online: gRNA clones - Search results for 79 available MED26 gene related products
- Overview of 79 available MED26 gene related products
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- Overview of 79 available MED26 gene related products
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Sources for MED26 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
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- (74) GeneGo (Thomson Reuters)
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